Publications 2020
Publications of the IBG-1 from 2020
Master Thesis
Workflow for characterization of catalytically active inclusion bodies of lysine decarboxylase in E. coli with high throughput
84 p. (2020) = Masterarbeit, Hochschule Mannheim, FH, 2020
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Journal Article
Phylogeny and Structure of Fatty Acid Photodecarboxylases and Glucose-Methanol-Choline Oxidoreductases
Catalysts 10(9), 1072 - (2020) [10.3390/catal10091072]
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Master Thesis
Entwicklung eines Workflows zum Aufbau einer MS/MS-Fragmentionen-Datenbank für die metabolische Phänotypisierung mikrobieller Produktionsorganismen
121 p. (2020) = Masterarbeit, RWTH Aachen, 2020
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Journal Article
Improved pEKEx2-derived expression vectors for tightly controlled production of recombinant proteins in Corynebacterium glutamicum
Plasmid 112, 102540 - (2020) [10.1016/j.plasmid.2020.102540]
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Journal Article
Novel plasmid-free Gluconobacter oxydans strains for production of the natural sweetener 5-ketofructose
Microbial cell factories 19(1), 54 (2020) [10.1186/s12934-020-01310-7]
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Journal Article
Efficient Nicotinamide Adenine Dinucleotide Phosphate [NADP(H)] Recycling in Closed‐Loop Continuous Flow Biocatalysis
Advanced synthesis & catalysis 362(14), 2894-2901 (2020) [10.1002/adsc.202000058]
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Journal Article
Compartment Model of Mixing in a Bubble Trap and Its Impact on Chromatographic Separations
Processes 8(7), 780 - (2020) [10.3390/pr8070780]
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Journal Article
An Ustilago maydis chassis for itaconic acid production without by‐products
Microbial biotechnology 13(2), 350 - 362 (2020) [10.1111/1751-7915.13525]
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Bachelor Thesis
Leaderless Translation in Corynebacterium glutamicum
58 pp. (2020) = Bachelorarbeit, FH Aachen, Standort Jülich, 2020
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Contribution to a book
Nutzung mikrobieller und pflanzlicher Diversität in der Biotechnologie
Biodiversität im Meer und an Land: Vom Wert biologischer Vielfalt
Potsdam : Helmholtz-Zentrum Potsdam 50-53 (2020)
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Journal Article
A colourimetric high-throughput screening system for directed evolution of prodigiosin ligase PigC
Chemical communications 56(61), 8631 - 8634 (2020) [10.1039/D0CC02181D]
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Master Thesis
Spatio-temporal analysis of bacterial conjugation in microfluidic cultivation chips at the single-cell level
77 p. (2020) = Masterarbeit, RWTH Aachen, 2020
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Journal Article
Microfluidic cultivation and analysis tools for interaction studies of microbial co-cultures
Current opinion in biotechnology 62, 106 - 115 (2020) [10.1016/j.copbio.2019.09.001]
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Journal Article
Structural features of the glutamate-binding protein from Corynebacterium glutamicum
International journal of biological macromolecules 162, 903 - 912 (2020) [10.1016/j.ijbiomac.2020.06.197]
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Journal Article
Benchtop NMR for online reaction monitoring of the biocatalytic synthesis of aromatic amino alcohols
ChemCatChem 12(4), 1190-1199 (2020) [10.1002/cctc.201901910]
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Journal Article
Stereoselective Reduction of Prochiral Cyclic 1,3-Diketones Using Different Biocatalysts
Catalysis letters 150, 1176-1185 (2020) [10.1007/s10562-019-03015-y]
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Journal Article
Engineering and application of a biosensor with focused ligand specificity
Nature Communications 11(1), 4851 (2020) [10.1038/s41467-020-18400-0]
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Bachelor Thesis
Bioreaction engineering to produce nootkatone from valencene using an immobilized BM3-P450 variant
92 p. (2020) = Bachelorarbeit, FH Aachen, Campus Jülich, 2020
