Publications 2023
Dissertation / PhD Thesis
Dissecting iron and heme regulatory networks and adaptation to heme stress in Corynebacterium glutamicum
286 pp. (2023) = Dissertation, Heinrich-Heine University Düsseldorf, 2023
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Book/Dissertation / PhD Thesis
Dissecting iron and heme regulatory networks and adaptation to heme stress in Corynebacterium glutamicum
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich Reihe Schlüsseltechnologien / Key Technologies 266, IV, 274 (2023) [10.34734/FZJ-2023-01461] = Dissertation, Univ. Düsseldorf, 2022
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Dissertation / PhD Thesis
Multicellular defense against phage infection in Streptomyces-impact of secondary metabolites and mycelial development
245 pp. (2023) = Dissertation, Heinrich-Heine University Düsseldorf, 2023
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Book/Dissertation / PhD Thesis
The complex inositol metabolism of Corynebacterium glutamicum and its application for the production of rare inositols
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich Reihe Schlüsseltechnologien / Key Technologies 269, VI, 161 (2023) [10.34734/FZJ-2023-02247] = Dissertation, Univ. Düsseldorf, 2023
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Dissertation / PhD Thesis
Investigation of protein secretion in microscale cultivation systems with novel tools
149 p. (2023) = Dissertation, RWTH Aachen, 2023
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Dissertation / PhD Thesis
Studies onthe cAMP-responsive regulatory network of Corynebacterium glutamicum
123 pp. (2023) = Dissertation, Heinrich-Heine University Düsseldorf, 2023
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Dissertation / PhD Thesis
Identification of microbial amino acid producers by biosensor-based high-througput screenings and comparative genome analyses
111 pp. (2023) = Dissertation, Heinrich-Heine University Düsseldorf, 2023
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Dissertation / PhD Thesis
Strain-and process engineering for polyketides production with Pseudomonas taiwanensis VLB120 in two-phase cultivations
230 pp. (2023) = Dissertation, Heinrich-Heine University Düsseldorf, 2023
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Book/Dissertation / PhD Thesis
Analysis of the signal transduction cascade tuning the 2-oxoglutarate dehydrogenase activity in Corynebacterium glutamicum
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich Reihe Schlüsseltechnologien / Key Technologies 273, VI, 119 (2023) [10.34734/FZJ-2023-04618] = Dissertation, Univ. Düsseldorf, 2022
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Dissertation / PhD Thesis
Communities of Niche-optimized Strains (CoNoS) - a novel concept for improving biotechnological production
168 pp. (2023) = Dissertation, Heinrich-Heine University Düsseldorf, 2023
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Dissertation / PhD Thesis
Combining multi-step biocatalysis with process intensification - Enzymatic synthesis and downstream processing of chiral amino alcohols from renewables
252 p. (2023) = Dissertation, RWTH Aachen, 2023
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Dissertation / PhD Thesis
Advanced parameter estimation, Bayesian uncertainty quantification, and surrogate modeling for chromatography processes
139 p. (2023) = Dissertation, RWTH Aachen, 2023
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Journal Article
Machine learning in bioprocess development: from promise to practice
Trends in biotechnology 41(6), S0167779922002815 (2023) [10.1016/j.tibtech.2022.10.010]
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Journal Article
Explore or exploit? A model-based screening strategy for PETase secretion by Corynebacterium glutamicum
Biotechnology & bioengineering 120(1), 139 - 153 (2023) [10.1002/bit.28261]
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Journal Article
Three Sides of the Same Coin: Combining Microbial, Enzymatic, and Organometallic Catalysis for Integrated Conversion of Renewable Carbon Sources
Chemie - Ingenieur - Technik 95(4), 485-490 (2023) [10.1002/cite.202200169]
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Journal Article
Effective Production of Selected Dioxolanes by Sequential Bio‐ and Chemocatalysis Enabled by Adapted Solvent Switching
ChemSusChem 16(2), e202201981 (2023) [10.1002/cssc.202201981]
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Journal Article
