Articles 2022

Frieg B, Antonschmidt L, Dienemann C, Geraets JA, Najbauer EE, Matthes D, de Groot BL, Andreas LB, Becker S, Griesinger C, Schröder GF.
The 3D structure of lipidic fibrils of α-synuclein.
Nat Commun. 2022 Nov 10;13(1):6810. doi: 10.1038/s41467-022-34552-7. PMID: 36357403; PMCID: PMC9649780.

Frieg B, Geraets JA, Strohäker T, Dienemann C, Mavroeidi P, Jung BC, Kim WS, Lee SJ, Xilouri M, Zweckstetter M, Schröder GF. Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein.
Commun Biol. 2022 Sep 30;5(1):1040. doi: 10.1038/s42003-022-03948-y. PMID: 36180728; PMCID: PMC9525671.

Ibáñez de Opakua A, Geraets JA, Frieg B, Dienemann C, Savastano A, Rankovic M, Cima-Omori MS, Schröder GF, Zweckstetter M. Molecular interactions of FG nucleoporin repeats at high resolution.
Nat Chem. 2022 Nov;14(11):1278-1285. doi: 10.1038/s41557-022-01035-7. Epub 2022 Sep 22. PMID: 36138110; PMCID: PMC9630130.

Antonschmidt L, Matthes D, Dervişoğlu R, Frieg B, Dienemann C, Leonov A, Nimerovsky E, Sant V, Ryazanov S, Giese A, Schröder GF, Becker S, de Groot BL, Griesinger C, Andreas LB.
The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils.
Nat Commun. 2022 Sep 14;13(1):5385. doi: 10.1038/s41467-022-32797-w. PMID: 36104315; PMCID: PMC9474542.

Zinke M, Schröder GF, Lange A.
Major tail proteins of bacteriophages of the order Caudovirales.
J Biol Chem. 2022 Jan;298(1):101472. doi: 10.1016/j.jbc.2021.101472. Epub 2021 Dec 8. PMID: 34890646; PMCID: PMC8718954.