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Journal Article
Enantioselective Ammonium Ylide Mediated One‐Pot Synthesis of Highly Substituted γ ‐Butyrolactones
Advanced synthesis & catalysis 362(12), 2385 - 2396 (2020) [10.1002/adsc.202000039]
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Master Thesis
Immobilization of transaminases for the application in a nano-regulated one-pot cascade
86 p. (2020) = Masterarbeit, FH, Hochschule Offenburg, 2020
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Journal Article
A Fluorescence‐Based Assay System for the Determination of Haloperoxidase‐Activity Using a Two‐Dimensional Calibration Ap‐proach
ChemistryOpen 9(9), 959 - 966 (2020) [10.1002/open.202000184]
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Book/Dissertation / PhD Thesis
Development of a transcriptional biosensor and reengineering of its ligand specificity using fluorescence-activated cell sorting
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich. Reihe Schlüsseltechnologien / Key Technologies 226, VIII, 102 S. (2020) = Heinrich-Heine-Universität Düsseldorf, Diss., 2019
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Journal Article
A tunable l-arabinose-inducible expression plasmid for the acetic acid bacterium Gluconobacter oxydans
Applied microbiology and biotechnology 104(21), 9267 - 9282 (2020) [10.1007/s00253-020-10905-4]
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Master Thesis
Quantitative microbial single-cell analysis under dynamic conditions
130 p. (2020) = Masterarbeit, TU Braunschweig, 2020
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Journal Article
Revisiting the growth modulon of Corynebacterium glutamicum under glucose limited chemostat conditions
Frontiers in Bioengineering and Biotechnology 8, 584614 (2020) [10.3389/fbioe.2020.584614]
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Journal Article
Jahresrückblick Organische Chemie: Naturstoff(total)synthese
Nachrichten aus Chemie und Technik 68, 51-52 (2020)
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Journal Article
Novel Prodiginine Derivatives Demonstrate Bioactivities on Plants, Nematodes, and Fungi
Frontiers in Functional Plant Ecology 11, 579807 (2020) [10.3389/fpls.2020.579807]
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Journal Article
Genome sequence and characterization of five bacteriophagesinfecting Streptomyces coelicolor and Streptomyces venezuelae: Alderaan, Coruscant, Dagobah, Endor1 and Endor2
Viruses 12(10), 1065 - (2020) [10.3390/v12101065]
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Journal Article
Model-based process design of a ternary protein separation using multi-step gradient ion-exchange SMB chromatography
Computers & chemical engineering 138, 106851 (2020) [10.1016/j.compchemeng.2020.106851]
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Bachelor Thesis
Phänotypische Charakterisierung der Phagen-Wirt Interaktion am Beispiel von Streptomyces venezuelae
91 pp. (2020) = Bachelorarbeit, Hochschule Esslingen, 2020
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Journal Article
Screening of a genome-reduced Corynebacterium glutamicum strain library for improved heterologous cutinase secretion
Microbial biotechnology 13(6), 2020-2031 (2020) [10.1111/1751-7915.13660]
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Master Thesis
Development of automated workflows for metabolic phenotyping of a Corynebacterium glutamicum strain library with ultrafast tandem mass spectrometry
74 p. (2020) = Masterarbeit, RWTH Aachen, 2020
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Journal Article
Synthesis of the Thomsen-Friedenreich-antigen (TF-antigen) and binding of Galectin-3 to TF-antigen presenting neo-glycoproteins
Glycoconjugate journal 37(4), 457 - 470 (2020) [10.1007/s10719-020-09926-y]
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Master Thesis
Workflow optimization of split GFP assay for automated screening of cutinase secretion in Corynebacterium glutamicum
97 p. (2020) = Masterarbeit, RWTH Aachen, 2020
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Journal Article
HOPS: high-performance library for (non-)uniform sampling of convex-constrained models
Bioinformatics 37(12), 1776-1777 (2020) [10.1093/bioinformatics/btaa872]
