Articles 2025

Review: ESCRTs - a multi-purpose membrane remodeling device encoded in all life forms
Dikla Nachmias, Béla P. Frohn, Carsten Sachse, Itzhak Mizrahi, Natalie Elia
Trends in Microbiology, Cell Press, TIMI 2495

Trigger factor accelerates nascent chain compaction and folding
Katharina Till, Anne-Bart Seinen, Florian Wruck, Vanda Sunderlikova, Carla V. Galmozzi, Alexandros Katranidis, Bernd Bukau, Günter Kramer, and Sander J. Tans
PNAS 2025 Vol. 122 No. 30, DOI 10.1073/pnas.2422678122

The bacterial ESCRT-III PspA rods thin lipid tubules and increase membrane curvature through helix α0 interactions
Esther Hudinaa , Stephan Schott-Verdugo, Benedikt Junglas, Mirka Kutzner, Ilona Ritter, Nadja Hellmann, Dirk Schneider, Holger Gohlke, and Carsten Sachse
PNAS 2025 Vol. 122 No. 32,

High-Density Inverted Micellar Intermediates Promote Membrane Fusion of Cationic Liposomes in Drug Delivery
Rejhana Kolašinac, Erik Strandberg, Laura Maria Schmitt, Sebastian Jaksch, Sabrina Berkamp, Georg Dreissen, Asma Qdemat, Stephan Förster, Carsten Sachse, Anne S. Ulrich, Rudolf Merkel, and Agnes Csiszár
Langmuir 2025 41 (29), 19055-19070DOI: 10.1021/acs.langmuir.5c00659

CryoVIA: An image analysis toolkit for the quantification of membrane structures from cryo-EM micrographs
Philipp Schönnenbeck, Benedikt Junglas, Carsten Sachse
CelPress Open Access

Co-translational ribosome pairing enables native assembly of misfolding-prone subunits
Florian Wruck, Jaro Schmitt , Katharina Till, Kai Fenzl, Matilde Bertolini, Frank Tippmann, Alexandros Katranidis, Bernd Bukau, Günter Kramer & Sander J. Tans
Nature Communications, DOI 10.1038/s41467-025-61500-y