Publikationen 2017
Journal Article
The Atg8 Family of Proteins—Modulating Shape and Functionality of Autophagic Membranes
Frontiers in genetics 8, 109 (2017) [10.3389/fgene.2017.00109]
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Journal Article
Using Neutron Reflectometry to Characterize Antimicrobial Protein Surface Coatings
The journal of physical chemistry <Washington, DC> / B 121(24), 5908–5916 (2017) [10.1021/acs.jpcb.7b02886]
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Journal Article
Structure of a LOV protein in apo-state and implications for construction of LOV-based optical tools
Scientific reports 7, 42971 - (2017) [10.1038/srep42971]
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Contribution to a book
The Structure of the Polar Core Mutant R175E and Its Functional Implications
The Structural Basis of Arrestin Functions
Cham : Springer International Publishing 143-158 (2017) [10.1007/978-3-319-57553-7_11]
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Journal Article
Heterologous expression of the Halothiobacillus neapolitanus carboxysomal gene cluster in Corynebacterium glutamicum
Journal of biotechnology 258, 126-135 (2017) [10.1016/j.jbiotec.2017.03.019]
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Journal Article
Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization
Scientific reports 7, 5979 (2017) [10.1038/s41598-017-06319-4]
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Journal Article
Comparison of force fields for Alzheimer's A β42: A case study for intrinsically disordered proteins
Protein science 26(2), 174 - 185 (2017) [10.1002/pro.3064]
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Journal Article
On the potential alternate binding change mechanism in a dimeric structure of Pyruvate Phosphate Dikinase
Scientific reports 7(1), 8020 (2017) [10.1038/s41598-017-08521-w]
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Journal Article
Pyroglutamate-modified Aβ(3-42) affects aggregation kinetics of Aβ(1-42) by accelerating primary and secondary pathways
Chemical science 8(7), 4996 - 5004 (2017) [10.1039/C6SC04797A]
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Journal Article
Pyroglutamate-Modified Amyloid- β (3–42) Shows α -Helical Intermediates before Amyloid Formation
Biophysical journal 112(8), 1621 - 1633 (2017) [10.1016/j.bpj.2017.03.007]
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Journal Article
Surprisingly high stability of the Aβ oligomer eliminating all-d-enantiomeric peptide D3 in media simulating the route of orally administered drugs
European journal of pharmaceutical sciences 107, 203-207 (2017) [10.1016/j.ejps.2017.07.015]
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Journal Article
Structure and phase transitions of DMPC multilamellar vesicles in the presence of Ca2+ ions
Journal of surface investigation 11(1), 27–37 (2017) [10.1134/S1027451016050499]
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Journal Article
Fibril structure of amyloid-ß(1-42) by cryoelectron microscopy
Science 358, 116-119 (2017) [10.1126/science.aao2825]
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Journal Article
Mechanism of transmembrane signaling by sensor histidine kinases
Science 356(6342), 6345 (2017) [10.1126/science.aah6345]
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Journal Article
Tertiary Interactions in the Unbound Guanine-Sensing Riboswitch Focus Functional Conformational Variability on the Binding Site
Journal of chemical information and modeling 57(11), 2822–2832 (2017) [10.1021/acs.jcim.7b00567]
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Journal Article
Rigidity theory for biomolecules: concepts, software, and applications
Wiley interdisciplinary reviews / Computational Molecular Science 7(4), e1311 (2017) [10.1002/wcms.1311]
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Journal Article
sFIDA automation yields sub-femtomolar limit of detection for Aβ aggregates in body fluids
Clinical biochemistry 50(4-5), 244-247 (2017) [10.1016/j.clinbiochem.2016.11.001]
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Journal Article
Nanoparticle standards for immuno-based quantitation of α-synuclein oligomers in diagnostics of Parkinson's disease and other synucleopathies
Clinica chimica acta 466, 152–159 (2017) [10.1016/j.cca.2017.01.010]
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Journal Article
New Insights on Signal Propagation by Sensory Rhodopsin II/Transducer Complex
Scientific reports 7, 41811 (2017) [10.1038/srep41811]
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Journal Article
