Single-molecule biophysics

Fluorescence spectroscopy of protein properties and their interactions


Our research activities aim to establish a fundamental, physics-based understanding of the function of bio-macromolecular systems. We apply mainly fluorescence based techniques which offer the possibility to measure protein properties and interactions with a high sensitivity and selectivity. The advent of bright and more photo-stable fluorescent dyes and an enormous methodical and technical improvement of high resolution fluorescence spectroscopy and microscopy enabled studies on proteins down to single-molecule level.

Research Topics

Functional Protein Dynamics, Protein Folding and Protein Biosynthesis, Membranes, Interfaces and Compartments, Single Molecule Studies: Technical and Methodical Approaches


Prof. Jörg Fitter


Building 05.2 / Room 4012a

+49 2461/61-2024



Last Modified: 28.07.2022