Publikationen 2018
Journal Article
Amyloid-β Peptide Interactions with Amphiphilic Surfactants: Electrostatic and Hydrophobic Effects
ACS chemical neuroscience 9(7), 1680 - 1692 (2018) [10.1021/acschemneuro.8b00065]
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Journal Article
Chaetolines A and B, Pyrano[3,2- f ]isoquinoline Alkaloids from Cultivation of Chaetomium sp. in the Presence of Autoclaved Pseudomonas aeruginosa
Journal of natural products 81(11), 2392 - 2398 (2018) [10.1021/acs.jnatprod.8b00373]
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Journal Article
Pathways of amyloid-β aggregation depend on oligomer shape
Journal of the American Chemical Society 140(1), 319–327 (2018) [10.1021/jacs.7b10343]
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Journal Article
Targeting HSP90 dimerization via the C-terminus is effective in imatinib resistant CML and lacks heat shock response
Blood 132(3), 307-320 (2018) [10.1182/blood-2017-10-810986]
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Journal Article
On the Applicability of Force Fields To Study the Aggregation of Amyloidogenic Peptides Using Molecular Dynamics Simulations
Journal of chemical theory and computation 14(11), 6063 - 6075 (2018) [10.1021/acs.jctc.8b00579]
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Journal Article
Structure and interaction of Corynebacterium pseudotuberculosis cold shock protein A with Y-box single-stranded DNA fragment.
EJB 285(2), 372-390 (2018) [10.1111/febs.14350]
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Journal Article
Inhibition of amyloid Aβ aggregation by high pressures or specific D-enantiomeric peptides
Chemical communications 54(26), 3294 - 3297 (2018) [10.1039/C8CC01458B]
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Journal Article
Zika virus NS2B/NS3 proteinase: A new target for an old drug - Suramin a lead compound for NS2B/NS3 proteinase inhibition-
Antiviral research 160, 118 - 125 (2018) [10.1016/j.antiviral.2018.10.019]
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Journal Article
Relevance of N-terminal residues for amyloid-β binding to platelet integrin α IIb β 3 , integrin outside-in signaling and amyloid-β fibril formation
Cellular signalling 50, 121 - 130 (2018) [10.1016/j.cellsig.2018.06.015]
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Journal Article
Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling
The journal of biological chemistry 293(40), 15359 - 15369 (2018) [10.1074/jbc.RA118.002243]
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Journal Article
Aβ oligomer eliminating compounds interfere successfully with pEAβ (3–42) induced motor neurodegenerative phenotype in transgenic mice
Neuropeptides 67, 27-35 (2018) [10.1016/j.npep.2017.11.011]
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Journal Article
Comprehensive characterization of the pyroglutamate Aβ induced motor neurodegenerative phenotype of TBA2.1 mice
Journal of Alzheimer's disease 63(1), 115-130 (2018) [10.3233/JAD-170775]
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Contribution to a conference proceedings
Demonstration of Power Exhaust Control by Impurity Seeding in the Island Divertor at Wendelstein 7-X
27th IAEA Fusion Energy Conference (FEC 2018), AhmedabadAhmedabad, India, 22 Oct 2018 - 27 Oct 2018
(2018)
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Journal Article
Mechanistic Basis of the Fast Dark Recovery of the Short LOV Protein DsLOV from Dinoroseobacter shibae
Biochemistry 57(32), 4833–4847 (2018) [10.1021/acs.biochem.8b00645]
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Contribution to a conference proceedings/Contribution to a book
Unravelling the Di- and Oligomerisation Interfaces of the G-Protein Coupled Bile Acid Receptor TGR5 via Integrative Modelling
NIC Symposium 2018, JülichJülich, Germany, 22 Feb 2018 - 23 Feb 2018
Jülich : John von Neumann Institute for Computing, Publication Series of the John von Neumann Institute for Computing (NIC) NIC Series 49, 25 - 31 (2018)
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Journal Article
Identification of a Conserved Interface of Human Immunodeficiency Virus Type 1 and Feline Immunodeficiency Virus Vifs with Cullin 5
Journal of virology 92(6), e01697-17 (2018) [10.1128/JVI.01697-17]
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Journal Article
Origin of metastable oligomers and their effects on amyloid fibril self-assembly
Chemical science 9(27), 5937 - 5948 (2018) [10.1039/C8SC01479E]
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Contribution to a book
Chapter 10. Isotopically Enriched Systems
Modern methods in solid-state NMR : a practitioner's guide / Hodgkinson, Paul , London : Royal Society of Chemistry, 2018,
London : Royal Society of Chemistry, New developments in NMR No. 15, xvi, 435 Seiten : illustrations (2018)
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Journal Article
Development and validation of an UHPLC-ESI-QTOF-MS method for quantification of the highly hydrophilic amyloid-β oligomer eliminating all- D -enantiomeric peptide RD2 in mouse plasma
Journal of chromatography / B 1073, 123 - 129 (2018) [10.1016/j.jchromb.2017.12.009]
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Journal Article
Advancements of the sFIDA method for oligomer-based diagnostics of neurodegenerative diseases
FEBS letters 592(4), 516 - 534 (2018) [10.1002/1873-3468.12983]
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Journal Article
Loop Motion in Triosephosphate Isomerase Is Not a Simple Open and Shut Case
Journal of the American Chemical Society 140(46), 15889 - 15903 (2018) [10.1021/jacs.8b09378]
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Journal Article
Aβ under stress: the effects of acidosis, Cu 2+ -binding, and oxidation on amyloid β-peptide dimers
Chemical communications 54(56), 7766 - 7769 (2018) [10.1039/C8CC02263A]
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Journal Article
A novel 10-membered macrocyclic lactone from the mangrove-derived endophytic fungus Annulohypoxylon sp.
