Publikationen Prof. Dr. Bernd Neumaier
Journal Article
“Fill States”: PET-derived Markers of the Spatial Extent of Alzheimer Disease Pathology
Radiology 314(3), e241482 (2025) [10.1148/radiol.241482]
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Journal Article
Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity
Nature metabolism 7, 297–320 (2025) [10.1038/s42255-024-01196-4]
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Journal Article
Do you know your PSMA-tracer? Variability in the biodistribution of different PSMA ligands and its potential impact on defining PSMA-positivity prior to PSMA-targeted therapy
EJNMMI Research 15(1), 4 (2025) [10.1186/s13550-024-01190-7]
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Journal Article - Online First
Autoradiography of Intracerebral Tumours in the Chick Embryo Model: A Feasibility Study Using Different PET Tracers
Molecular imaging & biology 27(1), - (2025) [10.1007/s11307-025-01983-9]
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Journal Article
[18F]R91150: Improved radiosynthesis and in vivo evaluation as imaging probe for 5-HT2A receptors
European journal of medicinal chemistry 286, 117265 (2025) [10.1016/j.ejmech.2025.117265]
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Journal Article
Effect of Acute Hypoxia Exposure on the Availability of A1 Adenosine Receptors and Perfusion in the Human Brain
Journal of nuclear medicine 66(1), 142 - 149 (2025) [10.2967/jnumed.124.268455]
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Journal Article
Fully automated production of (((S)-1-carboxy-5-(6-([18F]fluoro)-2-methoxynicotinamido)pentyl)carbamoyl)-l-glutamic acid ([18F]JKPSMA-7
Pharmaceuticals 18(1), 119 - (2025) [10.3390/ph18010119]
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Journal Article
Cross sections for the formation of 84m,gRb, 83Rb, and 82mRb in 86Sr(d,x) reactions up to deuteron energies of 49 MeV: Competition between α -particle and multinucleon emission processes
Physical review / C 110(6), 064608 (2024) [10.1103/PhysRevC.110.064608]
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Journal Article
Preserved striatal innervation maintains motor function despite severe loss of nigral dopaminergic neurons
Brain 147(9), 3189 - 3203 (2024) [10.1093/brain/awae089]
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Journal Article
Cerebellar Metabolic Connectivity during Treadmill Walking before and after Unilateral Dopamine Depletion in Rats
International journal of molecular sciences 25(16), 8617 (2024) [10.3390/ijms25168617]
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Journal Article
Improved Tau PET SUVR Quantification in 4-Repeat Tau Phenotypes with [18F]PI-2620
Journal of nuclear medicine 65(6), 952 - 955 (2024) [10.2967/jnumed.123.265930]
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Journal Article
Repeated caffeine intake suppresses cerebral grey matter responses to chronic sleep restriction in an A1 adenosine receptor-dependent manner: a double-blind randomized controlled study with PET-MRI
Scientific reports 14(1), 12724 (2024) [10.1038/s41598-024-61421-8]
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Journal Article
Excitation functions of 72Ge(p,xn)72,71As reactions from threshold up to 45 MeV for production of the non-standard positron emitter 72As
Scientific reports 14(1), 16724 (2024) [10.1038/s41598-024-67319-9]
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Journal Article
Preparation and Preclinical Evaluation of 18F-Labeled Olutasidenib Derivatives for Non-Invasive Detection of Mutated Isocitrate Dehydrogenase 1 (mIDH1)
Molecules 29(16), 3939 (2024) [10.3390/molecules29163939]
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Journal Article
Progressive Supranuclear Palsy: Subcortical Tau Depositions Are Associated with Cortical Perfusion in Frontal and Limbic Regions
Journal of Parkinson's Disease 14(6), 1271-1276 (2024) [10.3233/JPD-240210]
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Journal Article
Excitation functions and isomeric cross-section ratios of (d,xn) reactions on 86Sr
The European physical journal / A 60(6), 128 (2024) [10.1140/epja/s10050-024-01330-6]
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Conference Presentation (After Call)
Synthese und Stabilitätsuntersuchung eines potenziellen kovalenten FAP-Inhibitors
62. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, DGN 2024, LeipzigLeipzig, Germany, 10 Apr 2024 - 13 Apr 2024
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Conference Presentation (After Call)
Development and preclinical evaluation of radiofluorinated olutasidenib derivatives for non-invasive detection of mutated isocitrate dehydrogenase 1 (mIDH1) in gliomas
62. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, DGN 2024, LeipzigLeipzig, Germany, 10 Apr 2024 - 13 Apr 2024
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Conference Presentation (After Call)
Indirekte Radiofluorierung von nativem Insulin mit 1-Methylamino-7-[F-18]fluor-8-azaisatosäureanhydrid ([F-18]MFA)
62. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, DGN 2024, LeipzigLeipzig, Germany, 10 Apr 2024 - 13 Apr 2024
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Conference Presentation (After Call)
Radiosynthese und präklinische Evaluation von meta-[F-18]FET und [F-18]FET-OMe
62. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, DGN 2024, LeipzigLeipzig, Germany, 10 Apr 2024 - 13 Apr 2024
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Conference Presentation (After Call)
F-18-R91150: Optimierte Radiosynthese und In-vivo Evaluation als 5-HT2A-spezifischer Radioligand
62. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, DGN 2024, LeipzigLeipzig, Germany, 10 Apr 2024 - 13 Apr 2024
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Journal Article
Radiosynthesis and Preclinical Evaluation of m-[18F]FET and [18F]FET-OMe as Novel [18F]FET Analogs for Brain Tumor Imaging
Molecular pharmaceutics 21, 2795-2812 (2024) [10.1021/acs.molpharmaceut.3c01215]
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Journal Article
Radiosynthesis and In Vitro Evaluation of [11C]tozadenant as Adenosine A2A Receptor Radioligand
Molecules 29(5), 1089 (2024) [10.3390/molecules29051089]
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Journal Article
Glutamate Signaling in Patients With Parkinson Disease With REM Sleep Behavior Disorder
Neurology 102(9), e209271 (2024) [10.1212/WNL.0000000000209271]
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Journal Article
8-Bicycloalkyl-CPFPX derivatives as potent and selective tools for in vivo imaging of the A1 adenosine receptor
European journal of medicinal chemistry 271, 116380 (2024) [10.1016/j.ejmech.2024.116380]
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Journal Article
Desmethyl SuFEx-IT: SO2F2 - Free Synthesis and Evaluation as a Fluorosulfurylating Agent
The journal of organic chemistry 89(6), 3821-3833 (2024) [10.1021/acs.joc.3c02643]
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Journal Article
Fragmentation of functional resting state brain networks in a transgenic mouse model of tau pathology: A metabolic connectivity study using [18F]FDG-PET
Experimental neurology 372, 114632 - (2024) [10.1016/j.expneurol.2023.114632]
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Journal Article
Radiochemical isolation of 45Ti using ion chromatography
Journal of radioanalytical and nuclear chemistry 333, 3631–3637 (2024) [10.1007/s10967-023-09270-z]
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Journal Article
Assessment of Brain Tumour Perfusion Using Early-Phase 18F-FET PET: Comparison with Perfusion-Weighted MRI
Molecular imaging & biology 26, 36-44 (2024) [10.1007/s11307-023-01861-2]
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Conference Presentation (After Call)
Quantitative Rezeptor-PET in der präklinischen Bildgebung: Vergleich von intravenöser und intraperitonealer Radiotracerapplikation anhand des Beispiels des Adenosin A1 Rezeptor-Tracers F-18-CPFPX
61. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, LeipzigLeipzig, Germany, 19 Apr 2023 - 22 Apr 2023
[10.1055/s-0043-1766348]
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Conference Presentation (After Call)
SV2A-PET in a tauopathy mouse model
61. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, LeipzigLeipzig, Germany, 19 Apr 2023 - 22 Apr 2023
[10.1055/s-0043-1766342]
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Conference Presentation (After Call)
Nachsäuleninjektion als Verfahren zur schnellen und präzisen Quantifizierung von Radioprodukten mittels analytischer HPLC
61. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, LeipzigLeipzig, Germany, 19 Apr 2023 - 22 Apr 2023
[10.1055/s-0043-1766334]
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Conference Presentation (After Call)
SuFEx 18F-Fluorierung von Sulfamoylfluoriden und deren in vivo Stabilität
61. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, LeipzigLeipzig, Germany, 19 Apr 2023 - 22 Apr 2023
[10.1055/s-0043-1766332]
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Conference Presentation (After Call)
Regional grey-matter A1 adenosine receptor expression in patients with early-stage Multiple Sclerosis: An in vivo PET study
61. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, LeipzigLeipzig, Germany, 19 Apr 2023 - 22 Apr 2023
[10.1055/s-0043-1766271]
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Conference Presentation (After Call)
Beziehung der Verfügbarkeit von A1-Adenosinrezeptoren im menschlichen Gehirn zur Alpha-Leistungsdichte in der Wach-Elektroenzephalographie
61. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, LeipzigLeipzig, Germany, 19 Apr 2023 - 22 Apr 2023
[10.1055/s-0043-1766270]
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Conference Presentation (After Call)
Neue Cu-Komplexe für die effiziente Herstellung von F-18-markierten Aromaten
61. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, LeipzigLeipzig, Germany, 19 Apr 2023 - 22 Apr 2023
[10.1055/s-0043-1766258]
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Conference Presentation (After Call)
Effect of acute hypoxia exposure on the availability of A1 adenosine receptors in the human brain measured with [F-18]CPFPX PET
61. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, LeipzigLeipzig, Germany, 19 Apr 2023 - 22 Apr 2023
[10.1055/s-0043-1766157]
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Conference Presentation (After Call)
Determination of positron emission intensity in the decay of 86gY
15th International Conference on Nuclear Data for Science and Technology, ND2022, ELECTR NETWORKELECTR NETWORK, Virtual Meeting, 21 Jul 2022 - 22 Jul 2022
(2023) [10.1051/epjconf/202328409003]
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Conference Presentation (After Call)
18F-Labelled inhibitors for targeting of IDH1 mutant gliomas
25th International Symposium on Radiopharmaceutical Sciences, ISRS2023, Honolulu, USAHonolulu, USA, USA, 22 May 2023 - 26 May 2023
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Conference Presentation (After Call)
Towards covalent fibroplast activation protein (FAP) inhibitors for delivery of therapeutic radionuclides into FAP-positive tumors
25th International Symposium on Radiopharmaceutical Sciences, ISRS2023, HonoluluHonolulu, USA, 22 May 2023 - 26 May 2023
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Conference Presentation (After Call)
4-Iodophenyl-[18F]fluorosulfate as a versatile building block for Pd-catalyzed cross-coupling reactions
25th International Symposium on Radiopharmaceutical Sciences, ISRS2023, HonoluluHonolulu, USA, 22 May 2023 - 26 May 2023
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Conference Presentation (After Call)
Evaluation of tetramethylammonium salts in minimalist-like SNAr radiofluorinations
25th International Symposium on Radiopharmaceutical Sciences, ISRS2023, HonoluluHonolulu, USA, 22 May 2023 - 26 May 2023
[10.34734/FZJ-2024-03440]
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Conference Presentation (After Call)
2,6-Bis-(N-hydroxylamino)-1,3,5-triazines as ligands for 45Ti-chelation
25th International Symposium on Radiopharmaceutical Sciences, ISRS2023, Honolulu, USAHonolulu, USA, USA, 22 May 2023 - 26 May 2023
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Conference Presentation (After Call)
Preparation and preclinical evaluation of novel 18F-labeled FAP ligands
25th International Symposium on Radiopharmaceutical Sciences, ISRS2023, Honolulu, USAHonolulu, USA, USA, 22 May 2023 - 26 May 2023
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Conference Presentation (After Call)
Next generation copper complexes for efficient production of radiolabeled aromatics
25th International Symposium on Radiopharmaceutical Sciences, ISRS2023, Honolulu, USAHonolulu, USA, USA, 22 May 2023 - 26 May 2023
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Conference Presentation (After Call)
Preparation of radiolabeled sulfamoyl fluorides by SuFEx 18F/19F isotopic exchange and assessment of their in vivo stability
25th International Symposium on Radiopharmaceutical Sciences, ISRS2023, Honolulu, USAHonolulu, USA, USA, 22 May 2023 - 26 May 2023
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Journal Article
TgF344-AD Rat Model of Alzheimer’s Disease: Spatial Disorientation and Asymmetry in Hemispheric Neurodegeneration
Journal of Alzheimer's disease reports 7(1), 1085 - 1094 (2023) [10.3233/ADR-230038]
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Journal Article
In Vivo Measurement of Tau Depositions in Anti-IgLON5 Disease Using [18F]PI-2620 PET
Neurology 101(22), e2325-e2330 (2023) [10.1212/WNL.0000000000207870]
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Conference Presentation (After Call)
Fully automated and GMP-compliant synthesis of [18F]SynVesT-1 on a Trasis AllinOne module
25th International Symposium on Radiopharmaceutical Sciences, ISRS2023, HonoluluHonolulu, USA, 22 May 2023 - 26 May 2023
[10.34734/FZJ-2024-01119]
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Journal Article
Preparation of NIn-Methyl-6-[18F]fluoro- and 5-Hydroxy-7-[18F]fluorotryptophans as Candidate PET-Tracers for Pathway-Specific Visualization of Tryptophan Metabolism
International journal of molecular sciences 24(20), 15251 (2023) [10.3390/ijms242015251]
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Journal Article
Copper radionuclides for theranostic applications: towards standardisation of their nuclear data. A mini-review
Frontiers in Chemistry 11, 1270351 (2023) [10.3389/fchem.2023.1270351]
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Journal Article
A genetic variation in the adenosine A2A receptor gene contributes to variability in oscillatory alpha power in wake and sleep EEG and A1 adenosine receptor availability in the human brain
NeuroImage 280, 120345 - (2023) [10.1016/j.neuroimage.2023.120345]
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Journal Article
GABAA receptor availability relates to emotion-induced BOLD responses in the medial prefrontal cortex: simultaneous fMRI/PET with [11C]flumazenil
Frontiers in neuroscience 17, 1027697 (2023) [10.3389/fnins.2023.1027697]
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Journal Article
7-[18F]Fluoro-8-azaisatoic Anhydrides: Versatile Prosthetic Groups for the Preparation of PET Tracers
Journal of medicinal chemistry 66(17), 12629−12644 (2023) [10.1021/acs.jmedchem.3c01310]
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Journal Article
Validation of analytical HPLC with post-column injection as a method for rapid and precise quantification of radiochemical yields
Journal of chromatography / B 1228, 123847 - (2023) [10.1016/j.jchromb.2023.123847]
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Poster (After Call)
Quantification of [18F]-SynVesT-1 PET using thin-layer chromatography and image derived input function
The 29th Annual Meeting of the Organization for Human Brain Mapping, OHBM2023, MontréalMontréal, Canada, 22 Jul 2023 - 26 Jul 2023
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Journal Article
AI-based identification of therapeutic agents targeting GPCRs: introducing ligand type classifiers and systems biology
Chemical science 14(32), 8651-8661 (2023) [10.1039/D3SC02352D]
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Journal Article
Reversal of Tau-Dependent Cognitive Decay by Blocking Adenosine A1 Receptors: Comparison of Transgenic Mouse Models with Different Levels of Tauopathy
International journal of molecular sciences 24(11), 9260 - (2023) [10.3390/ijms24119260]
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Journal Article
Cross sections and calculated yields of some radionuclides of yttrium, strontium and rubidium formed in proton-induced reactions on enriched strontium-86: possibility of production of 85gSr, 83Rb and 82mRb in no-carrier-added form
Radiochimica acta 111(2), 81 - 90 (2023) [10.1515/ract-2022-0086]
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Journal Article
Mutated Isocitrate Dehydrogenase (mIDH) as Target for PET Imaging in Gliomas
Molecules 28(7), 2890 (2023) [10.3390/molecules28072890]
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Journal Article
