Publications 2025

Journal Article Castilla, F.FZJ* ; Lugo, V.FZJ* ; Miranda-Laferte, E.FZJ* ; Jordan, N.FZJ* ; Huesgen, P. F. ; Santiago-Schübel, B. (Corresponding author)FZJ* ; Alfonso-Prieto, M. (Corresponding author)FZJ* ; Hidalgo, P. (Corresponding author)FZJ*
Mapping the interaction surface between CaVβ and actin and its role in calcium channel clearance
Nature Communications 16(1), 4352 (2025) [10.1038/s41467-025-59548-x]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Chatziefthymiou, S. D. ; Kuzikov, M. ; Afandi, S. ; Kovacs, G. ; Srivastava, S. ; Zaliani, A. ; Gruzinov, A. ; Pompidor, G. ; Lunelli, M. ; Ahmed, G. R. ; Labahn, J.FZJ* ; Hakanpää, J. (Corresponding author) ; Windshügel, B. (Corresponding author) ; Kolbe, M. (Corresponding author)
Identification, validation, and characterization of approved and investigational drugs interfering with the SARS ‐ CoV ‐2 endoribonuclease Nsp15
Protein science 34(6), e70156 (2025) [10.1002/pro.70156]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Cukkemane, A. (Corresponding author)FZJ* ; Becker, N. ; Kupreichyk, T. ; Heise, H.FZJ* ; Willbold, D. (Corresponding author)FZJ* ; Weiergräber, O. H. (Corresponding author)FZJ*
Tracing the aggregation pathway of the scaffold protein DISC1: Structural implications for chronic mental illnesses
Journal of structural biology: X 11, 100128 - (2025) [10.1016/j.yjsbx.2025.100128]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Cukkemane, A. (Corresponding author)FZJ* ; Dingley, A. J.FZJ* ; Mohrlüder, J.FZJ* ; Santiago-Schübel, B.FZJ* ; Weiergräber, O. H. (Corresponding author)FZJ* ; Willbold, D. (Corresponding author)FZJ*
A peptide mimetic therapeutic strategy targeting dysfunction of the scaffold protein DISC-1 in psychiatric disorders
European journal of pharmaceutical sciences 211, 107148 - (2025) [10.1016/j.ejps.2025.107148]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Patent Cukkemane, A. A.FZJ* ; Elmenhorst, D.FZJ* ; Elmenhorst, E.-M.Extern*
Biomarker für die Diagnose von Schlafstörungen
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Journal Article Gopalswamy, M.FZJ* ; Bickel, D. ; Dienstbier, N. ; Tu, J.-W. ; Vogt, M. ; Schott-Verdugo, S.FZJ* ; Bhatia, S. ; Etzkorn, M.FZJ* ; Gohlke, H. (Corresponding author)FZJ*
Identification of non-charged 7.44 analogs interacting with the NHR2 domain of RUNX1-ETO with improved antiproliferative effect in RUNX-ETO positive cells
Scientific reports 15(1), 17720 (2025) [10.1038/s41598-025-02422-z]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Haase, M.FZJ* ; Weiergräber, O. H.FZJ* ; David, B.FZJ* ; Pfirmann, E. L.FZJ* ; Paschold, B.FZJ* ; Gohlke, H. (Corresponding author)FZJ* ; Pietruszka, J. (Corresponding author)
Characterization of a C-methyltransferase from Streptomyces griseoviridis – crystal structure, mechanism, and substrate scope
Chemical science 16(10), 4519 - 4527 (2025) [10.1039/D4SC07300B]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Korkmaz, H. ; Anstötz, M. ; Wellinghof, T. ; Fazari, B. ; Hallenberger, A. ; Bergmann, A. K. ; Niggetiedt, E. ; Güven, F. D. ; Tundo-Lavalle, F. ; Purath, F. F. A. ; Bochinsky, K.FZJ* ; Gremer, L.FZJ* ; Willbold, D.FZJ* ; von Gall, C. (Corresponding author) ; Ali, A. A. H.
