Publikationen 2019

Journal Article Abdollahzadeh, I.FZJ* ; Hendriks, J. ; Sanwald, J. L.FZJ* ; Simons, I. M. ; Hoffmann, S.FZJ* ; Weiergräber, O. H.FZJ* ; Willbold, D.FZJ* ; Gensch, T. (Corresponding author)FZJ*
Autophagy-Related Proteins GABARAP and LC3B Label Structures of Similar Size but Different Shape in Super-Resolution Imaging
Molecules 24(9), 1833 - (2019) [10.3390/molecules24091833]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Agerschou, E. D. ; Saridaki, T. ; Flagmeier, P. ; Galvagnion, C. ; Komnig, D. ; Nagpal, A. ; Gasterich, N. ; Heid, L. ; Prasad, V. ; Shaykhalishahi, H. ; Voigt, A. ; Willbold, D.FZJ* ; Dobson, C. M. ; Falkenburger, B. H. (Corresponding author) ; Hoyer, W. (Corresponding author)FZJ* ; Buell, A. K. (Corresponding author)
An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils
eLife 8, e46112 (2019) [10.7554/eLife.46112]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Alvarez, C. E. ; Bovdilova, A. ; Höppner, A. ; Wolff, C.-C. ; Saigo, M. ; Trajtenberg, F. ; Zhang, T. ; Buschiazzo, A. ; Nagel-Steger, L.FZJ* ; Drincovich, M. F. ; Lercher, M. J. ; Maurino, V. G. (Corresponding author)
Molecular adaptations of NADP-malic enzyme for its function in C4 photosynthesis in grasses
Nature plants 5(7), 755 - 765 (2019) [10.1038/s41477-019-0451-7]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Barz, B.FZJ* ; Loschwitz, J.FZJ* ; Strodel, B. (Corresponding author)FZJ*
Large-scale, dynamin-like motions of the human guanylate binding protein 1 revealed by multi-resolution simulations
PLoS Computational Biology 15(10), e1007193 - (2019) [10.1371/journal.pcbi.1007193]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Bickel, D. ; Gohlke, H. (Corresponding author)FZJ*
C-terminal Modulators of Heat Shock Protein of 90 kDa (HSP90): State of Development and Modes of Action
Bioorganic & medicinal chemistry 27(21), 115080 (2019) [10.1016/j.bmc.2019.115080]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Bleffert, F.FZJ* ; Granzin, J.FZJ* ; Gohlke, H.FZJ* ; Batra-Safferling, R. (Corresponding author)FZJ* ; Jaeger, K.-E. (Corresponding author)FZJ* ; Kovacic, F. (Corresponding author)FZJ*
Pseudomonas aeruginosa esterase PA2949, a bacterial homolog of the human membrane esterase ABHD6: expression, purification and crystallization
Acta crystallographica / F Structural biology communications Section F F75(4), 270 - 277 (2019) [10.1107/S2053230X19002152]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Bovdilova, A. ; Alexandre, B. M. ; Höppner, A. ; Matias Luís, I. ; Alvarez, C. E. ; Bickel, D. ; Gohlke, H.FZJ* ; Decker, C.FZJ* ; Nagel-Steger, L.FZJ* ; Alseekh, S. ; Fernie, A. R. ; Drincovich, M. F. ; Abreu, I. A. ; Maurino, V. G. (Corresponding author)
Posttranslational modification of the NADP-malic enzyme involved in C4 photosynthesis fine-tunes the enzymatic activity during the day
The plant cell 31(10), 2525-2539 (2019) [10.1105/tpc.19.00406]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Dimura, M. ; Ottavio Peulen, T. ; Sanabria, H. ; Rodnin, D. ; Hemmen, K. ; Seidel, C. A. M. (Corresponding author)Extern* ; Gohlke, H. (Corresponding author)FZJ*
Automated and Optimally FRET-Assisted Structural Modeling
Biophysical journal 116(3, Suppl 1) 333a - (2019) [10.1016/j.bpj.2018.11.1815]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Dittrich, J. ; Schmidt, D. ; Pfleger, C. ; Gohlke, H. (Corresponding author)FZJ*
