CHANGES stands for CHinese-AmericaN-German E-Science and cyberinfrastructure. Partners are CNIC-CAS from China, NCSA-UIUC from USA and Jülich Supercomputing Centre at Forschungszentrum Jülich from Germany. The first CHANGES workshop is a high-level platform to discuss latest trends in supercomputing, sophisticated information techniques and interdisciplinary applications.