Project FMMD-MPI
Frequency mixing magnetic detection (FMMD) for Magnetic particle imaging (MPI)
This project is conducted jointly with ETRI, Korea
With the novel magnetic particle imaging (MPI) technique originally developed by B. Gleich and J. Weizenecker (Philips Hamburg), 3D images of the distribution of magnetic nanoparticles (MNP) can be acquired. MNP can be functionalized with antibodies so that they specifically bind to proteins, cells, bacteria or viruses and act as markers. Recently, an MPI imaging system has been built at ETRI which is based on Frequency mixing magnetic detection (FMMD) developed at FZJ. Our aim is to further develop and evaluate this novel magnetic imaging modality regarding its perspectives for medical imaging.
Principal Investigator at FZJ: Dr. Hans-Joachim Krause
Partner: Electronics and Telecommunications Research Institute (ETRI), Daejeon, Korea
Principal Investigator at ETRI: Dr. Hong, Hyobong
Further information: Both partners finance their research individually. Any new IP is owned by the partner who generated it.
Project start: 01.01.2020
Status: active
References:
- S.-M. Choi, J.‑C. Jeong, J. Kim, E.‑G. Lim, C.‑B. Kim, S.‑J. Park, D.‑Y. Song, H.‑J. Krause, H. Hong, I. S. Kweon, A novel three‑dimensional magnetic particle imaging system based on the frequency mixing for the point‑of‑care diagnostics, Scientific Reports 10, 11833 (2020).
- C.-B. Kim, S.-J. Park, J.-C. Jeong, S.-M. Choi, H.-J. Krause, D.-Y. Song, H. Hong, Construction of 3D-rendering imaging of an ischemic rat brain model using the planar FMMD technique, Scientific Reports 9, 19050 (2019).
- C.-B. Kim, E.-G. Lim, S.W. Shin, H.-J. Krause, H. Hong, Magnetic immunoassay platform based on the planar frequency mixing magnetic technique, Biosens. Bioelectron. 83, 293-299 (2016).
- H. Hong, J. Lim, C.-J. Choi, S.-W. Shin, H.-J. Krause, Magnetic particle imaging with a planar frequency mixing magnetic detection scanner, Rev. Sci. Instr. 85, 013705 (2014).