Üffing, A., Weiergräber, O.H., Schwarten, M., Hoffmann, S., and Willbold, D. (2024). GABARAP interacts with EGFR - supporting the unique role of this hAtg8 protein during receptor trafficking. FEBS Lett. (ePub); doi: 10.1002/1873-3468.14997.
Üffing, A., Gold, L., Gensch, T., Weiergräber, O.H., Hoffmann, S., and Willbold, D. (2024). Highlighting the hidden: monitoring the avidity-driven association of a fluorescent GABARAP tandem with microtubules in living cells. Autophagy Rep. 3, 2348899.
Sundermeyer, L., Bosco, G., Gujar, S., Brocker, M., Baumgart, M., Willbold, D., Weiergräber, O.H., Bellinzoni, M., and Bott, M. (2022). Characteristics of the GlnH and GlnX signal transduction proteins controlling PknG-mediated phosphorylation of OdhI and 2-oxoglutarate dehydrogenase activity in Corynebacterium glutamicum. Microbiol. Spectr. 10, e0267722.
Amariei, D.A., Pozhydaieva, N., David, B., Schneider, P., Classen, T., Gohlke, H., Weiergräber, O.H., and Pietruszka, J. (2022). Enzymatic C3-methylation of indoles using methyltransferase PsmD—Crystal structure, catalytic mechanism, and preparative applications. ACS Catal. 12, 14130−14139.
Weiergräber, O.H., Petrović, D., Kislat, A., Pattky, M., Fabig, J., Batra-Safferling, R., Schulte am Esch, J., Hänel, K., Huhn, C., Strodel, B., Homey, B., and Willbold, D. (2022). Structure and dynamics of human chemokine CCL16—implications for biological activity. Biomolecules 12, 1588.
Brown, H., Chung, M., Üffing, A., Batistatou, N., Tsang, T., Doskocil, S., Mao, W., Willbold, D., Bast, R.C. Jr, Lu, Z., Weiergräber, O.H., and Kritzer, J.A. (2022). Structure-based design of stapled peptides that bind GABARAP and inhibit autophagy. J. Am. Chem. Soc. 144, 14687−14697.
Cukkemane A, Becker N, Zielinski M, Frieg B, Lakomek NA, Heise H, Schröder GF, Willbold D, Weiergräber OH. Conformational heterogeneity coupled with β-fibril formation of a scaffold protein involved in chronic mental illnesses. Transl Psychiatry 11, 639 (2021).
Freischem S, Grimm I, López-Pérez A, Willbold D, Klenke B, Vuong C, Dingley AJ, Weiergräber OH. Interaction mode of the novel monobactam AIC499 targeting penicillin binding protein 3 of Gram-negative bacteria. Biomolecules 11, 1057 (2021).
Klionsky DJ, ..., Weiergräber OH, ..., Tong CK. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy 17, 1-382 (2021).
Krichel C, Möckel C, Schillinger O, Huesgen PF, Sticht H, Strodel B, Weiergräber OH, Willbold D, Neudecker P. Solution structure of the autophagy-related protein LC3C reveals a polyproline II motif on a mobile tether with phosphorylation site. Sci Rep 9, 14167 (2019).
Yerabham ASK, Müller-Schiffmann A, Ziehm T, Stadler A, Köber S, Indurkhya X, Marreiros R, Trossbach SV, Bradshaw NJ, Prikulis I, Willbold D, Weiergräber OH, Korth C. Biophysical insights from a single chain camelid antibody directed against the Disrupted-in-Schizophrenia 1 protein. PLoS One 13, e0191162 (2018).
Abdollahzadeh I, Schwarten M, Gensch T, Willbold D, Weiergräber OH. The Atg8 family of proteins—modulating shape and functionality of autophagic membranes. Front Genet
8, 109 (2017).
Weiergräber OH, Schwarten M, Strodel B, Willbold D. Investigating structure and dynamics of Atg8 family proteins. Methods Enzymol 587, 115-142 (2017).
Dick M, Hartmann R, Weiergräber OH, Bisterfeld C, Classen T, Schwarten M, Neudecker P, Willbold D, Pietruszka J. Mechanism-based inhibition of an aldolase at high concentrations of its natural substrate acetaldehyde: structural insights and protective strategies. Chem Sci 7, 4492-4502 (2016).
Dick M, Weiergräber OH, Classen T, Bisterfeld C, Bramski J, Gohlke H, Pietruszka J. Trading off stability against activity in extremophilic aldolases. Sci Rep 6, 17908 (2016).
Michel M, Schwarten M, Decker C, Nagel-Steger L, Willbold D, Weiergräber OH. The mammalian autophagy initiator complex contains 2 HORMA domain proteins. Autophagy 11, 2300-2308 (2015).
Weiergräber OH, Stangler T, Thielmann Y, Mohrlüder J, Wiesehan K, Willbold D. Ligand binding mode of GABAA receptor-associated protein. J Mol Biol 381, 1320-1331 (2008).