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Journal Article
Catalytically-active inclusion bodies for biotechnology—general concepts, optimization, and application
Applied microbiology and biotechnology 104, 7313-7329 (2020) [10.1007/s00253-020-10760-3]
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Dissertation / PhD Thesis
Advancing automated bioprocess development for industrial platform organisms
129 p. (2020) = Dissertation, RWTH Aachen, 2020
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Journal Article
Parallelized disruption of prokaryotic and eukaryotic cells via miniaturized and automated bead mill
Engineering in life sciences 20(8), 350-356 (2020) [10.1002/elsc.202000002]
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Journal Article
A secretion biosensor for monitoring Sec-dependent protein export in Corynebacterium glutamicum
Microbial cell factories 19(1), 11 (2020) [10.1186/s12934-019-1273-z]
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Master Thesis
Immobilisation of transaminases in temperatur-responsive hydrogels for the control of enzyme cascade reactions
124 p. (2020) = Masterarbeit, RWTH Aachen, 2020
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Bachelor Thesis
Immobilisation of Chromobacterium violaceum transaminases (Cv2025) in temperature-sensitive microgels and hydrogels
97 p. (2020) = Bachelorarbeit, FH, Hochschule Rhein-Waal, 2020
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Journal Article
HrrSA orchestrates a systemic response to heme and determines prioritization of terminal cytochrome oxidase expression
Nucleic acids research 48(12), 6547-6562 (2020) [10.1093/nar/gkaa415]
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Journal Article
Characterization of Context-Dependent Effects on Synthetic Promoters
Frontiers in Bioengineering and Biotechnology 8, 551 (2020) [10.3389/fbioe.2020.00551]
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Dissertation / PhD Thesis
Establishment and application of accelerated bioprocess development for filamentous organisms
168 p. (2020) = Dissertation, RWTH Aachen, 2020
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Journal Article
The iron deficiency response of Corynebacterium glutamicum and a link to thiamine biosynthesis
Applied and environmental microbiology 86, e00065-20 (2020) [10.1128/AEM.00065-20]
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Journal Article
A Straightforward Assay for Screening and Quantification of Biosurfactants in Microbial Culture Supernatants
Frontiers in Bioengineering and Biotechnology 8, 958 (2020) [10.3389/fbioe.2020.00958]
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Journal Article
Adaptive laboratory evolution of Pseudomonas putida and Corynebacterium glutamicum to enhance anthranilate tolerance
Microbiology 166(11), (2020) [10.1099/mic.0.000982]
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Master Thesis
Planalyze: a tool for data analysis and experimental design
87 p. (2020) = Masterarbeit, RWTH Aachen, 2020
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Master Thesis
Metabolic engineering of Corynebacterium glutamicum for the production of a sugar derivative
70 pp. (2020) = Masterarbeit, Heinrich-Heine-Universität Düsseldorf, 2020
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Journal Article
Unraveling 1,4-Butanediol Metabolism in Pseudomonas putida KT2440
Frontiers in microbiology 11, 382 (2020) [10.3389/fmicb.2020.00382]
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Journal Article
ChromaTech: A discontinuous Galerkin spectral element simulator for preparative liquid chromatography
Computers & chemical engineering 141, 107012 - (2020) [10.1016/j.compchemeng.2020.107012]
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Journal Article
Synthesis of the character impact compound raspberry ketone and additional flavoring phenylbutanoids of biotechnological interest with Corynebacterium glutamicum
Microbial cell factories 19(1), 92 (2020) [10.1186/s12934-020-01351-y]
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Journal Article
Engineering intracellular malonyl-CoA availability in microbial hosts and its impact on polyketide and fatty acid synthesis
