Proteins structures, dynamics and interactions with other biomolecules are intimately related to their functions in biological systems. We apply and develop computational techniques in the areas of bioinformatics, machine learning and computational biophysics to investigate the contribution of protein structures and dynamics to their function. The main research focus is the fundamental understanding and rational optimization of enzymes for bioeconomy, while specifically focusing on industrial and pharmaceutical utilisation. Computational predictions are routinely corroborated via the collaboration with experimental groups of various disciplines.
- Modeling of relevant membrane proteins for bioeconomy > read more
- Enzyme engineering for biocatalysis in ionic cosolvents > read more
- Machine learning for enzyme engineering/discovery > read more
- Computational next-generation biocatalysis > read more
- Computational pharmaceutical/medicinal chemistry > read more
Prof. Dr. Holger Gohlke
Building 05.11u / Room 2008