Evaluation of the 18F-Labeled Analog of the Therapeutic All-d-enantiomeric Peptide RD2 for Amyloid β Imaging
European journal of pharmaceutical sciences 184, 106421 (2023) [10.1016/j.ejps.2023.106421]
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Journal Article
Additive value of [18F]PI-2620 perfusion imaging in progressive supranuclear palsy and corticobasal syndrome
European journal of nuclear medicine and molecular imaging 50(2), 423 - 434 (2023) [10.1007/s00259-022-05964-w]
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Journal Article
Next Generation Copper Mediators for the Efficient Production of 18 F‐Labeled Aromatics
Chemistry - a European journal 29(2), e202202965 (2023) [10.1002/chem.202202965]
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Conference Presentation (After Call)
F-18-ALX5406: Eine hirngängige Prodrug zur PET-Bildgebung des Glycintransporters Typ 1
60. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, LeipzigLeipzig, Germany, 27 Apr 2022 - 30 Apr 2022
[10.1055/s-0042-1745960]
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Conference Presentation (After Call)
Radiosynthese von [18F]FS-DPA mittels SuFEx-Clickchemie und präklinische Evaluation im Schlaganfallmodell
60. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, LeipzigLeipzig, Germany, 27 Apr 2022 - 30 Apr 2022
[10.1055/s-0042-1745967]
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Conference Presentation (After Call)
Ein Zr-89-markierter PSMA-Tracer (Zr-89-PSMA-DFO) zur PET/CT bei Patienten mit schwacher PSMA-Expression des rezidivierten Prostatakarzinoms
60. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, LeipzigLeipzig, Germany, 27 Apr 2022 - 30 Apr 2022
[10.1055/s-0042-1745976]
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Conference Presentation (After Call)
Differential correlation of the BOLD response to different types of emotional valence processing with the availability of GABAA receptors: A combined fMRI and [11C]flumazenil-PET study
60. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, LeipzigLeipzig, Germany, 27 Apr 2022 - 30 Apr 2022
[10.1055/s-0042-1745985]
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Conference Presentation (After Call)
A1 adenosine receptor occupancy and availability after 5-day regular coffee consumption and subsequent abstention
60. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, LeipzigLeipzig, Germany, 27 Apr 2022 - 30 Apr 2022
[10.1055/s-0042-1746012]
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Conference Presentation (After Call)
Avian neurons consume three times less glucose compared to mammals
60. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, LeipzigLeipzig, Germany, 27 Apr 2022 - 30 Apr 2022
[10.1055/s-0042-1746135]
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Conference Presentation (After Call)
52gMn(II)-Labelled PSMA-ligands as bimodal PET/MR imaging probes
24th International Symposium on Radiopharmaceutical Sciences, ISRS2022, NantesNantes, France, 29 May 2022 - 3 Jun 2022
(2022) [10.1016/S0969-8051(22)00335-3]
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Conference Presentation (After Call)
Convenient preparation of 18F-labeled human insulin by Pd-catalyzed S-arylation
24th International Symposium on Radiopharmaceutical Sciences, ISRS2022, NantesNantes, France, 29 May 2022 - 3 Jun 2022
(2022) [10.1016/S0969-8051(22)00259-1]
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Conference Presentation (After Call)
Evaluation of a multifunctional blood-brain barrier co-culture model prepared from rat primary brain endothelial cells and astrocytes: first results
24th International Symposium on Radiopharmaceutical Sciences, ISRS2022, NantesNantes, France, 29 May 2022 - 3 Jun 2022
(2022) [10.1016/S0969-8051(22)00233-5]
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Conference Presentation (After Call)
Preparation of 5-[18F],7-difluoro- and 5,7-[18F]difluorotryptophans
24th International Symposium on Radiopharmaceutical Sciences, ISRS2022, NantesNantes, France, 29 May 2022 - 3 Jun 2022
(2022) [10.1016/S0969-8051(22)00110-X]
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Conference Presentation (After Call)
8-Bicycloalkyl-CPFPX derivatives as potent and selective tools for PET imaging of the A1 adenosine receptor
24th International Symposium on Radiopharmaceutical Sciences, ISRS2022, NantesNantes, France, 29 May 2022 - 3 Jun 2022
(2022) [10.1016/S0969-8051(22)00096-8]
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Journal Article
Avian neurons consume three times less glucose than mammalian neurons
Current biology 32(19), 4306 - 4313.e4 (2022) [10.1016/j.cub.2022.07.070]
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Journal Article/Contribution to a conference proceedings
Fragmentation of functional resting state networks in a transgenic mouse model of tau pathology
30th International Symposium on Cerebral Blood Flow, Metabolism and Function (BRAIN) in conjunction with the 15th International Conference on Quantification of Brain Function with PET (BRAIN PET), GlasgowGlasgow, Scotland, 20 Jun 2022 - 20 Jun 2022
Journal of cerebral blood flow & metabolism 42(1_SUPPL), 73 (2022) special issue: "SI"
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Journal Article
Assessment of the In Vivo Relationship Between Cerebral Hypometabolism, Tau Deposition, TSPO Expression, and Synaptic Density in a Tauopathy Mouse Model: a Multi-tracer PET Study
Molecular neurobiology 59(6), 3402 - 3413 (2022) [10.1007/s12035-022-02793-8]
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Conference Presentation (After Call)
Application of quaternary 1,4-diazabicyclo[2.2.2]octan (DABCO) salts for SN2 “minimalist” radiofluorination
24th International Symposium on Radiopharmaceutical Sciences, iSRS 2022, NantesNantes, France, 29 May 2022 - 3 Jun 2022
(2022) [10.1016/S0969-8051(22)00134-2]
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Conference Presentation (After Call)
Does repeated coffee consumption during chronic sleep restriction affect A1 adenosine receptor availability in humans?
The 26th Conference of the European Sleep Research Society, Sleep Europe 2022, AthensAthens, Greece, 27 Sep 2022 - 30 Sep 2022
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Poster (After Call)
Does repeated coffee consumption during chronic sleep restriction affect A1 adenosine receptor availability in humans?
The 26th Conference of the European Sleep Research Society, Sleep Europe 2022, AthensAthens, Greece, 27 Sep 2022 - 30 Sep 2022
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Conference Presentation (Other)
18F-Labelled probes for non-invasive assessment of the IDH genotype in glioma patients
60. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, LeipzigLeipzig, Germany, 27 Apr 2022 - 30 Apr 2022
[10.1055/s-0042-1746026]
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Conference Presentation (After Call)
[18F]ALX5406: a brain-penetrating prodrug for GlyT1-specific PET imaging
24th International Symposium on Radiopharmaceutical Sciences, iSRS 2022, NantesNantes, Germany, 29 May 2022 - 3 Jun 2022
(2022) [10.1016/S0969-8051(22)00127-5]
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Conference Presentation (After Call)
[18F]FS-DPA: a novel PET probe for imaging of neuroinflammation easily accessible via SuFEx click labeling
24th International Symposium on Radiopharmaceutical Sciences, iSRS 2022, NantesNantes, Germany, 29 May 2022 - 3 Jun 2022
(2022) [10.1016/S0969-8051(22)00247-5]
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Conference Presentation (Invited)
Radiosynthesis and biological evaluation of [18F]R91150, a selective 5-HT2A receptor antagonistfor PET imaging
DPhG Annual Meeting 2022, DPhG 2022, MarburgMarburg, Germany, 14 Sep 2022 - 16 Sep 2022
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Journal Article
An 89Zr-Labeled PSMA Tracer for PET/CT Imaging of Prostate Cancer Patients
Journal of nuclear medicine 63(4), 573 - 583 (2022) [10.2967/jnumed.121.262290]
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Conference Presentation (After Call)
Fully automated and GMP-compliant synthesis of [18F]JK-PSMA-7 on a Trasis AllinOne module
24th International Symposium on Radiopharmaceutical Sciences, iSRS 2022, NantesNantes, France, 29 May 2022 - 3 Jun 2022
(2022) [10.1016/S0969-8051(22)00273-6]
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Journal Article
The role of chemistry in accelerator-based production and separation of radionuclides as basis for radiolabelled compounds for medical applications
Radiochimica acta 110(6-9), 707 - 724 (2022) [10.1515/ract-2022-0017]