Converging a Knowledge-Based Scoring Function: DrugScore2018
Journal of chemical information and modeling 59(1), 509–521 (2019) [10.1021/acs.jcim.8b00582]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Dreyer, I. (Corresponding author) ; Spitz, O. ; Kanonenberg, K. ; Montag, K. ; Handrich, M. ; Ahmad, S. ; Schott-Verdugo, S. ; Navarro-Retamal, C. ; Rubio-Meléndez, M. E. ; Gomez-Porras, J. L. ; Riedelsberger, J. ; Molina-Montenegro, M. A. ; Succurro, A. ; Zuccaro, A. ; Gould, S. B. ; Bauer, P. ; Schmitt, L. ; Gohlke, H.FZJ*
Nutrient exchange in arbuscular mycorrhizal symbiosis from a thermodynamic point of view
The new phytologist 222(2), 1043-1053 (2019) [10.1111/nph.15646]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Elfgen, A.FZJ* ; Hupert, M.FZJ* ; Bochinsky, K.FZJ* ; Tusche, M.FZJ* ; González de San Román Martin, E. ; Gering, I.FZJ* ; Sacchi, S. ; Pollegioni, L. ; Huesgen, P. F.FZJ* ; Hartmann, R.FZJ* ; Santiago-Schübel, B.FZJ* ; Kutzsche, J. (Corresponding author)FZJ* ; Willbold, D. (Corresponding author)FZJ*
Metabolic resistance of the D-peptide RD2 developed for direct elimination of amyloid-β oligomers
Scientific reports 9(1), 5715 (2019) [10.1038/s41598-019-41993-6]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Falke, M. ; Victor, J. ; Wördehoff, M. M. ; Peduzzo, A. ; Zhang, T.FZJ* ; Schröder, G. F.FZJ* ; Buell, A. K. ; Hoyer, W.FZJ* ; Etzkorn, M. (Corresponding author)FZJ*
α-Synuclein-derived lipoparticles in the study of α-Synuclein amyloid fibril formation
Chemistry and physics of lipids 220, 57 - 65 (2019) [10.1016/j.chemphyslip.2019.02.009]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Gordeliy, V. (Corresponding author)FZJ* ; Bratanov, D.FZJ* ; Kovalev, K. ; Machtens, J.-P.FZJ* ; Astashkin, R. ; Chizhov, I. ; Soloviov, D. ; Volkov, D.FZJ* ; Polovinkin, V. ; Zabelskii, D.FZJ* ; Mager, T. ; Gushchin, I. ; Rokitskaya, T. ; Antonenko, Y. ; Alekseev, A. ; Shevchenko, V. ; Yutin, N. ; Rosselli, R. ; Baeken, C.FZJ* ; Borshchevskiy, V.FZJ* ; Bourenkov, G. ; Popov, A. ; Balandin, T.FZJ* ; Büldt, G. ; Manstein, D. J. ; Rodriguez-Valera, F. ; Fahlke, C.FZJ* ; Bamberg, E. ; Koonin, E.
Unique structure and function of viral rhodopsins
Nature Communications 10(1), 4939 (2019) [10.1038/s41467-019-12718-0]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Haupeltshofer, S. ; Leichsenring, T. ; Berg, S. ; Pedreiturria, X. ; Joachim, S. C. ; Tischoff, I. ; Otte, J.-M. ; Bopp, T. ; Fantini, M. C. ; Esser, C. ; Willbold, D.FZJ* ; Gold, R. ; Faissner, S. ; Kleiter, I. (Corresponding author)
Smad7 in intestinal CD4 + T cells determines autoimmunity in a spontaneous model of multiple sclerosis
Proceedings of the National Academy of Sciences of the United States of America 116(51), 25860 - 25869 (2019) [10.1073/pnas.1905955116]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Kater, L. ; Frieg, B.FZJ* ; Berninghausen, O. ; Gohlke, H. (Corresponding author)FZJ* ; Beckmann, R. (Corresponding author) ; Kedrov, A. (Corresponding author)
Partially inserted nascent chain unzips the lateral gate of the Sec translocon
EMBO reports 20, e48191 (2019) [10.15252/embr.201948191]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Khan, I. ; Gratz, R. ; Denezhkin, P. ; Schott-Verdugo, S. N. ; Angrand, K. ; Genders, L. ; Basgaran, R. M. ; Fink-Straube, C. ; Brumbarova, T. ; Gohlke, H.FZJ* ; Bauer, P. ; Ivanov, R. (Corresponding author)
