Institute of Bio- and Geosciences (IBG)

Publications 2026

Publications of IBG-4 in 2026

Journal Article David, C.FZJ* ; Sun, Y. ; Woloschin, V. ; Vogt, M. ; Dienstbier, N. ; Friedrich, A. ; Krings, K. S. ; Schlütermann, D. ; Berning, L. ; Lungerich, B. ; Akgün, S. ; Mendiburo, M. J. ; Gertzen, C. G. W. ; Borkhardt, A. ; Wesselborg, S. ; Gohlke, H.FZJ* ; Bhatia, S. (Corresponding author) ; Kurz, T. (Corresponding author) ; Stork, B. (Corresponding author)
Small-molecule inhibitor of C‑terminal HSP90 dimerization modulates autophagy and functions synergistically with mTOR inhibition to kill cisplatin-resistant cancer cells
Cell death & disease 17, 130 (2026) [10.1038/s41419-025-08330-4]2026 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Demesa-Arevalo, E. ; Dӧrpholz, H.FZJ* ; Vardanega, I. ; Maika, J. E. ; Pineda-Valentino, I. ; Eggels, S.FZJ* ; Lautwein, T. ; Kӧhrer, K. ; Schnurbusch, T. ; von Korff, M. ; Usadel, B.FZJ* ; Simon, R. (Corresponding author)
Imputation integrates single-cell and spatial gene expression data to resolve transcriptional networks in barley shoot meristem development
Nature plants 12, 107–124 (2026) [10.1038/s41477-025-02176-6]2026 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Docter, S.FZJ* ; David, B.FZJ* ; Gohlke, H. (Corresponding author)FZJ*
Deep learning and generative artificial intelligence methods in enzyme and cell engineering
Current opinion in biotechnology 97, 103393 - (2026) [10.1016/j.copbio.2025.103393]2026 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Gorzkiewicz, M. ; Noseir, S. ; Vengurlekar, M. ; Ghosh, M. ; Katahira, I. ; Abromavičiūtė, D. ; Gerling-Driessen, U. ; Bonda, L. ; Rähse, N. ; Lapsien, M. ; Bockholt, S. ; Bergmann, J.FZJ* ; Kostadinovska, K. ; Fraii, H. ; Lang, K. S. ; Oestereich, L. ; Gohlke, H.FZJ* ; Hartmann, L. ; Lang, P. A. (Corresponding author)
Sulfated glycosaminoglycans inhibit LCMV entry and modulate antiviral immunity and pathology
EMBO molecular medicine 18, 1235-1264 (2026) [10.1038/s44321-026-00387-8]2026 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Heinrich, S. (Corresponding author) ; Behrendt, A. ; Sgodda, M. ; Gohlke, H.FZJ* ; Auber, B. ; Stalke, A. ; Hartleben, B. ; Wedemeyer, H. ; Cantz, T. ; Taubert, R.
Functional inactivation of MDR3 caused by a homozygous ABCB4 missense variant leading to liver failure
Frontiers in genetics 17, 1802238 (2026) [10.3389/fgene.2026.1802238]2026 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Holst, F. ; Bolger, A. M. ; Kindel, F.FZJ* ; Günther, C. ; Maß, J. ; Triesch, S. ; Kiel, N. ; Saadat, N. ; Ebenhöh, O. ; Usadel, B.FZJ* ; Schwacke, R.FZJ* ; Weber, A. P. M. ; Bolger, M. (Corresponding author)FZJ* ; Denton, A. K.
Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model
Nature methods 23, 732-739 (2026) [10.1038/s41592-025-02939-1]2026 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Kaiser, J. ; Gertzen, C. G. W. ; Mann, D.FZJ* ; Sachse, C.FZJ* ; Gohlke, H. (Corresponding author)FZJ*
Evidence for Epibatidine Binding to the Desensitization Gate in α7 nAChR from Molecular Dynamics Simulations and Cryo-EM
Journal of chemical information and modeling 66(3), 1337-1341 (2026) [10.1021/acs.jcim.5c02384]2026 Embargoed OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Kersten, L. S. ; Eberle, R. J. ; Groth, G. (Corresponding author) ; Gohlke, H. (Corresponding author)FZJ*
Integrative approaches for the structure‐based functional understanding of the ethylene response in plants
The plant journal 125(6), e70810 (2026) [10.1111/tpj.70810]2026 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article - Online First Lapsien, M. ; Bonus, M. ; Greb, J. ; Gohlke, H. (Corresponding author)FZJ*
LignAmb25: A comprehensive AMBER force field addressing lignin’s structural and chemical diversity
Biophysical journal NA, S0006349526002699 (2026) [10.1016/j.bpj.2026.04.004]2026 BibTeX | EndNote: XML, Text | RIS

Journal Article - Online First Martínez Rivas, F. J. (Corresponding author) ; Smith, M. A. ; Zangishei, Z. ; Alseekh, S. ; Usadel, B.FZJ* ; Plaxton, W. C. ; Fernie, A. R. (Corresponding author)
Malate matters: disrupting bacterial-type phosphoenolpyruvate carboxylase (BTPC) rewires tomato fruit development
Plant physiology NA, kiag026 (2026) [10.1093/plphys/kiag026]2026 BibTeX | EndNote: XML, Text | RIS