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Conference Presentation (After Call)
18F-labelled probes for non-invasive assessment of the IDH genotype in diffuse glioma
24th International Symposium on Radiopharmaceutical Sciences, iSRS 2022, NantesNantes, France, 29 May 2022 - 3 Jun 2022
(2022) [10.1016/S0969-8051(22)00081-6]
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Journal Article
Two Decades of Brain Tumour Imaging with O-(2-[18F]fluoroethyl)-L-tyrosine PET: The Forschungszentrum Jülich Experience
Cancers 14(14), 3336 - (2022) [10.3390/cancers14143336]
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Journal Article
Convenient PET-tracer production via SuFEx 18F-fluorination of nanomolar precursor amounts
European journal of medicinal chemistry 237, 114383 (2022) [10.1016/j.ejmech.2022.114383]
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Journal Article
Excitation functions of proton-induced nuclear reactions on 86Sr, with particular emphasis on the formation of isomeric states in86Y and 85Y
The European physical journal / A 58(4), 67 (2022) [10.1140/epja/s10050-022-00714-w]
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Journal Article
Cyclotrons Operated for Nuclear Medicine and Radiopharmacy in the German Speaking D-A-CH Countries: An Update on Current Status and Trends
Frontiers in nuclear medicine 2, 850414 (2022) [10.3389/fnume.2022.850414]
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Positron Emission Intensity in the Decay of 86gY for Use in Dosimetry Studies
Molecules 27(3), 768 - (2022) [10.3390/molecules27030768]
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Journal Article
mGluR 5 and GABA A receptor‐specific parametric PET atlas construction— PET / MR data processing pipeline, validation, and application
Human brain mapping 43(7), 2148-2163 (2022) [10.1002/hbm.25778]
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Journal Article
mGluR5 binding changes during a mismatch negativity task in a multimodal protocol with [11C]ABP688 PET/MR-EEG
Translational Psychiatry 12(1), 6 (2022) [10.1038/s41398-021-01763-3]
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Journal Article
Translational Development of a Zr-89-Labeled Inhibitor of Prostate-specific Membrane Antigen for PET Imaging in Prostate Cancer
Molecular imaging & biology 24, 115-125 (2022) [10.1007/s11307-021-01632-x]
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Journal Article
Imaging of cerebral tryptophan metabolism using 7-[18F]FTrp-PET in a unilateral Parkinsonian rat model
NeuroImage 247, 118842 - (2022) [10.1016/j.neuroimage.2021.118842]
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Journal Article
Psilocybin targets a common molecular mechanism for cognitive impairment and increased craving in alcoholism
Science advances 7(47), eabh2399 (2021) [10.1126/sciadv.abh2399]
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Evaluation of 3-l- and 3-d-[18F]Fluorophenylalanines as PET Tracers for Tumor Imaging
Cancers 13(23), 6030 - (2021) [10.3390/cancers13236030]
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Journal Article
Binding characteristics of [ 18 F]PI-2620 distinguish the clinically predicted tau isoform in different tauopathies by PET
Journal of cerebral blood flow & metabolism 41(11), 2957 - 2972 (2021) [10.1177/0271678X211018904]
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Cerebral A1 adenosine receptor availability in female and male participants and its relationship to sleep
NeuroImage 245, 118695 - (2021) [10.1016/j.neuroimage.2021.118695]
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Journal Article
Feasibility of short imaging protocols for [18F]PI-2620 tau-PET in progressive supranuclear palsy
European journal of nuclear medicine and molecular imaging 48(12), 3872 - 3885 (2021) [10.1007/s00259-021-05391-3]
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Drug Penetration into the Central Nervous System: Pharmacokinetic Concepts and In Vitro Model Systems
Pharmaceutics 13(10), 1542 - (2021) [10.3390/pharmaceutics13101542]
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[18F]ALX5406: A Brain-Penetrating Prodrug for GlyT1-Specific PET Imaging
ACS chemical neuroscience 12(18), 3335 - 3346 (2021) [10.1021/acschemneuro.1c00284]
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18F-Labeled magnetic nanovectors for bimodal cellular imaging
Biomaterials science 9(13), 4717 - 4727 (2021) [10.1039/D1BM00616A]
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Production of 6-L-[18F]Fluoro-m-tyrosine in an Automated Synthesis Module for 11C-Labeling
Molecules 26(18), 5550 (2021) [10.3390/molecules26185550]
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Conference Presentation (After Call)
Radiosynthesis and biological evaluation of [18F]R91150, a selective 5-HT2A receptor antagonist for PET imaging
Society of Radiopharmaceutical Sciences Virtual Meeting, eSRS, virtuellvirtuell, USA, 17 May 2021 - 19 May 2021
(2021)
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[18F]-JK-PSMA-7 PET/CT Under Androgen Deprivation Therapy in Advanced Prostate Cancer
Molecular imaging and biology 23(2), 277-286 (2020) [10.1007/s11307-020-01546-0]
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On the consensus nomenclature rules for radiopharmaceutical chemistry – Reconsideration of radiochemical conversion
Nuclear medicine and biology 93, 19 - 21 (2021) [10.1016/j.nucmedbio.2020.11.003]
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Journal Article
Production Cross-Section Measurements for Terbium Radionuclides of Medical Interest Produced in Tantalum Targets Irradiated by 0.3 to 1.7 GeV Protons and Corresponding Thick Target Yield Calculations
Frontiers in medicine 8, 625561 (2021) [10.3389/fmed.2021.625561]
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Journal Article
Möglichkeiten und Grenzen der Nutzung kleiner Zyklotrone bei der Produktion medizinisch relevanter Radionuklide
Der Nuklearmediziner 44(02), 120 - 126 (2021) [10.1055/a-1380-7815]
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Towards chronic deep brain stimulation in freely moving hemiparkinsonian rats: applicability and functionality of a fully implantable stimulation system
Journal of neural engineering 18(3), 036018 (2021) [10.1088/1741-2552/abe806]
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Continuing Nuclear Data Research for Production of Accelerator-Based Novel Radionuclides for Medical Use: A Mini-Review
Frontiers in physics 9, 639290 (2021) [10.3389/fphy.2021.639290]
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Journal Article
Radiosynthesis and Biological Evaluation of [18F]R91150, a Selective 5-HT2A Receptor Antagonist for PET-Imaging
ACS medicinal chemistry letters 12(5), 738 - 744 (2021) [10.1021/acsmedchemlett.0c00658]
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Journal Article
One-Stop Shop: 18 F-Flortaucipir PET Differentiates Amyloid-Positive and -Negative Forms of Neurodegenerative Diseases
Journal of nuclear medicine 62(2), 240 - 246 (2021) [10.2967/jnumed.120.244061]
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Journal Article
Rapid 18 F-labeling via Pd-catalyzed S -arylation in aqueous medium
Chemical communications 57, 3547-3550 (2021) [10.1039/D1CC00745A]
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Journal Article
Design, synthesis and biological evaluation of Tozadenant analogues as adenosine A2A receptor ligands
European journal of medicinal chemistry 214, 113214 (2021) [10.1016/j.ejmech.2021.113214]
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Journal Article
Species Differences in Microsomal Metabolism of Xanthine-Derived A1 Adenosine Receptor Ligands
Pharmaceuticals 14(3), 277 - (2021) [10.3390/ph14030277]
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Journal Article
Excitatory–inhibitory balance within EEG microstates and resting-state fMRI networks: assessed via simultaneous trimodal PET–MR–EEG imaging
Translational Psychiatry 11(1), 60 (2021) [10.1038/s41398-020-01160-2]
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Journal Article
Delivery of the Radionuclide 131I Using Cationic Fusogenic Liposomes as Nanocarriers
International journal of molecular sciences 22(1), 457 - (2021) [10.3390/ijms22010457]
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Journal Article
Radiosynthesis and evaluation of 18F-labeled dopamine D4-receptor ligands
Nuclear medicine and biology 92, 43-52 (2021) [10.1016/j.nucmedbio.2020.07.004]
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Finding new communities: A principle of neuronal network reorganization in Alzheimer’s disease.