Calcium-promoted interaction between the C2-domain protein EHB1 and metal transporter IRT1 inhibits Arabidopsis iron acquisition
Plant physiology 180(3), 1564-1581 (2019) [10.1104/pp.19.00163]2019 Files BibTeX | EndNote: XML, Text | RIS

Journal Article Klinker, S. ; Stindt, S. ; Gremer, L.FZJ* ; Bode, J. G. ; Gertzen, C. G. W. ; Gohlke, H.FZJ* ; Weiergräber, O. H.FZJ* ; Hoffmann, S.FZJ* ; Willbold, D. (Corresponding author)FZJ*
Phosphorylated tyrosine 93 of hepatitis C virus nonstructural protein 5A is essential for interaction with host c-Src and efficient viral replication
The journal of biological chemistry 294, 7388-7402 (2019) [10.1074/jbc.RA119.007656]2019 Files BibTeX | EndNote: XML, Text | RIS

Journal Article Koch, A. ; Bonus, M. ; Gohlke, H.FZJ* ; Klöcker, N. (Corresponding author)
Isoform-specific Inhibition of N-methyl-D-aspartate Receptors by Bile Salts
Scientific reports 9(1), 10068 (2019) [10.1038/s41598-019-46496-y]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article König, A.FZJ* ; Schölzel, D.FZJ* ; Uluca, B.FZJ* ; Viennet, T. ; Akbey, Ü.FZJ* ; Heise, H. (Corresponding author)FZJ*
Hyperpolarized MAS NMR of unfolded and misfolded proteins
Solid state nuclear magnetic resonance 98, 1-11 (2019) [10.1016/j.ssnmr.2018.12.003]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Krichel, C. ; Möckel, C.FZJ* ; Schillinger, O. ; Huesgen, P. F.FZJ* ; Sticht, H. ; Strodel, B.FZJ* ; Weiergräber, O. H.FZJ* ; Willbold, D. (Corresponding author)FZJ* ; Neudecker, P. (Corresponding author)FZJ*
Solution structure of the autophagy-related protein LC3C reveals a polyproline II motif on a mobile tether with phosphorylation site
Scientific reports 9(1), 14167 (2019) [10.1038/s41598-019-48155-8]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Krieger, V. ; Hamacher, A. ; Cao, F. ; Stenzel, K. ; Gertzen, C. G. W.FZJ* ; Schäker-Hübner, L. ; Kurz, T. ; Gohlke, H.FZJ* ; Dekker, F. J. ; Kassack, M. U. (Corresponding author) ; Hansen, F. K. (Corresponding author)
Synthesis of peptoid-based class I selective histone deacetylase inhibitors with chemosensitizing properties
Journal of medicinal chemistry 62(24), 11260-11279 (2019) [10.1021/acs.jmedchem.9b01489]2019 Files BibTeX | EndNote: XML, Text | RIS

Journal Article Kukuk, L.FZJ* ; Dingley, A. J.FZJ* ; Granzin, J.FZJ* ; Nagel-Steger, L.FZJ* ; Thiagarajan-Rosenkranz, P. ; Ciupka, D. ; Hänel, K.FZJ* ; Batra-Safferling, R.FZJ* ; Pacheco, V. ; Stoldt, M.FZJ* ; Pfeffer, K. ; Beer-Hammer, S. ; Willbold, D. (Corresponding author)FZJ* ; Koenig, B. W. (Corresponding author)FZJ*
Structure of the SLy1 SAM homodimer reveals a new interface for SAM domain self-association
Scientific reports 9(1), 54 (2019) [10.1038/s41598-018-37185-3]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Legewie, L. ; Loschwitz, J.FZJ* ; Steffens, N. ; Prescher, M. ; Wang, X.FZJ* ; Smits, S. H. J. ; Schmitt, L. ; Strodel, B.FZJ* ; Degrandi, D. (Corresponding author) ; Pfeffer, K. (Corresponding author)
Biochemical and structural characterization of murine GBP7, a guanylate binding protein with an elongated C-terminal tail
Biochemical journal 476(21), 3161 - 3182 (2019) [10.1042/BCJ20190364]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Leypold, T. ; Bonus, M. ; Spiegelhalter, F. ; Schwede, F. ; Schwabe, T. ; Gohlke, H.FZJ* ; Kusch, J. (Corresponding author)
N 6 -modified cAMP derivatives that activate protein kinase A also act as full agonists of murine HCN2 channels