Pathogen Resistance Depending on Jacalin-Dirigent Chimeric Proteins Is Common among Poaceae but Absent in the Dicot Arabidopsis as Evidenced by Analysis of Homologous Single-Domain Proteins
Plants 12(1), 67 - (2023) [10.3390/plants12010067]
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Journal Article
Enzymatic (2 R ,4 R )‐Pentanediol Synthesis – “Putting a Bottle on the Table”
Chemie - Ingenieur - Technik 95(4), 557-564 (2023) [10.1002/cite.202200178]
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Journal Article
Residue alterations within a conserved hydrophobic pocket influence light, oxygen, voltage photoreceptor dark recovery
Photochemical & photobiological sciences 22, 713-727 (2023) [10.1007/s43630-022-00346-5]
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Journal Article
Characterization and engineering of branched short-chain dicarboxylate metabolism in Pseudomonas reveals resistance to fungal 2-hydroxyparaconate
Metabolic engineering 75, 205 - 216 (2023) [10.1016/j.ymben.2022.12.008]
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Journal Article
EnzymeML: seamless data flow and modeling of enzymatic data
Nature methods 20, 400-402 (2023) [10.1038/s41592-022-01763-1]
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Journal Article
One-shot 13 C15 N-metabolic flux analysis for simultaneous quantification of carbon and nitrogen flux.
Molecular systems biology 19(3), e11099 (2023) [10.15252/msb.202211099]
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Journal Article
From Microbial Succinic Acid Production to Polybutylene Bio‐Succinate Synthesis
Chemie - Ingenieur - Technik 95(4), 587-595 (2023) [10.1002/cite.202200163]
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Journal Article
Systematic analysis of prophage elements in actinobacterial genomes reveals a remarkable phylogenetic diversity
Scientific reports 13(1), 4410 (2023) [10.1038/s41598-023-30829-z]
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Journal Article
Multi-enzyme catalysed processes using purified and whole-cell biocatalysts towards a 1,3,4-substituted tetrahydroisoquinoline
RSC Advances 13(15), 10097 - 10109 (2023) [10.1039/D3RA01210G]
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Journal Article
Bayesian Optimization for an ATP-Regenerating In Vitro Enzyme Cascade
Catalysts 13(3), 468 - (2023) [10.3390/catal13030468]
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Journal Article
A Pseudomonas taiwanensis Malonyl-CoA platform strain for polyketide synthesis
Metabolic engineering 77, 219-230 (2023) [10.1016/j.ymben.2023.04.001]
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Journal Article
Identification and Characterization of Corynaridin, a Novel Linaridin from Corynebacterium lactis
Microbiology spectrum 11(1), e01756-22 (2023) [10.1128/spectrum.01756-22]
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Journal Article
Resolution of Maximum Entropy Method-Derived Posterior Conformational Ensembles of a Flexible System Probed by FRET and Molecular Dynamics Simulations
Journal of chemical theory and computation 19(8), 2389 - 2409 (2023) [10.1021/acs.jctc.2c01090]
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Journal Article
Alternative routes for production of the drug candidate d-chiro-inositol with Corynebacterium glutamicum using endogenous or promiscuous plant enzymes
Metabolic engineering 78, 1 - 10 (2023) [10.1016/j.ymben.2023.04.013]
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Journal Article
Discovery of novel amino acid production traits by evolution of synthetic co-cultures
Microbial cell factories 22(1), 71 (2023) [10.1186/s12934-023-02078-2]
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Journal Article
Enabling oxygen-controlled microfluidic cultures for spatiotemporal microbial single-cell analysis
Frontiers in microbiology 14, 1198170 (2023) [10.3389/fmicb.2023.1198170]
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Journal Article
Engineering a Pseudomonas taiwanensis 4-coumarate platform for production of para-hydroxy aromatics with high yield and specificity
Metabolic engineering 78, 115-127 (2023) [10.1016/j.ymben.2023.05.004]
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Journal Article
New robust subtilisins from halotolerant and halophilic Bacillaceae
Applied microbiology and biotechnology 107(12), 3939 - 3954 (2023) [10.1007/s00253-023-12553-w]
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Journal Article