Brain Connectivity 11(3), 225-238 (2021) [10.1089/brain.2020.0889]
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Journal Article
Positron-Emission-Tomography Imaging of Long-Term Expression of the 18kDa Translocator Protein After Sudden Cardiac Arrest in Rats
Shock 55(5), 620-629 (2021) [10.1097/SHK.0000000000001546]
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Journal Article
Dnmt3a2/Dnmt3L Overexpression in the Dopaminergic System of Mice Increases Exercise Behavior through Signaling Changes in the Hypothalamus
International journal of molecular sciences 21(17), 6297 - (2020) [10.3390/ijms21176297]
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ADORA2A variation and adenosine A1 receptor availability in the human brain with a focus on anxiety-related brain regions: modulation by ADORA1 variation
Translational Psychiatry 10(1), 406 (2020) [10.1038/s41398-020-01085-w]
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Journal Article
Preparation of 5-[131I]iodotubercidin for the detection of adenosine kinase
Journal of radioanalytical and nuclear chemistry 326(3), 1691 - 1697 (2020) [10.1007/s10967-020-07465-2]
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Journal Article
Assessment of 18 F-PI-2620 as a Biomarker in Progressive Supranuclear Palsy
JAMA neurology 77(11), 1408 - (2020) [10.1001/jamaneurol.2020.2526]
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Journal Article
Nuclear Medicine in Times of COVID-19: How Radiopharmaceuticals Could Help to Fight the Current and Future Pandemics
Pharmaceutics 12(12), 1247 (2020) [10.3390/pharmaceutics12121247]
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Journal Article
Entorhinal Tau Predicts Hippocampal Activation and Memory Deficits in Alzheimer’s Disease
Journal of Alzheimer's disease 78(4), 1601-1614 (2020) [10.3233/JAD-200835]
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Journal Article
Accurate determination of production data of the non-standard positron emitter 86Y via the 86Sr(p,n)-reaction
Radiochimica acta 108(9), 747 - 756 (2020) [10.1515/ract-2020-0021]
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Journal Article
Thermochromatographic separation of 45Ti and subsequent radiosynthesis of [45Ti]salan
Journal of radioanalytical and nuclear chemistry 326, 1281–1287 (2020) [10.1007/s10967-020-07376-2]
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Journal Article
Preparation of labeled aromatic amino acids via late-stage 18 F-fluorination of chiral nickel and copper complexes
Chemical communications 56(66), 9505 - 9508 (2020) [10.1039/D0CC02223C]
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Journal Article
11C- and 18F-labelled tryptophans as PET-tracers for imaging of altered tryptophan metabolism in age-associated disorders
Russian chemical reviews 89(9), 879 - 896 (2020) [10.1070/RCR4954]
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Bolus infusion scheme for the adjustment of steady state [11C]Flumazenil levels in the grey matter and in the blood plasma for neuroreceptor imaging
NeuroImage 221, 117160 - (2020) [10.1016/j.neuroimage.2020.117160]
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Journal Article
High uptake of 68Ga-PSMA and 18F-DCFPyL in the peritumoral area of rat gliomas due to activated astrocytes
EJNMMI Research 10(1), 55 (2020) [10.1186/s13550-020-00642-0]
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Development and Evaluation of a Versatile Receptor-Ligand Binding Assay Using Cell Membrane Preparations Embedded in an Agarose Gel Matrix and Evaluation with the Human Adenosine A1 Receptor
Assay and drug development technologies 18(7), (2020) [10.1089/adt.2020.991]
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Journal Article
Intraindividual Comparison of 18 F-PSMA-1007 with Renally Excreted PSMA Ligands for PSMA PET Imaging in Patients with Relapsed Prostate Cancer
Journal of nuclear medicine 61(5), 729 - 734 (2020) [10.2967/jnumed.119.234898]
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Preparation of a First 18F-Labeled Agonist for M1 Muscarinic Acetylcholine Receptors
Molecules 25(12), 2880 - (2020) [10.3390/molecules25122880]
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Journal Article
Investigation of Cerebral O-(2-[$^{18}$F]Fluoroethyl)-L-Tyrosine Uptake in Rat Epilepsy Models
Molecular imaging & biology 22, 1255–1265 (2020) [10.1007/s11307-020-01503-x]
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Journal Article
In-vivo Tierversuchsersatzmodell zur präklinischen Tumordiagnostik: PET-MR im Hühnerembryo
NuklearMedizin 2020, LeipzigLeipzig, 6 Jul 2020 - 9 Jul 2020
Nuklearmedizin 59(02), 176 (2020) [10.1055/s-0040-1708380]
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Early-phase [18F]PI-2620 tau-PET imaging as a surrogate marker of neuronal injury
European journal of nuclear medicine and molecular imaging 47, 2911–2922 (2020) [10.1007/s00259-020-04788-w]
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Journal Article
An 18 F-Labeled PSMA Ligand for PET/CT of Prostate Cancer: First-in-Humans Observational Study and Clinical Experience with 18 F-JK-PSMA-7 During the First Year of Application
Journal of nuclear medicine 61(2), 202 - 209 (2020) [10.2967/jnumed.119.229542]
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mGluR5 receptor availability is associated with lower levels of negative symptoms and better cognition in male patients with chronic schizophrenia
Human brain mapping 41(10), 2762-2781 (2020) [10.1002/hbm.24976]
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Journal Article
Prediction of survival in patients with IDH-wildtype astrocytic gliomas using dynamic O-(2-[18F]-fluoroethyl)-l-tyrosine PET
European journal of nuclear medicine and molecular imaging 47, 1486–1495 (2020) [10.1007/s00259-020-04695-0]
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Journal Article
Measurement of spallation cross sections for the production of terbium radioisotopes for medical applications from tantalum targets
Nuclear instruments & methods in physics research / B Beam interactions with materials and atoms Section B 463, 327 - 329 (2020) [10.1016/j.nimb.2019.04.071]
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Journal Article
Image-Derived Input Functions for Quantification of A1 Adenosine Receptors Availability in Mice Brains Using PET and [18F]CPFPX
Frontiers in physiology 10, 1617 (2020) [10.3389/fphys.2019.01617]
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Flare phenomenon in O-(2-[ 18 F]-Fluoroethyl)-L-Tyrosine PET after resection of gliomas
Journal of nuclear medicine 61(9), 1294-1299 (2020) [10.2967/jnumed.119.238568]
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Journal Article
Influence of binding affinity and blood plasma level on cerebral pharmacokinetics and PET imaging characteristics of two novel xanthine PET radioligands for the A1 adenosine receptor
Nuclear medicine and biology 82-83, 1 - 8 (2020) [10.1016/j.nucmedbio.2019.12.001]
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Journal Article
Comparison of [18F]Fluoroethyltyrosine PET and Sodium MRI in Cerebral Gliomas: a Pilot Study
Molecular imaging & biology 22(-), 198–207 (-) [10.1007/s11307-019-01349-y]
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Conference Presentation (After Call)
Novel 18F-labeled D4-receptor ligands
DPhG Annual Meeting 2019, HeidelbergHeidelberg, Germany, 1 Sep 2019 - 4 Sep 2019
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Conference Presentation (Invited)
Impact of emerging radiofluorination methods on preclinical and clinical PET imaging
Danish Radiochemistry Meeting, LundLund, Sweden, 21 Mar 2019 - 22 Mar 2019
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Conference Presentation (After Call)
Thermochromatographische Isolierung von 45Ti aus einem mit 16 MeV Protonen bestrahlten Sc-Target
Jahrestagung der Fachgruppe Nuklearchemie der Gesellschaft Deutscher Chemiker, DresdenDresden, Germany, 25 Sep 2019 - 27 Sep 2019
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Conference Presentation (After Call)
52gMn-Markierte PSMA-spezifische Liganden als Vorstufe für bimodale PET/MR Tracer
Jahrestagung der Fachgruppe Nuklearchemie der Gesellschaft Deutscher Chemiker, DresdenDresden, Germany, 25 Sep 2019 - 27 Sep 2019
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Conference Presentation (After Call)
Thermochromatographic isolation of 45Ti from irradiated Sc
2nd International Conference on Radioanalytical and Nuclear Chemistry, BudapestBudapest, Hungary, 5 May 2019 - 10 May 2019
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Conference Presentation (Invited)
Radiochemical Methods in Radionuclide Production at a Cyclotron
2nd International Conference on Radioanalytical and Nuclear Chemistry, BudapestBudapest, Hungary, 5 May 2019 - 10 May 2019
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Conference Presentation (Invited)
Impact of emerging radiofluorination methods on preclinical and clinical PET imaging
2nd International Conference on Radioanalytical and Nuclear Chemistry, BudapestBudapest, Hungary, 5 May 2019 - 10 May 2019
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Journal Article
The efficient preparation of radiolabeled aromatic amino acids via Cu‐mediated radiofluorination of Ni‐complexes
The 23rd International Symposium on Radiopharmaceutical Sciences, ISRS 2019, BeijingBeijing, China, 26 May 2019 - 31 May 2019
Journal of labelled compounds and radiopharmaceuticals 62(S1), S118 (2019)
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Conference Presentation (After Call)
2‐[18F]Fluoro‐5‐iodopyridine ([18F]FIPy): A novel reactive prosthetic group for the fast site specific radiolabeling via Pd‐catalyzed cross coupling reactions
The 23rd International Symposium on Radiopharmaceutical Sciences, BeijingBeijing, China, 26 May 2019 - 31 May 2019
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Conference Presentation (After Call)
Preparation of [18F]fluoroalkenyliodonium salts and their application for radiolabeling by cross‐coupling reactions
The 23rd International Symposium on Radiopharmaceutical Sciences, BeijingBeijing, China, 26 May 2019 - 31 May 2019
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Journal Article
Positron-emitting radionuclides for applications, with special emphasis on their production methodologies for medical use
Radiochimica acta 107(9-11), 1011 - 1026 (2019) [10.1515/ract-2019-3154]
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Conference Presentation (After Call)
The Efficient Preparation of Radiolabeled Aromatic Amino Acids via Cu-Mediated Radiofluorination using Ni-complexes
57. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, NuklearMedizin 2019, BremenBremen, Germany, 3 Apr 2019 - 6 Apr 2019
[10.1055/s-0039-1683568]
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Conference Presentation (After Call)
Synthesis of N-methyl- and 5-HO-[18F]fluorotryptophans
57. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, NuklearMedizin 2019, BremenBremen, Germany, 3 Apr 2019 - 6 Apr 2019
[10.1055/s-0039-1683491]
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Conference Presentation (After Call)
Modulation of brain network recruitment caused by STN DBS and L-DOPA in parkinsonian rats
57. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, NuklearMedizin 2019, Universität zu KölnBremen, Universität zu Köln, Germany, 3 Apr 2019 - 6 Apr 2019
[10.1055/s-0039-1683629]
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Conference Presentation (After Call)
Verändert F-18 PSMA-1007 im Vergleich zu Ga-68 PSMA-11 oder F-18 DCFPyL die Befundsicherheit der PET/CT im biochemischen Rezidiv des Prostatakarzinoms?
57. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, NuklearMedizin 2019, Universität zu KölnBremen, Universität zu Köln, Germany, 3 Apr 2019 - 6 Apr 2019
[10.1055/s-0039-1683609]
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Conference Presentation (After Call)
18F-Markierung von Phenylpiperazinen in ortho-Position als neues Strukturmotiv in der Entwicklung spezifischer D4R-Radioliganden als PET-Tracer.
57. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, NuklearMedizin 2019, BremenBremen, Germany, 3 Apr 2019 - 6 Apr 2019
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Conference Presentation (After Call)
Discovery of [18F]JK-PSMA-7 as PET-probe suitable for imaging of small PSMA expressing lesions
The 23rd International Symposium on Radiopharmaceutical Sciences, ISRS 2019, Universität zu KölnBeijing, Universität zu Köln, China, 26 May 2019 - 31 May 2019
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Conference Presentation (After Call)
A novel 18F-labeled D4-receptor ligand
The 23rd International Symposium on Radiopharmaceutical Sciences, ISRS 2019, BeijingBeijing, China, 26 May 2019 - 31 May 2019
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Conference Presentation (After Call)
Preparation of 18F-labeled aromatic amino acids by copper-mediated radiofluorination
The 23rd International Symposium on Radiopharmaceutical Sciences (ISRS 2019), BeijingBeijing, China, 26 May 2019 - 31 May 2019
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Poster (After Call)
Novel 18F-labeled D4-receptor ligands
DPhG Annual Meeting 2019, HeidelbergHeidelberg, Germany, 1 Sep 2019 - 3 Sep 2019
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Journal Article
Alcohol-Supported Cu-Mediated 18F-Fluorination of Iodonium Salts under “Minimalist” Conditions
Molecules 24(17), 3197 (2019) [10.3390/molecules24173197]
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Journal Article
Biodistribution and radiation dosimetry of [18F]-JK-PSMA-7 as a novel prostate-specific membrane antigen-specific ligand for PET/CT imaging of prostate cancer
EJNMMI Research 9(1), 66 (2019) [10.1186/s13550-019-0540-7]
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Journal Article
Spatial distributions of cholinergic impairment and neuronal hypometabolism differ in MCI due to AD
NeuroImage: Clinical 24, 101978 - (2019) [10.1016/j.nicl.2019.101978]
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Journal Article
Minimalist approach meets green chemistry: Synthesis of 18F-labeled (hetero)aromatics in pure ethanol
Journal of labelled compounds and radiopharmaceuticals 62(8), 404 - 410 (2019) [10.1002/jlcr.3776]
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Journal Article
Peripheral ganglia in healthy rats as target structures for the evaluation of PSMA imaging agents
BMC cancer 19(1), 633 (2019) [10.1186/s12885-019-5841-8]
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Journal Article
Level of education mitigates the impact of tau pathology on neuronal function
European journal of nuclear medicine and molecular imaging 46(9), 1787–1795 (2019) [10.1007/s00259-019-04342-3]
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Journal Article
Effects of subthalamic deep brain stimulation on striatal metabolic connectivity in a rat hemiparkinsonian model
Disease models & mechanisms 12(5), dmm039065 - (2019) [10.1242/dmm.039065]
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Journal Article
Discovery of 18F-JK-PSMA-7, a PET Probe for the Detection of Small PSMA-Positive Lesions
Journal of nuclear medicine 60(6), 817 - 823 (2019) [10.2967/jnumed.118.218495]
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Contribution to a book
The Radiopharmaceutical Chemistry of Fluorine-18: Nucleophilic Fluorinations
Radiopharmaceutical Chemistry / Lewis, Jason S. (Editor) , Chapter 15 ; ISBN: 978-3-319-98946-4 ; doi:10.1007/978-3-319-98947-1
Cham : Springer International Publishing 273-283 (2019) [10.1007/978-3-319-98947-1_15]
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Journal Article
Simultaneous PET-MR-EEG: Technology, Challenges and Application in Clinical Neuroscience
IEEE transactions on radiation and plasma medical sciences 3(3), 377 - 385 (2019) [10.1109/TRPMS.2018.2886525]
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Journal Article
Relevance of In Vitro Metabolism Models to PET Radiotracer Development: Prediction of In Vivo Clearance in Rats from Microsomal Stability Data
Pharmaceuticals 12(2), 57 (2019) [10.3390/ph12020057]
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Journal Article
52g/55Mn-Labelled CDTA-based trimeric complexes as novel bimodal PET/MR probes with high relaxivity
Dalton transactions 48(9), 3003 - 3008 (2019) [10.1039/C8DT04996C]
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Journal Article
2-[18F]Fluorophenylalanine: Synthesis by Nucleophilic 18F-Fluorination and Preliminary Biological Evaluation
Synthesis 51(03), 664 - 676 (2019) [10.1055/s-0037-1611370]
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Journal Article
Influence of incubation conditions on microsomal metabolism of xanthine-derived A1 adenosine receptor ligands
Journal of pharmacological & toxicological methods 95, 16 - 26 (2019) [10.1016/j.vascn.2018.11.005]
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Journal Article
FET PET reveals considerable spatial differences in tumour burden compared to conventional MRI in newly diagnosed glioblastoma.
European journal of nuclear medicine and molecular imaging 46(3), 591-602 (2019) [10.1007/s00259-018-4188-8]
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Journal Article
Influence of Dexamethasone on O-(2-[18F]-Fluoroethyl)-l-Tyrosine Uptake in the Human Brain and Quantification of Tumor Uptake
Molecular imaging & biology 21(1), 168–174 (2019) [10.1007/s11307-018-1221-z]
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Journal Article
Uptake in non-affected bone tissue does not differ between [18F]-DCFPyL and [68Ga]-HBED-CC PSMA PET/CT
PLOS ONE 13(12), e0209613 - (2018) [10.1371/journal.pone.0209613]
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Contribution to a book
Chapter 20, Part E: Radiotracers for PET and MR-PET Imaging
-Hybrid MR-PET Imaging: Systems, Methods and Applications / Shah, N Jon (Editor); Cambridge : Royal Society of Chemistry, 2018, ; ISBN: ; doi:10.1039/9781788013062
Cambridge : Royal Society of Chemistry, New Developments in NMR 381-399 (2018)
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Journal Article
New developments in the production of theranostic pairs of radionuclides
Journal of radioanalytical and nuclear chemistry 318(3), 1493 - 1509 (2018) [10.1007/s10967-018-6238-x]
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Journal Article
Role of Extracellular Loops and Membrane Lipids for Ligand Recognition in the Neuronal Adenosine Receptor Type 2A: An Enhanced Sampling Simulation Study
Molecules 23(10), 2616 - (2018) [10.3390/molecules23102616]
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Journal Article
Structural Prediction of the Dimeric Form of the Mammalian Translocator Membrane Protein TSPO: A Key Target for Brain Diagnostics
International journal of molecular sciences 19(9), 2588 - (2018) [10.3390/ijms19092588]
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Journal Article
Predicting IDH genotype in gliomas using FET PET radiomics
Scientific reports 8(1), 13328 (2018) [10.1038/s41598-018-31806-7]
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Poster (Other)
Tau pathology networks associated with functional connectivity networks and disease progression in Alzheimer’s disease
Human Amyloid Imaging Meeting, Miami, FloridaMiami, Florida, USA, 17 Jan 2018 - 19 Jan 2018
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Poster (Other)
Level of Brain Reserve Associated with Spatial Extent of Tau-Neurodegeneration Pattern in Alzheimer’s Disease
Alzheimer's Association International Conference (AAIC) 2018, ChicagoChicago, USA, 22 Jul 2018 - 26 Jul 2018
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Conference Presentation (Invited)
Are the effects of Tau pathology on glucose metabolism mitigated by the level of education?