The journal of biological chemistry 294, 17978-17987 (2019) [10.1074/jbc.RA119.010246]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Lin, M. ; Nebral, K. ; Gertzen, C.FZJ* ; Ganmore, I. ; Haas, O. A. ; Bhatia, S. ; Fischer, U. ; Kuhlen, M. ; Gohlke, H.FZJ* ; Izraeli, S. ; Trka, J. ; Hu, J. ; Borkhardt, A. ; Hauer, J. (Corresponding author) ; Auer, F. (Corresponding author)
JAK2 p.G571S in B-cell precursor acute lymphoblastic leukemia: a synergizing germline susceptibility
Leukemia 33, 2331–2335 (2019) [10.1038/s41375-019-0459-z]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Lohmann, S. ; Bernis, M. E. ; Tachu, B. J. ; Ziemski, A.FZJ* ; Grigoletto, J. ; Tamgüney, G. (Corresponding author)FZJ*
Oral and intravenous transmission of α-synuclein fibrils to mice
Acta neuropathologica 138(4), 515 - 533 (2019) [10.1007/s00401-019-02037-5]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Mechsner, B.FZJ* ; Böse, D.FZJ* ; Hogenkamp, F.FZJ* ; Ledermann, N. ; Hartmann, R.FZJ* ; Bochinsky, K.FZJ* ; Frey, W. ; Pietruszka, J. (Corresponding author)FZJ*
Enantioselective total synthesis of altersolanol A and N
Bioorganic & medicinal chemistry 27(13), 2991 - 2997 (2019) [10.1016/j.bmc.2019.04.033]2019 BibTeX | EndNote: XML, Text | RIS

Journal Article Möckel, C.FZJ* ; Kubiak, J. ; Schillinger, O. ; Kühnemuth, R. ; Della Corte, D. ; Schröder, G. F.FZJ* ; Willbold, D.FZJ* ; Strodel, B. (Corresponding author)FZJ* ; Seidel, C. A. M. (Corresponding author)FZJ* ; Neudecker, P. (Corresponding author)FZJ*
Integrated NMR, Fluorescence, and Molecular Dynamics Benchmark Study of Protein Mechanics and Hydrodynamics
The journal of physical chemistry <Washington, DC> / B B, Condensed matter, materials, surfaces, interfaces & biophysical 123(7), 1453 - 1480 (2019) [10.1021/acs.jpcb.8b08903]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Moussa, M. ; Ebrahim, W. ; Bonus, M. ; Gohlke, H.FZJ* ; Mándi, A. ; Kurtán, T. ; Hartmann, R.FZJ* ; Kalscheuer, R. ; Lin, W. ; Liu, Z. (Corresponding author) ; Proksch, P. (Corresponding author)
Co-culture of the fungus Fusarium tricinctum with Streptomyces lividans induces production of cryptic naphthoquinone dimers
RSC Advances 9(3), 1491 - 1500 (2019) [10.1039/C8RA09067J]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Nazarenko, V. V. ; Remeeva, A. ; Yudenko, A. ; Kovalev, K. ; Dubenko, A. ; Goncharov, I. M. ; Kuzmichev, P. ; Rogachev, A. V. ; Buslaev, P. ; Borshchevskiy, V.FZJ* ; Mishin, A. ; Dhoke, G. V. ; Schwaneberg, U. ; Davari, M. D. ; Jaeger, K.-E.FZJ* ; Krauss, U.FZJ* ; Gordeliy, V.FZJ* ; Gushchin, I. (Corresponding author)
A thermostable flavin-based fluorescent protein from Chloroflexus aggregans : a framework for ultra-high resolution structural studies
Photochemical & photobiological sciences 18(7), 1793 - 1805 (2019) [10.1039/C9PP00067D]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Nerius, M. ; Doblhammer, G. ; Tamgüney, G. (Corresponding author)
GI infections are associated with an increased risk of Parkinson’s disease
Gut 69(6), (2019) [10.1136/gutjnl-2019-318822]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Olubiyi, O. (Corresponding author)FZJ* ; Olagunju, M. O.FZJ* ; Strodel, B.FZJ*
Rational Drug Design of Peptide-Based Therapies for Sickle Cell Disease
