Open Access Publication of the Month – Prof. Dr. Eric von Lieres (IBG-1) et al.
11 February 2025
To encourage us all to broaden our horizons, each month the Central Library selects one open access publication from the JuSER publications portal to be featured in the newsletter of Forschungszentrum Jülich.
In the open access publication of the month, Jesper Frandsen, Jakob Huusom, Krist Gernaey, Jens Abildskov (all from the Technical University of Denmark, DTU), Jan Breuer, Johannes Schmölder, and Eric von Lieres (all from IBG-1) write about an open-source simulation code for chromatographic separation systems in the programming language Julia.
The separation and purification of valuable product molecules is an essential part of biotechnology. Chromatographic processes are often utilized for this purpose as they are highly efficient, but they are also associated with high costs. Therefore, the model-based optimization of such separation processes is instrumental for the economic operation of biotechnological production processes.
The authors present novel algorithms from the class of discontinuous Galerkin methods for the highly precise solution of an entire model family for describing chromatographic separation processes. Depending on the application, the resulting calculations can be up to 100 times faster than with traditional finite volume methods. The high-level language Julia is particularly well- suited for rapid software prototyping and in this study even shows performance benefits over C++. The numerical solver, along with all scripts and data used in the publication, has been released under an open licence on GitHub (https://github.com/cadet).
The open access publication entitled “CADET-Julia: Efficient and versatile, open-source simulator for batch chromatography in Julia” was published in the journal Computers & Chemical Engineering.
JuSER publications portal – CADET-Julia: Efficient and versatile, open-source simulator for batch chromatography in Julia
Forschungszentrum Jülich – Central Library (ZB) – Open Access
Forschungszentrum Jülich – Institute of Bio- and Geosciences (IBG) – Biotechnology (IBG-1)