Publications 2025
Journal Article
Mapping the interaction surface between CaVβ and actin and its role in calcium channel clearance
Nature Communications 16(1), 4352 (2025) [10.1038/s41467-025-59548-x]
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Journal Article
Identification, validation, and characterization of approved and investigational drugs interfering with the SARS ‐ CoV ‐2 endoribonuclease Nsp15
Protein science 34(6), e70156 (2025) [10.1002/pro.70156]
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Journal Article
Tracing the aggregation pathway of the scaffold protein DISC1: Structural implications for chronic mental illnesses
Journal of structural biology: X 11, 100128 - (2025) [10.1016/j.yjsbx.2025.100128]
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Journal Article
A peptide mimetic therapeutic strategy targeting dysfunction of the scaffold protein DISC-1 in psychiatric disorders
European journal of pharmaceutical sciences 211, 107148 - (2025) [10.1016/j.ejps.2025.107148]
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Patent
Biomarker für die Diagnose von Schlafstörungen
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Journal Article
Identification of non-charged 7.44 analogs interacting with the NHR2 domain of RUNX1-ETO with improved antiproliferative effect in RUNX-ETO positive cells
Scientific reports 15(1), 17720 (2025) [10.1038/s41598-025-02422-z]
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Journal Article
Characterization of a C-methyltransferase from Streptomyces griseoviridis – crystal structure, mechanism, and substrate scope
Chemical science 16(10), 4519 - 4527 (2025) [10.1039/D4SC07300B]
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Journal Article
Loss of Bmal1 impairs the glutamatergic light input to the SCN in mice
Frontiers in cellular neuroscience 19, 1538985 (2025) [10.3389/fncel.2025.1538985]
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Journal Article
Oral PRI-002 treatment in patients with MCI or mild AD: a randomized, double-blind phase 1b trial
Nature Communications 16(1), 4180 (2025) [10.1038/s41467-025-59295-z]
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Journal Article
Guanidinylation of the cold shock protein YB ‐1: Molecular basis, structural changes and Notch‐3 receptor binding
Protein science 34(7), e70188 (2025) [10.1002/pro.70188]
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Journal Article
Insulin amyloid morphology is encoded in H-bonds and electrostatics interactions ruling protein phase separation
Journal of colloid and interface science 683, 1175 - 1187 (2025) [10.1016/j.jcis.2024.12.058]
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Journal Article
Isoleucine Side Chains as Reporters of Conformational Freedom in Protein Folding Studied by DNP-Enhanced NMR
Journal of the American Chemical Society 147(18), 15867 - 15879 (2025) [10.1021/jacs.5c04159]
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Journal Article
Elevated α‐Synuclein Aggregate Levels in the Urine of Patients with Isolated REM Sleep Behavior Disorder and Parkinson's Disease
Annals of neurology 98(1), 147 - 151 (2025) [10.1002/ana.27250]
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Journal Article
Asymmetric synthesis of C–N axially chiral carbazoles via axial-to-axial chirality transfer
Organic & biomolecular chemistry 23(20), 4888 - 4892 (2025) [10.1039/D5OB00587F]
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Journal Article
Novel dietary herbal preparations with inhibitory activities against multiple SARS-CoV-2 targets: A multidisciplinary investigation into antiviral activities
Food chemistry advances 7, 100969 - (2025) [10.1016/j.focha.2025.100969]
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Journal Article
Lecanemab Binds to Transgenic Mouse Model‐Derived Amyloid‐β Fibril Structures Resembling Alzheimer's Disease Type I, Type II and Arctic Folds
Neuropathology & applied neurobiology 51(3), e70022 (2025) [10.1111/nan.70022]
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Journal Article
Innovative strategies for modeling peptide–protein interactions and rational peptide drug design
Current opinion in structural biology 93, 103083 - (2025) [10.1016/j.sbi.2025.103083]
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Patent
Verwendung von D-enantiomeren Peptiden für die Therapie von neuropathischem Schmerz
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