From frozen cell bank to product assay: high-throughput strain characterisation for autonomous Design-Build-Test-Learn cycles
Microbial cell factories 22(1), 130 (2023) [10.1186/s12934-023-02140-z]
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Journal Article
Experimental k S estimation: A comparison of methods for Corynebacterium glutamicum from lab to microfluidic scale
Biotechnology & bioengineering 120(5), 1288 - 1302 (2023) [10.1002/bit.28345]
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Journal Article
Engineered coumarin accumulation reduces mycotoxin‐induced oxidative stress and disease susceptibility
Plant biotechnology journal 21(12), 2490-2506 (2023) [10.1111/pbi.14144]
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Journal Article
Cellular localization of the hybrid pyruvate/2-oxoglutarate dehydrogenase complex in the actinobacterium Corynebacteriumglutamicum
Microbiology spectrum 11(5), 1-17 (2023) [10.1128/spectrum.02668-23]
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Journal Article
Streptomyces development is involved in the efficient containment of viral infections
Microlife 4, uqad002 (2023) [10.1093/femsml/uqad002]
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Journal Article
Introducing molasses as an alternative feedstock into itaconate production using Ustilago sp
New biotechnology 77, 30 - 39 (2023) [10.1016/j.nbt.2023.06.003]
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Journal Article
Advanced Error Modeling and Bayesian Uncertainty Quantification in Mechanistic Liquid Chromatography Modeling
Journal of chromatography / A 1708, 464329 - (2023) [10.1016/j.chroma.2023.464329]
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Journal Article
Practical sampling of constraint-based models: Optimized thinning boosts CHRR performance
PLoS Computational Biology 19(8), e1011378 - (2023) [10.1371/journal.pcbi.1011378]
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Journal Article
Beyond rational—biosensor-guided isolation of 100 independently evolved bacterial strain variants and comparative analysis of their genomes
BMC biology 21(1), 183 (2023) [10.1186/s12915-023-01688-x]
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Journal Article
Spatial discontinuous Galerkin spectral element method for a family of chromatography models in CADET
Computers & chemical engineering 177, 108340 - (2023) [10.1016/j.compchemeng.2023.108340]
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Journal Article
High-definition simulation of packed-bed liquid chromatography
Computers & chemical engineering 178, 108355 - (2023) [10.1016/j.compchemeng.2023.108355]
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Journal Article
Production of (hydroxy)benzoate-derived polyketides by engineered Pseudomonas with in situ extraction
Bioresource technology 388, 129741 - (2023) [10.1016/j.biortech.2023.129741]
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Journal Article
Development of an itaconic acid production process with Ustilaginaceae on alternative feedstocks
BMC biotechnology 23(1), 34 (2023) [10.1186/s12896-023-00802-9]
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Journal Article
Robotic workflows for automated long-term adaptive laboratory evolution: improving ethanol utilization by Corynebacterium glutamicum
Microbial cell factories 22(1), 175 (2023) [10.1186/s12934-023-02180-5]
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Journal Article
Biochemical characterisation of a novel broad pH spectrum subtilisin from Fictibacillus arsenicus DSM 15822 T
FEBS Open Bio 13(11), 2035 - 2046 (2023) [10.1002/2211-5463.13701]
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Journal Article
Structural and functional characterization of MrpR, the master repressor of the Bacillus subtilis prophage SPβ
Nucleic acids research 51(17), 9452 - 9474 (2023) [10.1093/nar/gkad675]
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Journal Article
Holistic Approach to Process Design and Scale-Up for Itaconic Acid Production from Crude Substrates
Bioengineering 10(6), 723 - (2023) [10.3390/bioengineering10060723]
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Journal Article
Microbial synthesis of the plant natural product precursor p-coumaric acid with Corynebacterium glutamicum
Microbial cell factories 22(1), 209 (2023) [10.1186/s12934-023-02222-y]
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Journal Article
