Publikationen 2022

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The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors
Nature Communications 13(1), 4061 () [10.1038/s41467-022-31574-z] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Vasor: Accurate prediction of variant effects for amino acid substitutions in multidrug resistance protein 3
Hepatology communications 6(11), 3098-3111 () [10.1002/hep4.2088] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Total Synthesis of the Antimycobacterial Natural Product Chlorflavonin and Analogs via a Late-Stage Ruthenium(II)-Catalyzed ortho-C(sp2)-H-Hydroxylation
Pharmaceuticals 15(8), 984 - () [10.3390/ph15080984] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Development of a First-in-Class Small-Molecule Inhibitor of the C-Terminal Hsp90 Dimerization
ACS central science 8(5), 636–655 () [10.1021/acscentsci.2c00013] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Structural, mechanistic and physiological insights into phospholipase A-mediated membrane phospholipid degradation in Pseudomonas aeruginosa
eLife 11, e72824 () [10.7554/eLife.72824] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Quantitative detection of α-Synuclein and Tau oligomers and other aggregates by digital single particle counting
npj Parkinson's Disease 8(1), 68 () [10.1038/s41531-022-00330-x] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Time-resolved structural analysis of an RNA-cleaving DNA catalyst
Nature <London> 601, 144-149 () [10.1038/s41586-021-04225-4] Embargoed OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Alpha-Synuclein-Specific Naturally Occurring Antibodies Inhibit Aggregation In Vitro and In Vivo
Biomolecules 12(3), 469 - () [10.3390/biom12030469] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Structure-Based Design of Stapled Peptides That Bind GABARAP and Inhibit Autophagy
Journal of the American Chemical Society 144(32), 14687 - 14697 () [10.1021/jacs.2c04699]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Single Stabilizing Point Mutation Enables High‐Resolution Co‐Crystal Structures of the Adenosine A 2A Receptor with Preladenant Conjugates
Angewandte Chemie / International edition 61(22), e202115545 () [10.1002/anie.202115545] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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CLC Anion/Proton Exchangers Regulate Secretory Vesicle Filling and Granule Exocytosis in Chromaffin Cells
The journal of neuroscience / Rapid communications 42(15), 3080 - 3095 () [10.1523/JNEUROSCI.2439-21.2022] Embargoed OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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The Secreted Metabolome of Hela Cells under Effect of Crotamine, a Cell-Penetrating Peptide from a Rattlesnake Using NMR-Based Metabolomics Analyses
BioMed 2(2), 238 - 254 () [10.3390/biomed2020020] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Spectroscopic and QM/MM studies of the Cu(I) binding site of the plant ethylene receptor ETR1
Biophysical journal 121(20), 3862-3873 () [10.1016/j.bpj.2022.09.007] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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A MademoiseLLE domain binding platform links the key RNA transporter to endosomes
PLoS Genetics 18(6), e1010269 - () [10.1371/journal.pgen.1010269] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Rational Design Yields Molecular Insights on Leaf-Binding of Anchor Peptides
ACS applied materials & interfaces 14(25), 28412–28426 () [10.1021/acsami.2c00648] Embargoed OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Discovery of all-D-peptide inhibitors of SARS CoV 2 3C-like protease
[10.26434/chemrxiv-2022-rjdzz] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Design of D-Amino Acids SARS-CoV-2 Main Protease Inhibitors Using the Cationic Peptide from Rattlesnake Venom as a Scaffold
Pharmaceuticals 15(5), 540 - () [10.3390/ph15050540] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Riboflavin, a Potent Neuroprotective Vitamin: Focus on Flavivirus and Alphavirus Proteases
Microorganisms 10(7), 1331 - () [10.3390/microorganisms10071331] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Critical Assessment of Structure-based Approaches to Improve Protein Resistance in Aqueous Ionic Liquids by Enzyme-wide Saturation Mutagenesis
Computational and structural biotechnology journal 20, 399-409 () [10.1016/j.csbj.2021.12.018] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein
Communications biology 5(1), 1040 () [10.1038/s42003-022-03948-y] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Atomic resolution insights into pH change induced deprotonation events in LS-shaped Aβ(1-42) amyloid fibrils
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Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects
Scientific reports 12(1), 14158 () [10.1038/s41598-022-17913-6] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Structure and function of redox-sensitive superfolder green fluorescent protein variant
Antioxidants & redox signaling 37(1-3), ars.2021.0234 () [10.1089/ars.2021.0234] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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A Computer-Aided Approach for the Discovery of D-Peptides as Inhibitors of SARS-CoV-2 Main Protease
Frontiers in molecular biosciences 8, 816166 () [10.3389/fmolb.2021.816166] special issue: "Interaction of Biomolecules and Bioactive Compounds with the SARS-CoV-2 Proteins: Molecular Simulations for the fight against Covid-19" OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Respiratory and C4-photosynthetic NAD-malic enzyme coexist in bundle sheath cell mitochondria and evolved via association of differentially adapted subunits
The plant cell 34(1), 597–615 () [10.1093/plcell/koab265]  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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The Crystal Structure of the Defense Conferring Rice Protein OsJAC1 Reveals a Carbohydrate Binding Site on the Dirigent-like Domain
Biomolecules 12(8), 1126 - () [10.3390/biom12081126] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Protein engineering for feedback resistance in 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase
Applied microbiology and biotechnology 106, 6505–6517 () [10.1007/s00253-022-12166-9] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Unsaturated fatty acids augment protein transport via the SecA:SecYEG translocon
The FEBS journal 289(1), 140-162 () [10.1111/febs.16140] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Aβ oligomer concentration in mouse and human brain and its drug-induced reduction ex vivo
Cell reports 3(5), 100630 - () [10.1016/j.xcrm.2022.100630] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Does the inclusion of electronic polarisability lead to a better modelling of peptide aggregation?
RSC Advances 12(32), 20829 - 20837 () [10.1039/D2RA01478E] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Structural Dissection of the First Events Following Membrane Binding of the Islet Amyloid Polypeptide
Frontiers in molecular biosciences 9, 849979 () [10.3389/fmolb.2022.849979] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Functional and structural characterization of interactions between opposite subunits in HCN pacemaker channels
Communications biology 5(1), 430 () [10.1038/s42003-022-03360-6] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Mapping the helix arrangement of the reconstituted ETR1 ethylene receptor transmembrane domain by EPR spectroscopy
RSC Advances 12, 7352 - 7356 () [10.1039/D2RA00604A] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Structural Analysis of Par-4 and Crystallographic Analysis of the Regulatory Domain
Tumor Suppressor Par-4 / Rangnekar, Vivek M. (Editor) ; Cham : Springer International Publishing, 2022, ; ISBN: 978-3-030-73571-5 ; doi:10.1007/978-3-030-73572-2 Cham : Springer International Publishing 127-150 () BibTeX | EndNote: XML, Text | RIS