Tetrahedron letters 59(7), 632 - 636 (2018) [10.1016/j.tetlet.2018.01.001]
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Journal Article
Efficient non-cytotoxic fluorescent staining of halophiles
Scientific reports 8(1), 2549 (2018) [10.1038/s41598-018-20839-7]
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Journal Article
Recognition motif and mechanism of ripening inhibitory peptides in plant hormone receptor ETR1
Scientific reports 8(1), 3890 (2018) [10.1038/s41598-018-21952-3]
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Journal Article
TopScore: Using Deep Neural Networks and Large Diverse Data Sets for Accurate Protein Model Quality Assessment
Journal of chemical theory and computation 14(11), 6117–6126 (2018) [10.1021/acs.jctc.8b00690]
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Contribution to a conference proceedings/Contribution to a book
Thermodiffusion as a probe of protein hydration for streptavidin and the streptavidin-biotin complex
THE IRAGO CONFERENCE 2017: A 360-degree Outlook on Critical Scientific and Technological Challenges for a Sustainable Society, TokyoTokyo, Japan,
Melville, NY : Inst., AIP conference proceedings 1929, 020001 pp. (2018)
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Journal Article
Molecular basis for diversification of yeast prion strain conformation
Proceedings of the National Academy of Sciences of the United States of America 115(10), 2389 - 2394 (2018) [10.1073/pnas.1715483115]
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Journal Article
Elucidating the multi-targeted anti-amyloid activity and enhanced islet amyloid polypeptide binding of β-wrapins
Computers & chemical engineering 116, 322 - 332 (2018) [10.1016/j.compchemeng.2018.02.013]
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Journal Article
Hydrophobic alkyl chains substituted to the 8-position of cyclic nucleotides enhance activation of CNG and HCN channels by an intricate enthalpy - entropy compensation
Scientific reports 8(1), 14960 (2018) [10.1038/s41598-018-33050-5]
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Journal Article
Physiologically-relevant levels of sphingomyelin, but not GM1, induces a β-sheet-rich structure in the amyloid-β(1-42) monomer
Biochimica et biophysica acta / Biomembranes Biomembranes [...] 1860(9), 1709 - 1720 (2018) [10.1016/j.bbamem.2018.03.026]
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Journal Article
Cholesterol Protects the Oxidized Lipid Bilayer from Water Injury: An All-Atom Molecular Dynamics Study
The journal of membrane biology 251(3), 521 - 534 (2018) [10.1007/s00232-018-0028-9]
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Journal Article
On the contributing role of the transmembrane domain for subunit-specific sensitivity of integrin activation
Scientific reports 8(1), 5733 (2018) [10.1038/s41598-018-23778-5]
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Journal Article
The human platelet antigen-1b variant of $\alpha$$_{IIb}$β$_{3}$ allosterically shifts the dynamic conformational equilibrium of this integrin toward the active state
The journal of biological chemistry 293, 4830-4844 (2018) [10.1074/jbc.RA118.002149]
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Journal Article
How accurately do force fields represent protein side chain ensembles?
Proteins 86(9), 935 - 944 (2018) [10.1002/prot.25525]
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Journal Article
Simulation-Guided Design of Cytochrome P450 for Chemo- and Regioselective Macrocyclic Oxidation
Journal of chemical information and modeling 58(4), 848 - 858 (2018) [10.1021/acs.jcim.8b00043]
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Journal Article
N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament
Structure 26(12), 1604-1611.e4 (2018) [10.1016/j.str.2018.08.007]
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Journal Article
Small-angle X-ray scattering study of the kinetics of light-dark transition in a LOV protein
PLoS one 13(7), e0200746 (2018) [10.1371/journal.pone.0200746]
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Journal Article
Adrenergic Agonists Bind to Adrenergic-Receptor-Like Regions of the Mu Opioid Receptor, Enhancing Morphine and Methionine-Enkephalin Binding: A New Approach to "Biased Opioids"?
