Modeling and Simulation

ABOUT

Group heads:

We provide our local colleagues and the scientific community with state-of-the-art models, algorithms and software. Current challenges in strain characterization, selection and optimization as well as process analysis and development are addressed in a strongly data-driven, mathematically rigorous fashion in close collaboration between theory, simulation and experiment.

Prof. Dr. Eric von Lieres
IBG-1

Building 15.7 / Room 205
phone: +49 2461/61-2168
E-mail

RESEARCH TOPICS

Typical research projects involve data analysis, model calibration or training, uncertainty analysis, parameter estimation, and experimental design. Model predictions are applied for testing hypotheses and focusing experimental work.

Modeling and Simulation

Current key topics are:

  • Live cell image analysis

  • 13C metabolic flux analysis

  • Process chain modeling

  • High definition simulation

  • Bayesian statistical inference and optimization

Dr. Katharina Nöh
IBG-1

Building 15.7 / Room 205
phone: +49 2461/61-9294
E-Mail

Modeling and Simulation

Leader

Prof. Dr. Eric von LieresHead of Modeling and SimulationBuilding 15.7 / Room 205+49 2461/61-2168
Dr. Katharina NöhHead of Modeling of Biochemical Networks and Cells Vice head of Modeling and SimulationBuilding 15.7 / Room R 205+49 2461/61-9294

Scientific staff

Dr. Sabahuddin AhmadScientific staffBuilding 15.7 / Room 204+49 2461/61-1959
Martin BeyßScientific staffBuilding 15.7 / Room 206b+49 2461/61-9065
Laura HelleckesScientific staffBuilding 15.4 / Room 257+49 2461/61-3962
Dr. Ronald JäpelScientific staffBuilding 15.7 / Room 204+49 2461/61-1959
Johannes SchmölderScientific staffBuilding 15.7 / Room 204+49 2461/61-1959

Technician

Birgit StuteTechnicianBuilding 15.7 / Room 204+49 2461/61-1959

Phd students

Antonia BergerPh.D. studentBuilding 15.7 / Room 206+49 2461/61-1959
Ignasi BofarullPh.D. studentBuilding 15.7 / Room 205+49 2461/61-2168
Jan BreuerPh.D. studentBuilding 15.7 / Room 205+49 2461/61-2168
Johann Fredrik JadebeckPh.D. studentBuilding 15.7 / Room 206+49 2461/61-2255
Johannes SeiffarthPh.D. studentBuilding 15.7 / Room 206a+49 2461/61-2255
Maximilian SiskaPh.D. studentBuilding 15.4 / Room 257+49 2461/61-3962
Anton StratmannPh.D. studentBuilding 15.7 / Room 206+49 2461/61-2255

Students

Jasmin JuroszekMaster studentBuilding 15.7 / Room 206a+49 2461/61-9068
Daniel KlaussMaster studentBuilding 15.7 / Room 206a+49 2461/61-9066
Bhavana SitaphaleMaster studentBuilding 15.7 / Room 206+49 2461/61-2255
Dorina von OehsenMaster studentBuilding 15.7 / Room 205+49 2461/61-9294
Xiang XuMaster studentBuilding 15.7 / Room 206a+49 2461/61-2168

Research

Many projects require advanced numerical methods and high-performance computing, in particular when Monte Carlo simulations, global optimization or CFD simulations are applied. We develop and maintain dedicated software packages, most of which are published as open source code (see our GitHub page). The following of our tools are most widely used:

  1. CADET for process chain simulation including, but not limited to, fermentation, filtration and chromatography

  2. 13CFLUX2 for intracellular flux quantification based on carbon labeling experiments

  3. OMIX® for biochemical network visualization (now maintained by a spin-off company)

Last Modified: 02.10.2024