Loss of Bmal1 impairs the glutamatergic light input to the SCN in mice
Frontiers in cellular neuroscience 19, 1538985 (2025) [10.3389/fncel.2025.1538985]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Kutzsche, J.FZJ* ; Cosma, N. C. ; Kauselmann, G. ; Fenski, F. ; Bieniek, C. ; Bujnicki, T.FZJ* ; Pils, M.FZJ* ; Bannach, O.FZJ* ; Willbold, D. (Corresponding author)FZJ* ; Peters, O. (Corresponding author)
Oral PRI-002 treatment in patients with MCI or mild AD: a randomized, double-blind phase 1b trial
Nature Communications 16(1), 4180 (2025) [10.1038/s41467-025-59295-z]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Leitz, A. ; Kav, B. ; Liu, X. ; Fatafta, H. ; Jankowski, V. ; Aggeler, B. ; Gao, Y. ; Martin, I. V. ; Vogt, K. ; Kramann, R. ; Ostendorf, T. ; Rauen, T. ; Strodel, B. (Corresponding author)FZJ* ; Raffetseder, U. (Corresponding author)
Guanidinylation of the cold shock protein YB ‐1: Molecular basis, structural changes and Notch‐3 receptor binding
Protein science 34(7), e70188 (2025) [10.1002/pro.70188]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Lenton, S. ; Chaaban, H. ; Khaled, M. ; van de Weert, M. ; Strodel, B. (Corresponding author)FZJ* ; Foderà, V. (Corresponding author)
Insulin amyloid morphology is encoded in H-bonds and electrostatics interactions ruling protein phase separation
Journal of colloid and interface science 683, 1175 - 1187 (2025) [10.1016/j.jcis.2024.12.058]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Levorin, L.FZJ* ; Becker, N. ; Uluca-Yazgi, B.FZJ* ; Gardon, L.FZJ* ; Kraus, M.FZJ* ; Sevenich, M. ; Apostolidis, A. ; Schmitz, K. ; Rüter, N. ; Apanasenko, I.FZJ* ; Willbold, D.FZJ* ; Hoyer, W.FZJ* ; Neudecker, P.FZJ* ; Gremer, L.FZJ* ; Heise, H. (Corresponding author)FZJ*
Isoleucine Side Chains as Reporters of Conformational Freedom in Protein Folding Studied by DNP-Enhanced NMR
Journal of the American Chemical Society 147(18), 15867 - 15879 (2025) [10.1021/jacs.5c04159]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Müller, L.FZJ* ; Özdüzenciler, P.FZJ* ; Schedlich-Teufer, C. ; Seger, A.FZJ* ; Jergas, H. ; Fink, G. R.FZJ* ; Willbold, D.FZJ* ; Sommerauer, M.FZJ* ; Barbe, M. T. ; Tamgüney, G. (Corresponding author)FZJ*
Elevated α‐Synuclein Aggregate Levels in the Urine of Patients with Isolated REM Sleep Behavior Disorder and Parkinson's Disease
Annals of neurology 98(1), 147 - 151 (2025) [10.1002/ana.27250]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Myllek, S. ; Lencer, P.FZJ* ; Klischan, M. K. T. ; Henssen, B.FZJ* ; Neudecker, P.FZJ* ; Breugst, M. ; Pietruszka, J. (Corresponding author)FZJ*
Asymmetric synthesis of C–N axially chiral carbazoles via axial-to-axial chirality transfer
Organic & biomolecular chemistry 23(20), 4888 - 4892 (2025) [10.1039/D5OB00587F]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Olubiyi, O. O. (Corresponding author) ; Attah, F. A. ; Strodel, B.FZJ* ; Eberle, R. J. ; Coronado, M. A. ; Akinseinde, O. ; Onyeaghala, A. A. ; Uzochukwu, I. C. ; Kotila, O. A. ; Dada-Adegbola, H. ; Adepiti, A. O. ; Elujoba, A. A. ; Babalola, C. P. (Corresponding author)
Novel dietary herbal preparations with inhibitory activities against multiple SARS-CoV-2 targets: A multidisciplinary investigation into antiviral activities
Food chemistry advances 7, 100969 - (2025) [10.1016/j.focha.2025.100969]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Peralta Reyes, F. S.FZJ* ; Sommerhage, S.FZJ* ; Willbold, D.FZJ* ; Schröder, G. F. (Corresponding author)FZJ* ; Gremer, L. (Corresponding author)FZJ*
Lecanemab Binds to Transgenic Mouse Model‐Derived Amyloid‐β Fibril Structures Resembling Alzheimer's Disease Type I, Type II and Arctic Folds
Neuropathology & applied neurobiology 51(3), e70022 (2025) [10.1111/nan.70022]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Scharbert, L.FZJ* ; Strodel, B. (Corresponding author)FZJ*
Innovative strategies for modeling peptide–protein interactions and rational peptide drug design
Current opinion in structural biology 93, 103083 - (2025) [10.1016/j.sbi.2025.103083]2025 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Patent Willbold, D.FZJ* ; Kutzsche, J.FZJ* ; Guzman, G.
Verwendung von D-enantiomeren Peptiden für die Therapie von neuropathischem Schmerz
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Last Modified: 24.01.2025