Molecules 24(24), 4551 - (2019) [10.3390/molecules24244551]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Otte, M. ; Schweinitz, A. ; Lelle, M. ; Thon, S. ; Enke, U. ; Yüksel, S. ; Schmauder, R. ; Bonus, M. ; Gohlke, H.FZJ* ; Benndorf, K. (Corresponding author)
Novel Fluorescent Cyclic Nucleotide Derivatives to Study CNG and HCN Channel Function
Biophysical journal 116(12), 2411-2422 (2019) [10.1016/j.bpj.2019.05.006]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Otten, J.FZJ* ; Tenhaef, N.FZJ* ; Jansen, R. P.FZJ* ; Döbber, J. ; Jungbluth, L.FZJ* ; Noack, S.FZJ* ; Oldiges, M.FZJ* ; Wiechert, W.FZJ* ; Pohl, M. (Corresponding author)FZJ*
A FRET-based biosensor for the quantification of glucose in culture supernatants of mL scale microbial cultivations
Microbial cell factories 18(1), 143 (2019) [10.1186/s12934-019-1193-y]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Owen, M. C. ; Gnutt, D. ; Gao, M. ; Wärmländer, S. K. T. S. ; Jarvet, J. ; Gräslund, A. ; Winter, R. ; Ebbinghaus, S. ; Strodel, B. (Corresponding author)FZJ*
Effects of in vivo conditions on amyloid aggregation
Chemical Society reviews 48(14), 3946 - 3996 (2019) [10.1039/C8CS00034D]2019 Files BibTeX | EndNote: XML, Text | RIS

Journal Article Perez, C. ; Miti, T. ; Hasecke, F.FZJ* ; Meisl, G. ; Hoyer, W.FZJ* ; Muschol, M. ; Ullah, G. (Corresponding author)
Mechanism of Fibril and Soluble Oligomer Formation in Amyloid Beta and Hen Egg White Lysozyme Proteins
The journal of physical chemistry <Washington, DC> / B B, Condensed matter, materials, surfaces, interfaces & biophysical 123(27), 5678 - 5689 (2019) [10.1021/acs.jpcb.9b02338]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Perov, S. ; Lidor, O. ; Salinas, N. ; Golan, N. ; Tayeb- Fligelman, E. ; Deshmukh, M. ; Willbold, D.FZJ* ; Landau, M. (Corresponding author)
Structural Insights into Curli CsgA Cross-β Fibril Architecture Inspire Repurposing of Anti-amyloid Compounds as Anti-biofilm Agents
PLoS pathogens 15(8), e1007978 - (2019) [10.1371/journal.ppat.1007978]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Porta, N. ; Zaschke-Kriesche, J. ; Frieg, B.FZJ* ; Gopalswamy, M.FZJ* ; Zivkovic, A. ; Etzkorn, M.FZJ* ; Stark, H. ; Smits, S. H. J. ; Gohlke, H. (Corresponding author)FZJ*
Small-molecule inhibitors of nisin resistance protein NSR from the human pathogen Streptococcus agalactiae
Bioorganic & medicinal chemistry 27(20), 115079 (2019) [10.1016/j.bmc.2019.115079]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Preising, M. N. ; Görg, B. ; Friedburg, C. ; Qvartskhava, N. ; Budde, B. S. ; Bonus, M. ; Toliat, M. R. ; Pfleger, C. ; Altmüller, J. ; Herebian, D. ; Beyer, M. ; Zöllner, H. J. ; Wittsack, H.-J. ; Schaper, J. ; Klee, D. ; Zechner, U. ; Nürnberg, P. ; Schipper, J. ; Schnitzler, A. ; Gohlke, H.FZJ* ; Lorenz, B. ; Häussinger, D. (Corresponding author) ; Bolz, H. J. (Corresponding author)
Biallelic mutation of human SLC6A6 encoding the taurine transporter TAUT is linked to early retinal degeneration
The FASEB journal 33(10), 11507–11527 (2019) [10.1096/fj.201900914RR]2019 Files BibTeX | EndNote: XML, Text | RIS

Journal Article Raudszus, R. ; Nowotny, R. ; Gertzen, C. G. W.FZJ* ; Schöler, A. ; Krizsan, A. ; Gockel, I. ; Kalwa, H. ; Gohlke, H.FZJ* ; Thieme, R. ; Hansen, F. K. (Corresponding author)
Fluorescent analogs of peptoid-based HDAC inhibitors: Synthesis, biological activity and cellular uptake kinetics
Bioorganic & medicinal chemistry 27(19), 115039 - (2019) [10.1016/j.bmc.2019.07.055]2019 Files BibTeX | EndNote: XML, Text | RIS

