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Microelectrode Arrays

Microelectrodes are multi-purpose electrochemical / electronic devices that can be operated under diverse environmental conditions for an enormous variety of applications. We use utilizing mainly two types of chip based 2D multi-electrode systems for the detection of analyte molecules namely planar multi-electrode arrays (MEAs) and Interdigitated array (IDA) electrode. Both types of electrode chips are fabricated by standard Si cleanroom microfabrication technology at the Helmholtz Nanoelectronic facility (HNF) of the Forschungszentrum Juelich GmbH.


Multi-electrode arrays (MEA)

Our MEAs possess typically 64 noble metal electrodes on an area of 1cm². Each microelectrode can be independently electrically addressed and used to record simultaneously up to 64 channels. The electrodes are arranged in an array pattern of 8×8 electrodes. The chip is passivated by a dielectric layer against the analyte solution. The active areas of the microelectrodes are defined by small hole-like openings in the dielectric layer with a diameter ranging from 3 µm to 24 μm. MEAs own many advantages over macroelectrodes, such as high mass-transfer rate, small RC constants and faster electrochemical responses. We aim to modify the electrode surface by receptor molecules such as aptamers to facilitate multi-targets detection of related biomarkers or neurotransmitters.


Interdigitated array electrodes

Interdigitated array (IDA) electrodes are composed of a pair of microfabricated nobel metal or carbon electrodes. One electrode of these electrodes is used as generator electrode and the second as collector electrodes. The potentials of both electrodes can be controlled separately to allow signal amplification by redox cycling. One or both electrodes can be modified with receptor molecules to facilitate the detection of biochemical targets. Furthermore, we applied the concept of electrochemical rectification on IDA electrodes mimicking molecular logic gate operations as well as to realize transistor functions with signal amplification. We intend to implement these concepts into electrochemical sensor systems. Our goal is to combine logic and sensing operations on microelectrodes to advance the performance of electrochemical biosensors.

Additional Information


Dr. Dirk Mayer

Tel.:  +49-2461-61-4023

More Information:


Transistor Functions Based on Electrochemical Rectification, Y. Liu et al, Angew. Chem. Int. Ed., 52, (2013) 4029


Electrochemical current rectification at bio-functionalized electrodes, Y. Liu et al, Bioelectrochemistry, 77, (2010) 89


An Electrochemically Transduced XOR Logic Gate at the Molecular Level, Y. Liu et al, Angew. Chem. Int. Ed., 49, (2010) 2595