Structural neuroinformatics

Structural Neuroinformatics applies, creates and maintains web-accessible databases of experimental and computational data, together with innovative software tools, essential for understanding the structure/function of proteins expressed in the nervous system in its normal function and in neurological disorders. Structural Neuroinformatics compresses data obtained by traditional structural bioinformatics of proteins expressed in the brain, combined with computational biophysics calculations performed on wild-type proteins together with proteins modified in relation to brain functioning/malfunctioning.

We are currently working in two main topics:

1. Receptors involved in chemoperception:

• Olfactory receptors
• Bitter taste receptors

2. Development of multiscale approaches aimed at gaining insights into the structure function of receptors of neurobiological interest:

Structural System Biology

We are developing a series of tools and approaches aimed at linking molecular detail with a systems biology description of synaptic transmission

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People involved

Dr. Mercedes Alfonso-Prieto

Group leader

• Institute of Neurosciences and Medicine (INM)
• Computational Biomedicine (INM-9)

Building 16.15 /
Room 3001

+49 2461/61-8934

E-Mail

Prof. Alejandro Giorgetti

Associated member

• Computational Biomedicine (INM-9)

Building Ca' Vignal 1 /
Room 1.76

+39(0)45 802 7982

E-Mail

Prof. Dr. Paolo Carloni

Director

• Institute of Neurosciences and Medicine (INM)
• Computational Biomedicine (INM-9)

Building 16.15 /
Room R 3010

+49 2461/61-8941

E-Mail