Journal Article Reßing, N. ; Marquardt, V. ; Gertzen, C.FZJ* ; Schöler, A. ; Schramm, A. ; Kurz, T. ; Gohlke, H.FZJ* ; Aigner, A. ; Remke, M. ; Hansen, F. K. (Corresponding author)
Design, Synthesis and Biological Evaluation of β-Peptoid-Capped HDAC Inhibitors with Anti-Neuroblastoma and Anti-Glioblastoma Activity
MedChemComm 10(7), 1109-1115 (2019) [10.1039/C8MD00454D]2019 Files BibTeX | EndNote: XML, Text | RIS

Journal Article Röder, C.FZJ* ; Vettore, N. ; Mangels, L. N.FZJ* ; Gremer, L.FZJ* ; Ravelli, R. B. G. ; Willbold, D.FZJ* ; Hoyer, W.FZJ* ; Buell, A. K. (Corresponding author) ; Schröder, G. (Corresponding author)FZJ*
Atomic structure of PI3-kinase SH3 amyloid fibrils by cryo-electron microscopy
Nature Communications 10(1), 3754 (2019) [10.1038/s41467-019-11320-8]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Sachs, J. ; Döhl, K. ; Weber, A. ; Bonus, M. ; Ehlers, F. ; Fleischer, E. ; Klinger, A. ; Gohlke, H.FZJ* ; Pietruszka, J.FZJ* ; Schmitt, L. ; Teusch, N. (Corresponding author)
Novel 3,4-Dihydroisocoumarins Inhibit Human P-gp and BCRP in Multidrug Resistant Tumors and Demonstrate Substrate Inhibition of Yeast Pdr5
Frontiers in pharmacology 10, 400 (2019) [10.3389/fphar.2019.00400]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Sarter, M.FZJ* ; Stadler, A. (Corresponding author)FZJ* ; Niether, D.FZJ* ; Koenig, B. W. ; Zamponi, M.FZJ* ; Wiebke, L. ; Wiegand, S. ; Fitter, J.FZJ*
The Relevance of Conformational Entropy for Protein Ligand Interactions: the Case of Biotin and Streptavidin
Biophysical journal 116(3), 151a - (2019) [10.1016/j.bpj.2018.11.840]2019 BibTeX | EndNote: XML, Text | RIS

Journal Article Schemmert, S.FZJ* ; Schartmann, E. ; Zafiu, C.FZJ* ; Kass, B.FZJ* ; Hartwig, S. ; Lehr, S. ; Bannach, O.FZJ* ; Langen, K.-J.FZJ* ; Shah, N. J.FZJ* ; Kutzsche, J.FZJ* ; Willuweit, A. (Corresponding author)FZJ* ; Willbold, D. (Corresponding author)FZJ*
Aβ Oligomer Elimination Restores Cognition in Transgenic Alzheimer’s Mice with Full-blown Pathology
Molecular neurobiology 56(3), 2211-2223 (2019) [10.1007/s12035-018-1209-3]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Schemmert, S.FZJ* ; Schartmann, E. ; Honold, D.FZJ* ; Zafiu, C.FZJ* ; Ziehm, T.FZJ* ; Langen, K.-J.FZJ* ; Shah, N. J.FZJ* ; Kutzsche, J.FZJ* ; Willuweit, A. (Corresponding author)FZJ* ; Willbold, D. (Corresponding author)FZJ*
Deceleration of the neurodegenerative phenotype in pyroglutamate-Aβ accumulating transgenic mice by oral treatment with the Aβ oligomer eliminating compound RD2
Neurobiology of disease 124, 36-45 (2019) [10.1016/j.nbd.2018.10.021]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Schmidt, D. ; Boehm, M. ; McClendon, C. L. ; Torella, R. ; Gohlke, H. (Corresponding author)FZJ*
Cosolvent-enhanced Sampling and Unbiased Identification of Cryptic Pockets Suitable for Structure-based Drug Design
Journal of chemical theory and computation 15(5), 3331–3343 (2019) [10.1021/acs.jctc.8b01295]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Schott-Verdugo, S. ; Gohlke, H. (Corresponding author)FZJ*
PACKMOL-Memgen: A Simple-To-Use, Generalized Workflow for Membrane-Protein–Lipid-Bilayer System Building
Journal of chemical information and modeling 59(6), 2522-2528 (2019) [10.1021/acs.jcim.9b00269]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Schott-Verdugo, S. ; Müller, L. ; Classen, E. ; Gohlke, H. (Corresponding author)FZJ* ; Groth, G. (Corresponding author)