7th European Conference on Clinical Neuroimaging (ECCN), BrüsselBrüssel, Belgien, 26 Mar 2018 - 27 Mar 2018
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Journal Article
Combined FET PET/MRI radiomics differentiates radiation injury from recurrent brain metastasis
NeuroImage: Clinical 20, 537 - 542 (2018) [10.1016/j.nicl.2018.08.024]
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Journal Article
In vivo Molecular Imaging of Glutamate Carboxypeptidase II Expression in Re-endothelialisation after Percutaneous Balloon Denudation in a Rat Model
Scientific reports 8(1), 7411 (2018) [10.1038/s41598-018-25863-1]
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Journal Article
Heinz H. Coenen - A pioneer in the field of nuclear and radiochemistry
Journal of labelled compounds and radiopharmaceuticals 61(3), 122 - 123 (2018) [10.1002/jlcr.3599]
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Journal Article
Investigation of cis-4-[18F]Fluoro-D-Proline Uptake in Human Brain Tumors After Multimodal Treatment
Molecular imaging & biology 20(6), 1035–1043 (2018) [10.1007/s11307-018-1197-8]
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Conference Presentation (Invited)
Preparation of radioactive imaging agents and their application in clinical practice
Future Biotech Winter Retreat, SochiSochi, Russland, 21 Jan 2018 - 27 Jan 2018
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Journal Article
Isolation of high purity 73Se using solid phase extraction after selective 4,5-[73Se]benzopiazselenol formation with aminonaphthalene
Radiochimica acta 106(6), 497–505 (2018) [10.1515/ract-2017-2864]
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Journal Article
Discovery of 7-[ 18 F]Fluorotryptophan as a Novel Positron Emission Tomography (PET) Probe for the Visualization of Tryptophan Metabolism in Vivo
Journal of medicinal chemistry 61(1), 189 - 206 (2018) [10.1021/acs.jmedchem.7b01245]
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Journal Article
Networks of tau distribution in Alzheimer’s disease
Brain 141(2), 568–581 (2018) [10.1093/brain/awx353]
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Journal Article
Effect of cholinergic treatment depends on cholinergic integrity in early Alzheimer’s disease
Brain 141(3), 903–915 (2018) [10.1093/brain/awx356]
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Journal Article
Static and dynamic 18F–FET PET for the characterization of gliomas defined by IDH and 1p/19q status
European journal of nuclear medicine and molecular imaging 45(3), 443–451 (2018) [10.1007/s00259-017-3846-6]
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Contribution to a conference proceedings/Contribution to a book
New irradiation facilities for development of production methods of medical radionuclides at cyclotrons at Forschungszentrum Jülich
16th International Workshop on Targetry an Target Chemistry, Snata FeSnata Fe, USA, 29 Aug 2016 - 1 Sep 2016
Melville, NY : Inst., AIP conference proceedings 1845, 020020 pp. (2017) [10.1063/1.4983551]
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Contribution to a book
Production of medically useful bromine isotopes via alpha-particle induced nuclear reactions
Les Ulis : EDP Sciences, The @European physical journal / Web of Conferences 146, 08006 pp. (2017) [10.1051/epjconf/201714608006]
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Conference Presentation (Invited)
Radioactive imaging agents: powerful tools also in your clinical practice?
9th Missing link IN TRANSLATIONAL SCIENCE SEMINAR, KölnKöln, Deutschland, 14 Sep 2017 - 14 Sep 2017
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Conference Presentation (Invited)
Radioactive imaging agents: powerful tools also in your clinical practice?
9th Missing link IN TRANSLATIONAL SCIENCE SEMINAR, KölnKöln, Deutschland, 14 Sep 2017 - 14 Sep 2017
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Conference Presentation (Invited)
PET Tracer development at Jülich
SMART|AtmoSim_Lab Opening, TbilisiTbilisi, Georgien, 28 Sep 2017 - 3 Oct 2017
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Conference Presentation (Invited)
The production of PET tracers for the diagnosis of oncological and neurological diseases
2. 1st Palestinian International Conference On Peaceful Usage Of Atomic Energy, PalestinePalestine, Israel, 17 Feb 2017 - 20 Feb 2017
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Conference Presentation (Invited)
TAU TRACER: Was können sie und wann sind sie einsetzbar?
OGNMB Kongress, Zell am SeeZell am See, Österreich, 18 Jan 2017 - 24 Jan 2017
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Journal Article
Convenient Preparation of 18F-Labeled Peptide Probes for Potential Claudin-4 PET Imaging
Pharmaceuticals 10(4), 99 - (2017) [10.3390/ph10040099]
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Journal Article
Motor impairment and compensation in a hemiparkinsonian rat model: correlation between dopamine depletion severity, cerebral metabolism and gait patterns
EJNMMI Research 7(1), 68 (2017) [10.1186/s13550-017-0317-9]
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Journal Article
A Practical Method for the Preparation of 18F-Labeled Aromatic Amino Acids from Nucleophilic [18F]Fluoride and Stannyl Precursors for Electrophilic Radiohalogenation
Molecules 22(12), 2231 - (2017) [10.3390/molecules22122231]
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Conference Presentation (Invited)
FET PET Radiomics - Differenzierung von Tumorprogression und Pseudoprogression beim Glioblastom basierend auf Texturmerkmalen
Gemeinsame Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Nuklearmedizin 2017, DresdenDresden, Germany, 26 Apr 2017 - 29 Apr 2017
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Conference Presentation (Invited)
The relationship of CSF biomarker of tau to in vivo tau pathology is mediated by amyloid levels in AD patients
Neuroscience Day, University of CologneCologne, University of Cologne, Germany, 17 Mar 2017 - 17 Mar 2017
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Journal Article
PSA-Stratified Performance of $^{18}$F- and $^{68}$Ga-PSMA PET in Patients with Biochemical Recurrence of Prostate Cancer
Journal of nuclear medicine 58(6), 947 - 952 (2017) [10.2967/jnumed.116.185538]
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Contribution to a book
Imaging in Neurology Research III: Neurodegenerative Diseases
Small Animal Imaging / Kiessling, Fabian (Editor) ; Cham : Springer International Publishing, 2017, Chapter 30 ; ISBN: 978-3-319-42200-8 ; doi:10.1007/978-3-319-42202-2
Cham : Springer International Publishing 761-772 (2017) [10.1007/978-3-319-42202-2_30]
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Poster (Other)
New approaches to cyclotron production of medical radionuclides
The 22nd International Symposium on Radiopharmaceutical Sciences, iSRS 2017, DresdenDresden, Germany, 14 May 2017 - 19 May 2017
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Conference Presentation (Other)
A novel method for production of high purity $^{73}$Se and its use in a radiosynthesis of $^{73}$Se selenomethionine
The 22nd International Symposium on Radiopharmaceutical Sciences, iSRS 2017, DresdenDresden, Germany, 14 May 2017 - 19 May 2017
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Contribution to a conference proceedings
A practical two-step synthesis of 5-[18F]fluoro-L-tryptophan via alcohol-enhanced Cu-mediated radiofluorination
22nd International Symposium on Radiopharmaceutical Sciences 2017, DredenDreden, Germany, 14 May 2017 - 19 May 2017
New York, NY [u.a.] : Wiley (2017)
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Contribution to a conference proceedings
Synthesis and initial biological evaluation of 7-[18F]fluorotryptophan (7[18F]FTrp)
22nd International Symposium on Radiopharmaceutical Sciences 2017, DresdenDresden, Germany, 14 May 2017 - 19 May 2017
New York, NY [u.a.] : Wiley (2017)
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Contribution to a conference proceedings
Optimization of copper-mediated radiofluorination of arylstannanes
22nd International Symposium on Radiopharmaceutical Sciences 2017, DresdenDresden, Germany, 14 May 2017 - 19 May 2017
New York, NY [u.a.] : Wiley (2017)
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Contribution to a conference proceedings
A novel CDTA-based bifunctional chelator for the preparation of 52g/55MnII-labeled bimodal PET/MR tracers targeting PSMA
22nd International Symposium on Radiopharmaceutical Sciences 2017, DresdenDresden, Germany, 14 May 2017 - 19 May 2017
New York, NY [u.a.] : Wiley (2017)
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Contribution to a conference proceedings
Radiolabelling of dendrimeric ligand structures based on CDTA with [52gMn] – a novel approach towards bimodal PET/MR contrast agents with high relaxivity
22nd International Symposium on Radiopharmaceutical Sciences 2017, DresdenDresden, Germany, 14 May 2017 - 19 May 2017
New York, NY [u.a.] : Wiley (2017)
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Contribution to a conference proceedings
Efficient preparation of 2-[18F]fluorophenylalanine via Cu-mediated radiofluorination
22nd International Symposium on Radiopharmaceutical Sciences 2017, DresdenDresden, Germany, 14 May 2017 - 19 May 2017
New York, NY [u.a.] : Wiley (2017)
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Journal Article
Synthesis and Pharmacological Evaluation of Identified and Putative Metabolites of the A 1 Adenosine Receptor Antagonist 8-Cyclopentyl-3-(3-fluoropropyl)-1-propylxanthine (CPFPX)
ChemMedChem 12(10), 770 - 784 (2017) [10.1002/cmdc.201600592]
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Journal Article
Novel CDTA-based, Bifunctional Chelators for Stable and Inert Mn II Complexation: Synthesis and Physicochemical Characterization
Inorganic chemistry 56(14), 7746 - 7760 (2017) [10.1021/acs.inorgchem.7b00460]
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Journal Article
Imaging of amino acid transport in brain tumours: Positron emission tomography with O-(2-[ 18 F]fluoroethyl)- L -tyrosine (FET)
Methods 130, 124-134 (2017) [10.1016/j.ymeth.2017.05.019]
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Journal Article
Radioiodinated indomethacin amide for molecular imaging of cyclooxygenase-2 expressing tumorsinm-5
OncoTarget 8(11), 18059-18069 (2017) [10.18632/oncotarget.15437]
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Journal Article
Alcohol-Enhanced Cu-Mediated Radiofluorination
Chemistry - a European journal 23(14), 3251 - 3256 (2017) [10.1002/chem.201604633]
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Conference Presentation (Invited)
The production of PET tracers for the diagnosis of oncological and neurological diseases
The First Palestinian International Conference On Peaceful Usage of Atomic Energy, Palestine Technical University in TulkarmPalestine Technical University in Tulkarm, Palestine, 19 Feb 2017 - 20 Feb 2017
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Journal Article
White matter lesions and the cholinergic deficit in aging and mild cognitive impairment
Neurobiology of aging 53, 27 - 35 (2017) [10.1016/j.neurobiolaging.2017.01.012]
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Conference Presentation (Invited)
Tau Tracers: Was können sie? Wann sind sie einsetzbar?
