Neuroengineering
Joint lab with the Faculty of Electrical Engineering and IT, RWTH Aachen
The "Neuroelectronic Interfaces" (NEI) Group is a Joint Lab with the Faculty of Electrical Engineering and IT, RWTH Aachen.
The Group is working on Neuroengineering, neuromorphic biohybrids and, within the ERC project BRAIN-ACT, on next generation of interactive biohybrid platforms.
The research group focuses on the design and engineering of electronic materials and micro-devices that can interface with the brain. Neuroelectronic devices have a variety of potential applications, which include the study and treatment of neurodegenerative diseases. As such, the work of the chair has a strong interdisciplinary character, applying engineering principles and design concepts to medicine and biology. An important aspect is the study of biomimetic platforms and coatings that optimize the cell-chip coupling, paving the way towards the implementation of in vitro platforms to investigate and characterize neurodegenerative processes involving synaptic plasticity loss.
Our research topics are focussed on:
ALUMNI:
Antonio Lobosco
Federica Corrado
Ziyu Gao
Csaba Ferro
Claudia Lubrano
Amedeo Ruggiero
Hyunyou Kim
Luca Terenzi
Paola Campione
Cristian Vlad Irimia
Shalini Chaudhuri
RECENT PROJECTS: ERC BRAIN-ACT
RECENT PUBLICATIONS:
Supported lipid bilayers coupled to organic neuromorphic devices modulate short-term plasticity in biomimetic synapses, Lubrano, C., Bruno, U., Ausilio C., Santoro, F., Adv. Mater. (2022) e2110194. doi:10.1002/adma.202110194
A systems theory approach to describe dynamic coupling at the cell–electrode interface, Bruno, U., Mariano, A., Santoro, F., APL Materials 9, 011103 (2021). doi:10.1063/5.0025293
A biohybrid synapse with neurotransmitter-mediated plasticity, Keene, S.T., Lubrano, C., Kazemzadeh, S., Melianas, A., Tuchman, Y., Polino, G., Scognamiglio, P., Cinà, L., Salleo, A., van de Burgt, Y., Santoro, F., Nat. Mater. 19, 969–973 (2020). doi:10.1038/s41563-020-0703-y
Probing the Ultrastructure of Spheroids and Their Uptake of Magnetic Nanoparticles by FIB–SEM, Mollo, V., Scognamiglio, P., Marino, A., Ciofani, G., Santoro, F., Adv. Mater. Technol. 5, 1900687 (2020). doi:10.1002/admt.201900687
Dynamic Manipulation of Cell Membrane Curvature by Light-Driven Reshaping of Azopolymer, De Martino, S., Zhang, W., Klausen, L., Lou, H.-Y, Li, X., Alfonso, F.S., Cavalli, S., Netti, P.A., Santoro, F., Cui, B., Nano Lett. 20 (1), 577–584 (2020). doi:10.1021/acs.nanolett.9b04307