Structural Model of the ETR1 Ethylene Receptor Transmembrane Sensor Domain
Scientific reports 9(1), 8869 (2019) [10.1038/s41598-019-45189-w]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Contribution to a book Schwarten, M.FZJ* ; Weiergräber, O. H.FZJ* ; Petrović, D.FZJ* ; Strodel, B.FZJ* ; Willbold, D. (Corresponding author)FZJ*
Structural Studies of Autophagy-Related Proteins
2019Autophagy / Ktistakis, Nicholas (Editor) Chapter 2 ; ISSN: 1064-3745=1940-6029 ; ISBN: 978-1-4939-8872-3=978-1-4939-8873-0 ; doi:10.1007/978-1-4939-8873-0 New York, NY : Springer New York, Methods in Molecular Biology 1880, 17 - 56 (2019) [10.1007/978-1-4939-8873-0_2]2019 Files BibTeX | EndNote: XML, Text | RIS

Journal Article Sengupta, U. ; Carballo-Pacheco, M. ; Strodel, B. (Corresponding author)FZJ*
Automated Markov state models for molecular dynamics simulations of aggregation and self-assembly
The journal of chemical physics 150(11), 115101 - (2019) [10.1063/1.5083915]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Simons, I. M. ; Mohrlüder, J.FZJ* ; Feederle, R. ; Kremmer, E. ; Zobel, T. ; Dobner, J.FZJ* ; Bleffert, N.FZJ* ; Hoffmann, S. (Corresponding author)FZJ* ; Willbold, D. (Corresponding author)FZJ*
The highly GABARAP specific rat monoclonal antibody 8H5 visualizes GABARAP in immunofluorescence imaging at endogenous levels
Scientific reports 9(1), 526 (2019) [10.1038/s41598-018-36717-1]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Simons, I. M.FZJ* ; Mohrlüder, J.FZJ* ; Feederle, R. ; Kremmer, E. ; Zobel, T. ; Dobner, J.FZJ* ; Bleffert, N.FZJ* ; Hoffmann, S.FZJ* ; Willbold, D. (Corresponding author)FZJ*
Author Correction: The highly GABARAP specific rat monoclonal antibody 8H5 visualizes GABARAP in immunofluorescence imaging at endogenous levels
Scientific reports 9(1), 19221 (2019) [10.1038/s41598-019-55814-3]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Stabinska, J. (Corresponding author) ; Neudecker, P.FZJ* ; Ljimani, A. ; Wittsack, H. ; Lanzman, R. S. ; Müller‐Lutz, A.
Proton exchange in aqueous urea solutions measured by water‐exchange (WEX) NMR spectroscopy and chemical exchange saturation transfer (CEST) imaging in vitro
Magnetic resonance in medicine 82(3), 935-947 (2019) [10.1002/mrm.27778]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Strodel, B.FZJ* ; Coskuner-Weber, O. (Corresponding author)
Transition Metal Ion Interactions with Disordered Amyloid-β Peptides in the Pathogenesis of Alzheimer’s Disease: Insights from Computational Chemistry Studies
Journal of chemical information and modeling 59(5), 1782 - 1805 (2019) [10.1021/acs.jcim.8b00983]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Tanabe, K. ; Bonus, M. ; Tomiyama, S. ; Miyoshi, K. ; Nagi, M. ; Niimi, K. ; Chindamporn, A. ; Gohlke, H.FZJ* ; Schmitt, L. ; Cannon, R. D. ; Niimi, M. (Corresponding author) ; Lamping, E. (Corresponding author)
FK506 resistance of Saccharomyces cerevisiae Pdr5 and Candida albicans Cdr1 involves mutations in the transmembrane domains and extracellular loops
Antimicrobial agents and chemotherapy 63(1), e01146-18 (2019) [10.1128/AAC.01146-18]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Van Den Berge, N. (Corresponding author) ; Ferreira, N. ; Gram, H. ; Mikkelsen, T. W. ; Alstrup, A. K. O. ; Casadei, N. ; Tsung-Pin, P. ; Riess, O. ; Nyengaard, J. R. ; Tamgüney, G.FZJ* ; Jensen, P. H. ; Borghammer, P.