Tagung der österr. Gesellschaft für Nukleramedizin und molekulare Bildgebung (OGNMB), Zell am SeeZell am See, Austria, 18 Jan 2017 - 20 Jan 2017
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Journal Article
Novel ion exchange chromatography method for nca arsenic separation
Applied radiation and isotopes 122, 111 - 115 (2017) [10.1016/j.apradiso.2017.01.008]
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Journal Article
Radiation injury vs. recurrent brain metastasis: combining textural feature radiomics analysis and standard parameters may increase $^{18}$F-FET PET accuracy without dynamic scans
European radiology 27(7), 2916–2927 (2017) [10.1007/s00330-016-4638-2]
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Journal Article
In vivo Patterns of Tau Pathology, Amyloid-β Burden, and Neuronal Dysfunction in Clinical Variants of Alzheimer’s Disease
Journal of Alzheimer's disease 55(2), 465 - 471 (2017) [10.3233/JAD-160316]
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Conference Presentation (Invited)
Radiotracers for diagnostic applications with PET
7th "Georgian – German School and Workshop in Basic Science“, TbilisiTbilisi, Georgia, 28 Aug 2016 - 2 Sep 2016
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Conference Presentation (Invited)
Neue Trends in der 18F-Markierungschemie
Vortrag am Institut für Kernchemie an der Johannes Gutenberg-Universität Mainz, MainzMainz, Germany, 9 May 2016 - 9 May 2016
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Conference Presentation (Invited)
Applications of FASTlab Developer
GE Radiopharmacy and Cyclotron User Forum EANM 2016, BarcelonaBarcelona, Spain, 13 Oct 2016 - 14 Oct 2016
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Conference Presentation (Invited)
Development of Tracers and Theranostics: Radiochemistry
DGN-Summer School 2016, BerlinBerlin, Germany, 25 Aug 2016 - 27 Aug 2016
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Conference Presentation (Invited)
Recent Trends and developments in 18F - radiochemistry
32nd International Austrian Winter Symposium, Zell am SeeZell am See, Austria, 20 Jan 2016 - 23 Jan 2016
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Journal Article
Impact of tau and amyloid burden on glucose metabolism in Alzheimer's disease.
Annals of Clinical and Translational Neurology 3(12), 934 - 939 (2016) [10.1002/acn3.339]
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Journal Article
Prostate-Specific Membrane Antigen-Targeted Radiohalogenated PET and Therapeutic Agents for Prostate Cancer
Journal of nuclear medicine 57(Supplement_3), 90S-96S (2016) [10.2967/jnumed.115.170175]
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Journal Article
The Functional Networks of Prepulse Inhibition: Neuronal Connectivity Analysis Based on FDG-PET in Awake and Unrestrained Rats
Frontiers in behavioral neuroscience 10, 148 (2016) [10.3389/fnbeh.2016.00148]
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Journal Article
Seyferth-Gilbert Homologation as a Route to 18 F-Labeled Building Blocks: Preparation of Radiofluorinated Phenylacetylenes and Their Application in PET Chemistry
European journal of organic chemistry 2016(3), 430 - 433 (2016) [10.1002/ejoc.201501377]
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Journal Article
Automated synthesis of 4-[$^{18}$F]fluoroanisole, [$^{18}$F]DAA1106 and 4-[$^{18}$F]FPhe using Cu-mediated radiofluorination under “minimalist” conditions
Applied radiation and isotopes 115, 133 - 137 (2016) [10.1016/j.apradiso.2016.04.030]
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Journal Article
The Neural Cell Adhesion Molecule-Derived (NCAM)-Peptide FG Loop (FGL) Mobilizes Endogenous Neural Stem Cells and Promotes Endogenous Regenerative Capacity after Stroke
Journal of neuroImmune pharmacology 11(4), 708 - 720 (2016) [10.1007/s11481-016-9694-5]
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Conference Presentation (Plenary/Keynote)
Production of medically useful bromine isotopes via alpha-induced nuclear reactions
International Conference on Nuclear Data for Science and Technology, ND2016, BrugesBruges, Belgium, 11 Sep 2016 - 16 Sep 2016
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Conference Presentation (Plenary/Keynote)
New irradiation Facilities for Development of Production Methods of Medical Radionuclides at Various Cyclotrons at Forschungszentrum Jülich
International Workshop on Targetry and Target Chemistry, Santa FeSanta Fe, USA, 29 Aug 2016 - 1 Sep 2016
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Conference Presentation (Plenary/Keynote)
Preparation of n.c.a. 6-[18F]fluoro-L-tryptophan using copper-mediated radiofluorination
Ninth International Conference on Nuclear and Radiochemistry – NRC9, HelsinkiHelsinki, Finnland, 28 Aug 2016 - 2 Sep 2016
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Poster (Plenary/Keynote)
A novel CDTA-based bifunctional chelator for 52g/55Mn(II)-labeled bimodal PET/MR tracers
Being Smart In Coordination Chemistry: Medical Applications, OrleansOrleans, France, 26 Sep 2016 - 28 Sep 2016
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Poster (Plenary/Keynote)
NOTA- and DOTA-coated gold nanoparticles for bimodal PET-MR molecular imaging
Being Smart In Coordination Chemistry: Medical Applications, OrleansOrleans, France, 26 Sep 2016 - 28 Sep 2016
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Journal Article
Preparation of No-Carrier-Added 6-[$^{18}$ F]Fluoro- l -tryptophan via Cu-Mediated Radiofluorination
European journal of organic chemistry 2016(27), 4621 - 4628 (2016) [10.1002/ejoc.201600705]
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Journal Article
Uses of alpha particles, especially in nuclear reaction studies and medical radionuclide production
Radiochimica acta 104(9), 601–624 (2016) [10.1515/ract-2015-2566]
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Journal Article
Transcranial direct current stimulation accelerates recovery of function, induces neurogenesis and recruits oligodendrocyte precursors in a rat model of stroke
Experimental neurology 279, 127 - 136 (2016) [10.1016/j.expneurol.2016.02.018]
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Journal Article
Glucose consumption of inflammatory cells masks metabolic deficits in the brain
NeuroImage 128, 54 - 62 (2016) [10.1016/j.neuroimage.2015.12.044]
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Poster (Plenary/Keynote)
Authentically radiolabelled Mn(II) complexes as bimodal PET/MR tracers
21st International Symposium on Radiopharmaceutical Sciences, ISRS 2015, ColumbiaColumbia, USA, 26 May 2015 - 31 May 2015
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