A combination of mutational and computational scanning guides the design of an artificial ligand-binding controlled lipase
Scientific reports 7, 42592 - (2017) [10.1038/srep42592]
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Journal Article
Abstract 2496: Targeting brain tumor stem cells by interfering with choline metabolism: Evidence for an EMT-choline oncometabolic network
Cancer research 77(13), 2496 (2017) [10.1158/1538-7445.AM2017-2496]
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Journal Article
Analysis of anticoagulants for blood-based quantitation of amyloid β oligomers in the sFIDA assay
Biological chemistry 398(4), 465–475 (2017) [10.1515/hsz-2016-0153]
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Journal Article
EDTA aggregates induce SYPRO orange-based fluorescence in thermal shift assay
PLoS one 12, e0177024 (2017) [10.1371/journal.pone.0177024]
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Journal Article
Enzyme Architecture: Modeling the Operation of a Hydrophobic Clamp in Catalysis by Triosephosphate Isomerase
Journal of the American Chemical Society 139(30), 10514–10525 (2017) [10.1021/jacs.7b05576]
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Journal Article
Lactones from the Sponge-Derived Fungus Talaromyces rugulosus
Marine drugs 15, 359 (2017) [10.3390/md15110359]
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Journal Article
Large-Scale Oral Treatment Study with the Four Most Promising D3-Derivatives for the Treatment of Alzheimer’s Disease
Molecules 22, 1693 (2017) [10.3390/molecules22101693]
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Journal Article
Conformational Transitions of the Amyloid-β Peptide Upon Copper(II) Binding and pH Changes
Israel journal of chemistry 57(7-8), 771–784 (2017) [10.1002/ijch.201600108]
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Journal Article
Fast iodide-SAD phasing for high-throughput membrane protein structure determination
Science advances 3(5), e1602952 (2017) [10.1126/sciadv.1602952]
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Journal Article
New 2-Methoxy Acetylenic Acids and Pyrazole Alkaloids from the Marine Sponge Cinachyrella sp.
Marine drugs 15, 356 (2017) [10.3390/md15110356]
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Journal Article
Cyclic Cystine-Bridged Peptides from the Marine Sponge Clathria basilana Induce Apoptosis in Tumor Cells and Depolarize the Bacterial Cytoplasmic Membrane
Journal of natural products 80(11), 2941–2952 (2017) [10.1021/acs.jnatprod.7b00477]
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Journal Article
Antibacterial and Cytotoxic Phenolic Metabolites from the Fruits of Amorpha fruticosa
Journal of natural products 80(1), 169–180 (2017) [10.1021/acs.jnatprod.6b00809]
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Journal Article
Integral Membrane Proteins Can Be Crystallized Directly from Nanodiscs
Journal of crystal growth 17(3), 945–948 (2017) [10.1021/acs.cgd.6b01631]
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Journal Article
Protein Stability and Unfolding Following Glycine Radical Formation
Molecules 22(4), 655 (2017) [10.3390/molecules22040655] special issue: "Biomolecular Simulations"
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Journal Article
Multiple WW domains of Nedd4-1 undergo conformational exchange that is quenched upon peptide binding
FEBS letters 591(11), 1573 - 1583 (2017) [10.1002/1873-3468.12664]
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Journal Article
Shuffling Active Site Sub-State Populations Impacts Catalytic Activity: The Case of Glucose Oxidase
ACS catalysis 7, 6188–6197 (2017) [10.1021/acscatal.7b01575]
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Journal Article
Ca2+-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopy
Proceedings of the National Academy of Sciences of the United States of America 114, 6782-6787 (2017) [10.1073/pnas.1700868114]
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Journal Article
Molecular Dynamics Simulations Reveal Key Roles of the Interleukin-6 Alpha Receptor in the Assembly of the Human Interleukin-6 Receptor Complex
The journal of physical chemistry letters 121, 8113-8122 (2017) [10.1021/acs.jpcb.7b05732]
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Contribution to a book
Expression and purification of arrestin in yeast Saccharomyces cerevisiae
Methods in Cell Biology - G Protein-Coupled Receptors
San Diego, US : Academic Press 159-172 (2017)
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Journal Article
