TopDomain performs domain boundary prediction using multi-source information from over 50 primary predictors combined using deep neural networks. TopDomain takes either an input structure or an input sequence and predicts boundaries using sequence-based, homology-based and structure-based information.
A webserver is available here.
The stand-alone software can be accessed here.
Mulnaes et al. J. Chem. Theory Comput. (2021)