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Ischemic stroke causes Parkinson’s disease-like pathology and symptoms in transgenic mice overexpressing alpha-synuclein
Acta Neuropathologica Communications 10(1), 26 () [10.1186/s40478-022-01327-6] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Cucurbit[7]uril Inhibits Islet Amyloid Polypeptide Aggregation by Targeting N Terminus Hot Segments and Attenuates Cytotoxicity.
Chemistry - a European journal 28(38), na/na () [10.1002/chem.202201698] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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CDC42-IQGAP Interactions Scrutinized: New Insights into the Binding Properties of the GAP-Related Domain.
International journal of molecular sciences 23(16), 8842 - () [10.3390/ijms23168842] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Multiscale MD simulations of wild‐type and sickle hemoglobin aggregation
Proteins 9(11), 1811-1824 () [10.1002/prot.26352] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Met/Val129 polymorphism of the full-length human prion protein dictates distinct pathways of amyloid formation
JBC papers in press 298(10), 102430 pp. () [10.1016/j.jbc.2022.102430] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Identification and Characterization of the Haloperoxidase VPO-RR from Rhodoplanes roseus by Genome Mining and Structure-Based Catalytic Site Mapping
Catalysts 12(10), 1195 - () [10.3390/catal12101195] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Physiological, Biochemical, and Structural Bioinformatic Analysis of the Multiple Inositol Dehydrogenases from Corynebacterium glutamicum
Microbiology spectrum 10(5), e01950-22 () [10.1128/spectrum.01950-22] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Recurrent Germline Variant in RAD21 Predisposes Children to Lymphoblastic Leukemia or Lymphoma
International journal of molecular sciences 23(9), 5174 - () [10.3390/ijms23095174] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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A So-Far Overlooked Secondary Conformation State in the Binding Mode of SARS-CoV-2 Spike Protein to Human ACE2 and Its Conversion Rate Are Crucial for Estimating Infectivity Efficacy of the Underlying Virus Variant
Journal of virology 96(13), e00685-22 () [10.1128/jvi.00685-22] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Solution NMR Spectroscopy as a Tool to Study DNAzyme Structure and Function
DNAzymes / Steger, Gerhard (Editor) ; New York, NY : Springer US, 2022, Chapter 10 ; ISSN: 1064-3745=1940-6029 ; ISBN: 978-1-0716-2046-5=978-1-0716-2047-2 ; doi:10.1007/978-1-0716-2047-2 New York, NY : Springer US, Methods in Molecular Biology 2439, 131 - 151 () [10.1007/978-1-0716-2047-2_10] BibTeX | EndNote: XML, Text | RIS

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Structural basis for the inhibition of IAPP fibril formation by the co-chaperonin prefoldin.
Nature Communications 13(1), 2363 () [10.1038/s41467-022-30042-y] OpenAccess  Download fulltext Files  Download fulltextFulltext by Pubmed Central Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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ATP synthase FOF1 structure, function, and structure-based drug design
Cellular and molecular life sciences 79(3), 179 () [10.1007/s00018-022-04153-0] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Structure and Dynamics of Human Chemokine CCL16—Implications for Biological Activity
Biomolecules 12(11), 1588 - () [10.3390/biom12111588] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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A phospholipase B from Pseudomonas aeruginosa with activity towards endogenous phospholipids affects biofilm assembly
Biochimica et biophysica acta / Molecular and cell biology of lipids 1867(4), 159101 - () [10.1016/j.bbalip.2021.159101] Embargoed OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Body-first Parkinson’s disease and variant Creutzfeldt–Jakob disease – similar or different?
Neurobiology of disease 164, 105625 () [10.1016/j.nbd.2022.105625] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Single MHC‐I Expression Promotes Virus‐Induced Liver Immunopathology
Hepatology communications 6(7), 1620-1633 () [10.1002/hep4.1913] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Uncoupling of Voltage- and Ligand-Induced Activation in HCN2 Channels by Glycine Inserts
Frontiers in physiology 13, 895324 () [10.3389/fphys.2022.895324] OpenAccess  Download fulltext Files  Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Letzte Änderung: 23.05.2022