Applied microbiology and biotechnology 104, 6057–6065 (2020) [10.1007/s00253-020-10643-7]
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Book/Dissertation / PhD Thesis
Engineering of Corynebacterium glutamicum towards increased malonyl-CoA availability for polyketide synthesis
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich. Reihe Schlüsseltechnologien / Key Technologies 223, IX, 117 S. (2020) = Heinrich-Heine-Universität Düsseldorf, Diss., 2020
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Journal Article
Agar plate‐based screening methods for the identification of polyester hydrolysis by Pseudomonas species
Microbial biotechnology 13(1), 274-284 (2020) [10.1111/1751-7915.13418]
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Journal Article
Parallelized microscale fed-batch cultivation in online-monitored microtiter plates: implications of media composition and feed strategies for process design and performance
Journal of industrial microbiology & biotechnology 47, 35-47 (2020) [10.1007/s10295-019-02243-w]
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Master Thesis
Comparative characterization of Lrp-based biosensors derived from different Actinobacterial species for application in Corynebacterium glutamicum ATCC 13032
73 pp. (2020) = Masterarbeit, FH Aachen, 2020
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Journal Article
Synthesis of α-hydroxy ketones and vicinal ( R , R )-diols by Bacillus clausii DSM 8716 T butanediol dehydrogenase
RSC Advances 10(21), 12206 - 12216 (2020) [10.1039/D0RA02066D]
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Journal Article
Synthesis of α-hydroxy ketones and vicinal diols with the Bacillus licheniformis DSM 13T butane-2,3-diol dehydrogenase
Journal of biotechnology 324, 61 - 70 (2020) [10.1016/j.jbiotec.2020.09.016]
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Bachelor Thesis
Post-translational modification of the carboxylate reductase from Nocardia otitidiscaviarum and reaction optimization for the in vitro production of aldehydes
66 p. (2020) = Bachelorarbeit, FH, Hochschule Rhein-Waal, 2020
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Master Thesis
Light regulated enzyme cascade towards the pharmaceutical product tetrahydroisoquinoline
99 p. (2020) = Masterarbeit, Hochschule Offenburg, 2020
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Journal Article
Transglycosylation toward naringenin-7-O-glucoside using an N180H mutant of Coprinopsis cinerea endo-β-N-acetylglucosaminidase
Biochemical and biophysical research communications 530(1), 155 - 159 (2020) [10.1016/j.bbrc.2020.06.128]
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Journal Article
Benzoate Synthesis from Glucose or Glycerol Using Engineered Pseudomonas taiwanensis
Biotechnology journal 15(11), 2000211 - (2020) [10.1002/biot.202000211]
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Dissertation / PhD Thesis
Microbial catalysis of renewable resources into aromatics via the central metabolic precursor phenylalanine
133 pp. (2020) = Dissertation, RWTH Aachen, 2020
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Journal Article
Exceptional Substrate Diversity in Oxygenation Reactions Catalyzed by a Bis(μ‐oxo) Copper Complex
Chemistry - a European journal 26(34), 7556 - 7562 (2020) [10.1002/chem.202000664]
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Bachelor Thesis
Production and stabilization of FRET-based biosensors
54 p. (2020) = Bachelorarbeit, FH Aachen, Campus Jülich, 2020
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Contribution to a book
The Importance of Biotechnology for the Bioeconomy
Bioeconomy for Beginners / Pietzsch, Joachim (Editor) ; Berlin, Heidelberg : Springer Berlin Heidelberg, 2020, Chapter 5 ; ISBN: 978-3-662-60389-5 ; doi:10.1007/978-3-662-60390-1
Berlin, Heidelberg : Springer Berlin Heidelberg 105-128 (2020) [10.1007/978-3-662-60390-1_5]
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Journal Article
Simulation of differential-algebraic equation systems with optimization criteria embedded in Modelica
Computers & chemical engineering 140, 106920 - (2020) [10.1016/j.compchemeng.2020.106920]
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Bachelor Thesis
