Bacterial Networks and Interactions


We study the interaction between bacteria and the viruses (phages) infecting them. Our goal is to gain fundamentally new insights into the bacterial immune system and to apply this knowledge for the development of innovative applications in synthetic biology and biotechnology. Furthermore, we are interested in the design and dynamics of complex regulatory networks enabling microorganisms to adapt to ever changing environments and to discriminate between ‘self’ and ‘foreign’. Microbial model hosts used in our laboratory include the biotechnological platform strain Corynebacterium glutamicum and Streptomyces – the source of most of our antibiotics.

Research Topics

Phage-host interaction: We study how phages target key regulatory hubs of the host cell and how bacteria protect themselves against this attack.

Gene regulatory networks: We study the design and architectures of regulatory networks enabling bacteria to respond to environmental stresses and to interact with other microbes.

Evolutionary engineering: We are harnessing the power of evolution for the development of microbial production strains by using synthetic regulatory circuits and transcription factor-based biosensors.

Further links:


Prof. Dr. Julia Frunzke


Building 15.4 / Room 239

+49 2461/61-5430


Bacterial Networks and Interactions Group 2023
Bacterial Networks and Interactions Group 2023


Prof. Dr. Julia FrunzkeHead of Bacterial Networks and InteractionsBuilding 15.21 / Room 4028+49 2461/61-5430
Dr. Eva DavoudiScientific CoordinatorBuilding 15.21 / Room 4031+49 2461/61-84367


Philipp ErnstPostdocBuilding 15.21 / Room 4032+49 2461/61-84368
Dr. Aileen KrügerPostdocBuilding 15.21 / Room 4031+49 2461/61-84367
Tom LuthePostdocBuilding 15.21 / Room 4033+49 2461/61-84369
Dr. Johanna WiechertPostdocBuilding 15.21 / Room 4031+49 2461/61-84367
Larissa KeverPostdocBuilding 15.21 / Room 4033+49 2461/61-84369


Doris Dohmen-OlmaTechnical staffBuilding 15.21 / Room R 4031+49 2461/61-84367
Cornelia GaetgensTechnicianBuilding 15.21 / Room 4033+49 2461/61-5446
Ulrike WeberTechnicianBuilding 15.21 / Room 4033+49 2461/61-84369

PhD students

Biel Badia RoigéPh.D. studentBuilding 15.21 / Room 4032+49 2461/61-84368
Sebastian ErdrichPhD StudentBuilding 15.21 / Room 4032+49 2461/61-84368
Moses KabuuPh.D. studentBuilding 15.21 / Room 4032+49 2461/61-84368
Mirco KeilhammerPh.D. studentBuilding 15.21 / Room 4031+49 2461/61-84367
Bente RackowPh.D. studentBuilding 15.21 / Room 4032+49 2461/61-84368


Sümeyye CelenStudentBuilding 15.21 / Room 4032+49 2461/61-3953


News and Highlights

April 2023

Tom publishes a paper in Current Opinion in Microbiology doi: 10.1016/j.mib.2023.102314

March 2023

Vikas publishes a paper in Scientific Reports doi: 10.1038/s41598-023-30829-z

Larissa successfully defends her PhD – Congratulations!

SFB1535 MibiNet - Successful start with kick-off meeting

January 2023

Tom publishes a paper in microLife, doi:

Aileen successfully defends her PhD - Congratulations!

November 2022

Annual Group Retreat Waimés, BE

October 2022

The SPP 2330 project “Going-viral 2022”, a phage-hunting experiment for school kids starts!

The Annual SPP 2330 Meeting was held in Rösrath

September 2022

Aileen publishes a paper in frontiers in Microbiology, doi: 10.3389/fmicb.2022.997448

Aileen wins a poster prize at BacNet22!

August 2022

Aël and Larissa publish a review in Trends in Microbiology, doi:

June 2022

Sebastian publishes a paper in Viruses, doi:

Johanna receives a poster prize at the ISBA Meeting. Congratulations!



Last Modified: 01.03.2024