Research Projects in the Gohlke group

IBG-4 is involved in national and international third-party funded projects. Here you find an overview of projects currently funded and led in the group of Prof. Holger Gohlke:

National funding

Funded by the Helmholtz School for Data Science in Life, Earth and Energy (HDS-LEE)

TopEnzyme/TopEC: AI-based enzyme classification

Development of deep learning-based methods to improve classification of enzyme function.

Funded by Evoxx technologies GmbH

TAM: Knowledge-driven engineering of transaminase

Development and application of novel physics- and machine learning-based methods for the engineering of transaminases.

Funded by Bioeconomy Science Center

MetaProcess: Towards sustainable biocatalysis

Development of an enzymatic platform for the sustainable production of amino alcohols

Funded by BMBF

LipoBiocat: Engineering lipolytic biocatalysts

Improving lipolytic enzymes stability for indutrial applications

Funded by Volkswagen Stiftung

DNAzymes: Next-generation DNA editing biocatalysts

Development of innovative RNA-based biocatalysts

Funded by Bioeconomy Science Center

CasCAR: Improving carboxylic acid reductases catalytic performance

Sustainable production of valuable aldehydes using a locally immobilized synthetic enzyme cascade