Erstellung und Untersuchung neuer Corynebacterium glutamicum Stämme zur Sekretion einer heterologen Cutinase
60 p. (2020) = Bachelorarbeit, FH Aachen, Campus Jülich, 2020
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Journal Article
Comprehensive analysis of metabolic sensitivity of 1,4‐butanediol producing Escherichia coli toward substrate and oxygen availability
Biotechnology progress 36(1), e2917 (2020) [10.1002/btpr.2917]
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Bachelor Thesis
Hochzelldichtekultivierung zur Produktion von Amintransaminasen in E. coli BL21 (DE3)
92 p. (2020) = Bachelorarbeit, FH Aachen, Campus Jülich, 2020
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Journal Article
Toward in silico CMC: An industrial collaborative approach to model‐based process development
Biotechnology & bioengineering 117(12), 3986-4000 (2020) [10.1002/bit.27520]
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Bachelor Thesis
Lichtinduzierte Enzyminaktivierung einer Pyruvatdecarboxylase mithilfe von FbFP-und GFB-basierten Photosensitizern
112 p. (2020) = Bachelorarbeit, FH Aachen, Campus Jülich, 2020
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Journal Article
Consolidated bioprocessing of cellulose to itaconic acid by a co-culture of Trichoderma reesei and Ustilago maydis
Biotechnology for biofuels 13(1), 207 (2020) [10.1186/s13068-020-01835-4]
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Journal Article
Pseudomonas as Versatile Aromatics Cell Factory
Biotechnology journal 15(11), 1900569 (2020) [10.1002/biot.201900569]
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Journal Article
A unified design allows fine-tuning of biosensor parameters and application across bacterial species
Metabolic engineering communications 11, e00150 - (2020) [10.1016/j.mec.2020.e00150]
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Journal Article
NADPH biosensor-based identification of an alcohol dehydrogenase variant with improved catalytic properties caused by a single charge reversal at the protein surface
AMB express 10(1), 14 (2020) [10.1186/s13568-020-0946-7]
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Master Thesis
Metabolic characterization of a protease producing Bacillus subtilis strain under pH inhomogeneity in a scale-down bioreactor system
89 p. (2020) = Masterarbeit, RWTH Aachen, 2020
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Journal Article
Complementing the intrinsic repertoire of Ustilago maydis for degradation of the pectin backbone polygalacturonic acid
Journal of biotechnology 307, 148 - 163 (2020) [10.1016/j.jbiotec.2019.10.022]
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Master Thesis
Metabolic response characterization of a protease secreting Bacillus subtilis process under scale-down conditions
117 p. (2020) = Masterarbeit, Universität Erlangen-Nürnberg, 2020
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Journal Article
Dynamic environmental control in microfluidic single‐cell cultivations: From concepts to applications
Small 16(16), 1906670 (2020) [10.1002/smll.201906670]
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Journal Article
dMSCC: a microfluidic platform for microbial single-cell cultivation of Corynebacterium glutamicum under dynamic environmental medium conditions
Lab on a chip 20(23), 4442 - 4455 (2020) [10.1039/D0LC00711K]
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Journal Article
Reversible jump MCMC for multi-model inference in metabolic flux analysis
Bioinformatics 36(1), 232 - 240 (2020) [10.1093/bioinformatics/btz500]
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Journal Article
Integration of genetic and process engineering for optimized rhamnolipid production using pseudomonas putida
Frontiers in Bioengineering and Biotechnology 8, 976 (2020) [10.3389/fbioe.2020.00976]
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Bachelor Thesis
Charakterisierung der a-Ketoglutarat abhängigen Dioxygenasen aus Catenulispora acidiphila, Chitinophaga pinensis und der L-Lysindecarboxylase aus Selenomonas ruminatium
83 p. (2020) = Bachelorarbeit, FH Aachen, Campus Jülich, 2020
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Journal Article
Enantioselective Allylation of Indoles: A Surprising Diastereoselectivity