Evidence for bidirectional and trans-synaptic parasympathetic and sympathetic propagation of alpha-synuclein in rats
Acta neuropathologica 138(4), 535 - 550 (2019) [10.1007/s00401-019-02040-w]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Viennet, T. ; Bungert-Plümke, S. ; Elter, S. ; Viegas, A. ; Fahlke, C. (Corresponding author)FZJ* ; Etzkorn, M. (Corresponding author)FZJ*
Reconstitution and NMR Characterization of the Ion-Channel Accessory Subunit Barttin in Detergents and Lipid-Bilayer Nanodiscs
Frontiers in molecular biosciences 6, 13 (2019) [10.3389/fmolb.2019.00013]2019 Files Fulltext by OpenAccess repository Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Vlasov, A. V. ; Kovalev, K. V. ; Marx, S.-H. ; Round, E. S. ; Gushchin, I. Y. ; Polovinkin, V. A. ; Tsoy, N. M. ; Okhrimenko, I. S. ; Borshchevskiy, V. I.FZJ* ; Büldt, G. D. ; Ryzhykau, Y. L. ; Rogachev, A. V. ; Chupin, V. V. ; Kuklin, A. I. ; Dencher, N. A. ; Gordeliy, V. I. (Corresponding author)FZJ*
Unusual features of the c-ring of F1FO ATP synthases
Scientific reports 9(1), 18547 (2019) [10.1038/s41598-019-55092-z]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Wang, C. ; Engelke, L. ; Bickel, D. ; Hamacher, A. ; Frank, M. ; Proksch, P. ; Gohlke, H.FZJ* ; Kassack, M. U. (Corresponding author)
The tetrahydroxanthone-dimer phomoxanthone A is a strong inducer of apoptosis in cisplatin-resistant solid cancer cells
Bioorganic & medicinal chemistry 27(19), 115044 (2019) [10.1016/j.bmc.2019.115044]2019 BibTeX | EndNote: XML, Text | RIS

Journal Article Weber, J. ; Petrović, D. ; Strodel, B.FZJ* ; Smits, S. H. J. ; Kolkenbrock, S. ; Leggewie, C. ; Jaeger, K.-E. (Corresponding author)FZJ*
Interaction of carbohydrate-binding modules with poly(ethylene terephthalate)
Applied microbiology and biotechnology 103(12), 4801 - 4812 (2019) [10.1007/s00253-019-09760-9]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Wienen-Schmidt, B. ; Schmidt, D. ; Gerber, H.-D. ; Heine, A. ; Gohlke, H.FZJ* ; Klebe, G. (Corresponding author)
Surprising Non-Additivity of Methyl-Groups in Drug-Kinase Interaction
ACS chemical biology 14(12), 2585-2594 (2019) [10.1021/acschembio.9b00476]2019 Files BibTeX | EndNote: XML, Text | RIS

Journal Article Wifling, D. ; Pfleger, C. ; Kaindl, J. ; Ibrahim, P. ; Kling, R. ; Buschauer, A. ; Gohlke, H. (Corresponding author)FZJ* ; Clark, T. (Corresponding author)
Basal Histamine H4 Receptor Activation: Agonist Mimicry by the Diphenylalanine Motif
Chemistry - a European journal 25(64), 14613-14624 (2019) [10.1002/chem.201902801]2019 Files BibTeX | EndNote: XML, Text | RIS

Journal Article Willbold, D. (Corresponding author)FZJ* ; Kutzsche, J.FZJ*
Do We Need Anti-Prion Compounds to Treat Alzheimer’s Disease?
Molecules 24(12), 2237 - (2019) [10.3390/molecules24122237]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Zhang, T.FZJ* ; Loschwitz, J.FZJ* ; Strodel, B.FZJ* ; Nagel-Steger, L.FZJ* ; Willbold, D. (Corresponding author)FZJ*
Interference with Amyloid-β Nucleation by Transient Ligand Interaction
Molecules 24(11), 2129 - (2019) [10.3390/molecules24112129]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Zhang, T.FZJ* ; Nagel-Steger, L. (Corresponding author)FZJ* ; Willbold, D.FZJ*
Solution-Based Determination of Dissociation Constants for the Binding of Aβ42 to Antibodies
ChemistryOpen 8(7), 989 - 994 (2019) [10.1002/open.201900167]2019 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Zhang, T. ; Gering, I.FZJ* ; Kutzsche, J.FZJ* ; Nagel-Steger, L.FZJ* ; Willbold, D. (Corresponding author)FZJ*
Toward the Mode of Action of the Clinical Stage All- d -Enantiomeric Peptide RD2 on Aβ42 Aggregation
ACS chemical neuroscience 10(12), 4800 - 4809 (2019) [10.1021/acschemneuro.9b00458]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Journal Article Zhang, Y.FZJ* ; Figueroa-Miranda, G. ; Zafiu, C.FZJ* ; Willbold, D.FZJ* ; Offenhäusser, A.FZJ* ; Mayer, D. (Corresponding author)FZJ*
Amperometric Aptasensor for Amyloid-β Oligomer Detection by Optimized Stem-Loop Structures with an Adjustable Detection Range
ACS sensors 4(11), 3042 - 3050 (2019) [10.1021/acssensors.9b01630]2019 Embargoed OpenAccess Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Letzte Änderung: 23.05.2022