Fluorescence correlation spectroscopy reveals a cooperative unfolding of monomeric amyloid-β 42 with a low Gibbs free energy
Scientific reports 7, 2154 (2017) [10.1038/s41598-017-02410-y]
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Journal Article
$^{1}$H, $^{13}$C, and $^{15}$N backbone and sidechain resonance assignments of a monomeric variant of E. coli deoxyribose-5-phosphate aldolase
Biomolecular NMR assignments 11(2), 197-201 (2017) [10.1007/s12104-017-9747-6]
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Contribution to a book
6 - Sodium and Engineered Potassium Light-Driven Pumps
Optogenetics from Neuronal Function to Mapping and Disease Biology
Massachusetts : Cambridge University Press 77-78 (2017)
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Journal Article
Contribution of single amino acid and codon substitutions to the production and secretion of a lipase by Bacillus subtilis
Microbial cell factories 16(1), 160 (2017) [10.1186/s12934-017-0772-z]
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Communication
Learning from simulations
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Journal Article
Structural basis for the regulatory interactions of proapoptotic Par-4
Cell death and differentiation 24, 1540–1547 (2017) [10.1038/cdd.2017.76]
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Journal Article
Conformational Heterogeneity in a Fully Complementary DNA Three-Way Junction with a GC-Rich Branchpoint.
Biochemistry 56(37), 4985–4991 (2017) [10.1021/acs.biochem.7b00677]
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Journal Article
New amide and dioxopiperazine derivatives from leaves of Breynia nivosa
Fitoterapia 122, 16-19 (2017) [10.1016/j.fitote.2017.08.009]
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Journal Article
The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pathology
Scientific reports 7(1), 16275 (2017) [10.1038/s41598-017-16565-1]
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Journal Article
Enhancing the Catalytic Deamination Activity of APOBEC3C Is Insufficient to Inhibit Vif-Deficient HIV-1
Journal of molecular biology 429(8), 1171–1191 (2017) [10.1016/j.jmb.2017.03.015]
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Journal Article
Photo-voltage of highly-oriented bacteriorhodopsin in purple membranes: Possibilities for bio solar cells
Optoelectronics and advanced materials - rapid communications 11(1-2), 65-67 (2017)
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Journal Article
Structural insights into ion conduction by channelrhodopsin 2
Science 358(6366), eaan8862 (2017) [10.1126/science.aan8862]
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Journal Article
Secondary Metabolites of the Lichen-Associated Fungus Apiospora montagnei
Tetrahedron letters 58(17), 1702–1705 (2017) [10.1016/j.tetlet.2017.03.052]
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Contribution to a book
Investigating Structure and Dynamics of Atg8 Family Proteins
New York, NY [u.a.] : Elsevier, Methods in enzymology 587, 115–142 (2017) [10.1016/bs.mie.2016.09.056]
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Dissertation / PhD Thesis
Structural characterization of recombinant fibrillar human Islet Amyloid Polypeptide by solid-state Nuclear Magnetic Resonance Spectroscopy
114 p (2017) = Dissertation, HHU Düsseldorf, 2017
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Journal Article
Aβ42 pentamers/hexamers are the smallest detectable oligomers in solution
Scientific reports 7, 2493 (2017) [10.1038/s41598-017-02370-3]
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Journal Article
Opposed effects of dityrosine formation in soluble and aggregated alpha-synuclein on fibril growth
Journal of molecular biology 429, 3018-3030 (2017) [10.1016/j.jmb.2017.09.005]
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Journal Article
Influence of solubilization and AD-mutations on stability and structure of human presenilins
Scientific reports 7(1), 17970 (2017) [10.1038/s41598-017-18313-x]
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Journal Article
A structural organization for the Disrupted in Schizophrenia 1 protein, identified by high-throughput screening, reveals distinctly folded regions, which are bisected by mental illness-related mutations
The journal of biological chemistry 292, 6468–6477 (2017) [10.1074/jbc.M116.773903]
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Journal Article
High-efficient production and biophysical characterisation of nicastrin, and ist interaction with APPC100
Scientific reports 7, 44297 (2017) [10.1038/srep44297]
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