The journal of organic chemistry 85(4), 1894 - 1905 (2020) [10.1021/acs.joc.9b02573]
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Journal Article
Defined Microbial Mixed Culture for Utilization of Polyurethane Monomers
ACS sustainable chemistry & engineering 8(47), 17466 - 17474 (2020) [10.1021/acssuschemeng.0c06019]
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Journal Article
Model-based performance analysis of pleated filters with non-woven layers
Separation and purification technology 250, 117006 - (2020) [10.1016/j.seppur.2020.117006]
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Journal Article
Structural and dynamic insights revealing how lipase binding domain MD1 of Pseudomonas aeruginosa foldase affects lipase activation
Scientific reports 10(1), 3578 (2020) [10.1038/s41598-020-60093-4]
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Journal Article
Experimental and Computational Investigations of the Reactions between α,β‐Unsaturated Lactones and 1,3‐Dienes by Cooperative Lewis Acid/Brønsted Acid Catalysis
Angewandte Chemie / International edition 59(42), 18709 - 18716 (2020) [10.1002/anie.202008365]
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Journal Article
Engineered PQQ-Dependent Alcohol Dehydrogenase for the Oxidation of 5-(Hydroxymethyl)furoic Acid
ACS catalysis 10(14), 7836 - 7842 (2020) [10.1021/acscatal.0c01789]
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Journal Article
Protocols for yTREX /Tn5‐based gene cluster expression in Pseudomonas putida
Microbial biotechnology 13(1), 250-262 (2020) [10.1111/1751-7915.13402]
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Journal Article
Deciphering the Rules Underlying Xenogeneic Silencing and Counter-Silencing of Lsr2-like Proteins Using CgpS of Corynebacterium glutamicum as a Model
mBio 11(1), e02273-19/mbio/11/1/mBio.02273-19.atom (2020) [10.1128/mBio.02273-19]
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Journal Article
Inducible Expression Systems Based on Xenogeneic Silencing and Counter-Silencing and Design of a Metabolic Toggle Switch
ACS synthetic biology 9(8), 2023 - 2038 (2020) [10.1021/acssynbio.0c00111]
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Dissertation / PhD Thesis
Silencing and counter-silencing of the Lsr2-like protein CgpS in Corynebacterium glutamicum
277 pp. (2020) = Dissertation, Heinrich-Heine-Universität Düsseldorf, 2020
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Journal Article
Metabolic specialization in itaconic acid production: a tale of two fungi
Current opinion in biotechnology 62, 153 - 159 (2020) [10.1016/j.copbio.2019.09.014]
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Bachelor Thesis
Funktionelle Analyse von membrangebundenen Dehydrogenasen in Gluconobacter oxydans
58 pp. (2020) = Bachelorarbeit, FH Aachen, Standort Jülich, 2020
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Journal Article
Molecular Basis of Growth Inhibition by Acetate of an Adenylate Cyclase-Deficient Mutant of Corynebacterium glutamicum
Frontiers in microbiology 11, 87 (2020) [10.3389/fmicb.2020.00087]
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Journal Article
Analysis of the local well‐posedness of optimization‐constrained differential equations by local optimality conditions
AIChE journal 66(10), e16548 (2020) [10.1002/aic.16548]
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Journal Article
Regulation of γ-Aminobutyrate (GABA) Utilization in Corynebacterium glutamicum by the PucR-Type Transcriptional Regulator GabR and by Alternative Nitrogen and Carbon Sources
Frontiers in microbiology 11, 544045 (2020) [10.3389/fmicb.2020.544045]
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Dissertation / PhD Thesis
y-Aminobutyrate as carbon and nitrogen source for Corynebacterium glutamicum and regulation of the catabolic genes by GabR
186 pp. (2020) = Dissertation, Heinrich-Heine-Universität Düsseldorf, 2020
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Bachelor Thesis
Untersuchung der Anwendbarkeit überwachter und nicht-überwachter maschineller Lernmethoden auf Datensätzen von Zeitserienmerkmalen
43 p. (2020) = Bachelorarbeit, FH Aachen, Campus Jülich, 2020
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