Selective Separation of 4,4’-Methylenedianiline, Isophoronediamine and 2,4-Toluenediamine from Enzymatic Hydrolysis Solutions of Polyurethane
Solvent extraction and ion exchange 41(3), 358 - 373 (2023) [10.1080/07366299.2023.2193229]
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Journal Article
Reliable cell retention of mammalian suspension cells in microfluidic cultivation chambers
Scientific reports 13(1), 3857 (2023) [10.1038/s41598-023-30297-5]
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Master Thesis
Process modelling and analysis of microbial growth dynamics in selective environments
72 p. (2023) = Masterarbeit, RWTH Aachen, 2022
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Master Thesis
Invetigation of factors influencing the enzymatic transamination towards chiral amino alcohols and resulting reaction engineering concepts
123 p. (2023) = Masterarbeit, RWTH Aachen, 2022
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Master Thesis
Improvement of synthetic co-cultures of amino acid-auxotrophic C. glutamicum strains by evolution guided metabolic engineering
68 pp (2023) = Masterarbeit, RWTH Aachen, 2023
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Master Thesis
Advanced Training Algorithms and Uncertainty Quantification for Adsorption Processes in Chromatography
79 p. (2023) = Masterarbeit, RWTH Aachen, 2023
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Master Thesis
Transformation techniques for Corynebacterium glutamicum in an automated laboratory environment
78 p. (2023) = Masterarbeit, RWTH Aachen, 2023
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Master Thesis
Modeling of the pH influence on the adsorption of proteins in cation exchange chromatography
128 p. (2023) = Masterarbeit, RWTH Aachen, 2023
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Bachelor Thesis
Bioprocess development for the production of the bacteriocin garvicin Q in Corynebacterium glutamicum using micro- and laboratory scale automated systems
123 p. (2023) = Bachelorarbeit, RWTH Aachen, 2023
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Master Thesis
Analyzing the Influence of Synthetic and Augmented Data on Segmentation Model
72 p. (2023) = Masterarbeit, Lulea University of Technology, 2023
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Bachelor Thesis
Analysis of a high cell density cultivation protocol for the heterologous production of an amine transaminase in E. coli BL21 (DE3)
89 p. (2023) = Bachelorarbeit, University of Applied Science Bonn-Rhein-sieg, 2023
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Master Thesis
Model-based characterization and adaptive laboratory evolution of Ustilago spec. using glycerol as an alternative carbon source for the production of itaconic acid
93 p. (2023) = Masterarbeit, RWTH Aachen, 2023
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Master Thesis
Reaction engineering for the enzymatic synthesis of metaraminol as an active pharmaceutical ingredient
85 p. (2023) = Masterarbeit, FH Aachen, Campus Jülich, 2023
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Master Thesis
Enzymatic production of (R)-chroman-4-amine hydrochloride using amine transaminases
76 p. (2023) = Masterarbeit, FH Aachen, Campus Jülich, 2023
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Master Thesis
Development of an automated, microcultivation and analytical workflow for screening of peroxygenase producing K. phaffii strains
70 p. (2023) = Masterarbeit, University of Applied Sciences Hamburg, 2023
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Bachelor Thesis
Production of 5,6-decanediol via a synthetic enzymes cascade
105 p. (2023) = Bachelorarbeit, FH Aachen, Campus Jülich, 2023
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Master Thesis
Automated microscopy control for microfluidic time-lapse experimentation utilizing real-time landmark detection and localization
81 p. (2023) = Masterarbeit, FH Aachen, Campus Jülich, 2023
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Master Thesis
Development of a robotic microcultivation workflow for the production of peroxidases in Komagataella phaffii with media optimization
125 p. (2023) = Masterarbeit, RWTH Aachen, 2023
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Master Thesis
Konstruktion und Beurteilung einer Sec-Bibliothek zur heterogenen Expression des antimikrobiellen Paptids Sakacin P in Corynebacterium glutamicum
91 p. (2023) = Masterarbeit, Universität Bonn, 2023
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