International journal of molecular sciences 19(1), 272 (2018) [10.3390/ijms19010272]
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Journal Article
A D-enantiomeric peptide interferes with hetero-association of amyloid-β oligomers and prion protein
The journal of biological chemistry 293, jbc.RA118.003116 - (2018) [10.1074/jbc.RA118.003116]
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Journal Article
In Vitro Reconstitution of the Highly Active and Natively Folded Recombinant Human Superoxide Dismutase 1 Holoenzyme
ChemistrySelect 3(26), 7627 - 7632 (2018) [10.1002/slct.201801319]
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Journal Article
Comparison of blood-brain barrier penetration efficiencies between linear and cyclic all- d -enantiomeric peptides developed for the treatment of Alzheimer's disease
European journal of pharmaceutical sciences 114, 93 - 102 (2018) [10.1016/j.ejps.2017.12.005]
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Journal Article
In Vitro Potency and Preclinical Pharmacokinetic Comparison of All-D-Enantiomeric Peptides Developed for the Treatment of Alzheimer’s Disease
Journal of Alzheimer's disease 64(3), 859 - 873 (2018) [10.3233/JAD-180165]
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Journal Article
Proline Restricts Loop I Conformation of the High Affinity WW Domain from Human Nedd4-1 to a Ligand Binding-Competent Type I β-Turn
The journal of physical chemistry <Washington, DC> / B 122(15), 4219 - 4230 (2018) [10.1021/acs.jpcb.7b11637]
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Journal Article
Conformational Sampling of the Intrinsically Disordered C-Terminal Tail of DERA Is Important for Enzyme Catalysis
ACS catalysis 8(5), 3971 - 3984 (2018) [10.1021/acscatal.7b04408]
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Journal Article
Markov models for the elucidation of allosteric regulation
Philosophical transactions of the Royal Society of London / B Biological sciences Series B 373(1749), 20170178 - (2018) [10.1098/rstb.2017.0178]
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Journal Article
Aspergillus fumigatus Infection-Induced Neutrophil Recruitment and Location in the Conducting Airway of Immunocompetent, Neutropenic, and Immunosuppressed Mice
Journal of Immunology Research 2018(ID 5379085), 1 - 12 (2018) [10.1155/2018/5379085]
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Journal Article
Interaction of Ochratoxin A and Its Thermal Degradation Product 2′R-Ochratoxin A with Human Serum Albumin
Toxins 10(7), 256 - (2018) [10.3390/toxins10070256]
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Journal Article
Schistosomiasis: Snail-vector control, molecular modelling and dynamic studies of bioactive N-acetylglycoside saponins from Tetrapleura tetraptera
Computational biology and chemistry 77, 363 - 372 (2018) [10.1016/j.compbiolchem.2018.09.011]
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Journal Article
DNP-Enhanced MAS NMR: A Tool to Snapshot Conformational Ensembles of α -Synuclein in Different States
Biophysical journal 114(7), 1614 - 1623 (2018) [10.1016/j.bpj.2018.02.011]
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Journal Article
Structural insights from lipid-bilayer nanodiscs link α-Synuclein membrane-binding modes to amyloid fibril formation
Communications biology 1(1), 44 (2018) [10.1038/s42003-018-0049-z]
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Journal Article
Substituted l -tryptophan- l -phenyllactic acid conjugates produced by an endophytic fungus Aspergillus aculeatus using an OSMAC approach
RSC Advances 8(14), 7863 - 7872 (2018) [10.1039/C8RA00200B]
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Journal Article
α-Synuclein Aggregation Monitored by Thioflavin T Fluorescence Assay
Bio-protocol 8(14), PMC6066150 (2018) [10.21769/BioProtoc.2941]
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Journal Article
Expression, purification, and preliminary characterization of human presenilin-2
Process biochemistry 64, 63-73 (2018) [10.1016/j.procbio.2017.09.012]
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Journal Article
Data on solubilization, identification, and thermal stability of human Presenilin-2
Data in Brief 17, 626 - 630 (2018) [10.1016/j.dib.2018.01.039]
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Journal Article
Biophysical insights from a single chain camelid antibody directed against the disrupted in schizophrenia 1 protein
PLoS one 13(1), e0191162 - (2018) [10.1371/journal.pone.0191162]
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Journal Article
Stoichiometric Zn 2+ interferes with the self-association of Aβ42: Insights from size distribution analysis
International journal of biological macromolecules 113, 631-639 (2018) [10.1016/j.ijbiomac.2018.02.123]
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Journal Article
The role of hydrophobicity and charge of amyloid-beta oligomer eliminating D-peptides in the interaction with amyloid-beta monomers
ACS chemical neuroscience 9(11), 2679-2688 (2018) [10.1021/acschemneuro.8b00132]
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