Journal Article Mezzetti, B. (Corresponding author) ; Usadel, B. (Corresponding author)FZJ* ; Osorio, S. (Corresponding author)
Editorial: Genomic and metabolomic diversity in fruit plants: impacts of breeding techniques
Frontiers in plant science 17, 1822028 (2026) [10.3389/fpls.2026.1822028]2026 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Modric, M.FZJ* ; Gentile, R. ; Moll, R. ; Alio, I. ; Streit, W. R. ; Jaeger, K.-E.FZJ* ; Gohlke, H. (Corresponding author)FZJ* ; Kovacic, F. (Corresponding author)
A Novel Approach to Combat Pseudomonas aeruginosa: Repurposing Pharmaceuticals for Inhibition of Phospholipase A
Microbiology spectrum 14(3), e01304-25 (2026) [10.1128/spectrum.01304-25]2026 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Nzivo, M. ; Gertzen, C. G. W. ; Luedde, T. ; Gohlke, H.FZJ* ; Münk, C. (Corresponding author)
Mechanisms of APOBEC3 Packaging into HIV-1
Viruses 18(3), 389 - (2026) [10.3390/v18030389]2026 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Op de Hipt, L.FZJ* ; Jäger, A.FZJ* ; Luthe, T.FZJ* ; Cevik, V. J. ; Kranz, A.FZJ* ; Wynands, B.FZJ* ; Frunzke, J.FZJ* ; Usadel, B.FZJ* ; Wierckx, N. (Corresponding author)FZJ*
Evolutionary engineering of Geobacillus thermoleovorans for growth on adipic acid and 1,4-butanediol
Applied microbiology and biotechnology 110(1), 139 (2026) [10.1007/s00253-026-13836-8]2026 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Pacheco-Ruiz, P. ; Senger, E.FZJ* ; Pott, D. M. ; Ziegler, F. M. R.FZJ* ; Jiménez, L. ; Sønsteby, A. ; Krüger, E. ; Chartier, P. ; Masny, A. ; Mott, D. ; Petit, A. ; Savini, G. ; Usadel, B.FZJ* ; Osorio, S. ; Vallarino, J. G. (Corresponding author)
Cultivar-by-environment interactions shape strawberry fruit quality: A multi-omics approach across European climates
Food chemistry 507, 148161 - (2026) [10.1016/j.foodchem.2026.148161]2026 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Papadopoulos, A. ; Anlauf, M. T. ; Reiners, J. ; Paik, S.-H.FZJ* ; Krüger, A.FZJ* ; Lückel, B. ; Bott, M.FZJ* ; Drepper, T.FZJ* ; Frunzke, J.FZJ* ; Gohlke, H.FZJ* ; Weidtkamp-Peters, S. ; Smits, S. H. J. (Corresponding author) ; Gertzen, C. G. W. (Corresponding author)
A Novel Biosensor for Ferrous Iron Developed via CoBiSe: A Computational Method for Rapid Biosensor Design
ACS sensors 11(1), 119-135 (2026) [10.1021/acssensors.5c02481]2026 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Rothkranz, B.FZJ* ; Klos, N.FZJ* ; Graf von Westarp, W. ; Hahn, D.FZJ* ; Classen, T.FZJ* ; Grabowski, L. ; Gentile, R. ; Kaiser, J. ; Schott-Verdugo, S.FZJ* ; Gohlke, H.FZJ* ; Jupke, A.FZJ* ; Rother, D. (Corresponding author)FZJ*
An Integrated Engineering Approach to Intensify the Biocatalytic Metaraminol Synthesis
ChemSusChem 19(4), e202502108 (2026) [10.1002/cssc.202502108]2026 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Schott-Verdugo, S.FZJ* ; Gohlke, H. (Corresponding author)FZJ*
Chat-Driven Computational (Bio)chemistry: Using LLM Agents to Accelerate Bio- and Chemoinformatics
Journal of chemical information and modeling 66(7), 3397 - 3401 (2026) [10.1021/acs.jcim.6c00633]2026 Embargoed OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Silvestre, S. ; Prigent, S. ; Pétriacq, P. ; Hassall, K. L. ; Le Boulch, M. ; Da Costa, A. ; Tellier, F. ; Alberghini, B. ; Aldorino, E. ; Hallab, A.FZJ* ; Großkinsky, D. K. ; Cassan, C. ; Monti, A. ; Prieto, J. ; Leon, P. ; Yambanis, Y. H. ; Gibon, Y. ; Usadel, B.FZJ* ; Faure, J.-D. ; Zanetti, F. ; Jonak, C. ; Haslam, R. P. (Corresponding author)
Assessment of phenotypic trait plasticity in the oilseed Camelina sativa using integrated early stage abiotic stress and field studies
Plant physiology 200(3), kiag052 (2026) [10.1093/plphys/kiag052]2026 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article Zhang, W. ; Jiang, X. ; Luo, S. ; Tariq, A. ; Buchmann, J. ; Gao, D. ; Zhang, X. ; Fernie, A. R. ; Usadel, B.FZJ* ; Wen, W. (Corresponding author)
The Camellia sinensis var. sinensis cv. Fuding Dabaicha genome unveils structural variation-driven metabolic innovation
Nature Communications 17, 1754 (2026) [10.1038/s41467-026-68463-8]2026 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Journal Article - Online First Zhao, M. ; Niimi, M. ; Niimi, K. ; Chindamporn, A. ; Kajiwara, S. ; Bonus, M. ; Gohlke, H.FZJ* ; Schmitt, L. ; Tyndall, J. D. A. ; Cannon, R. D. ; Lamping, E. (Corresponding author)
G521 is the gatekeeper and a key transmembrane domain contact residue of Candida albicans Cdr1
mBio NA, e03746-25 (2026) [10.1128/mbio.03746-25]2026 DBCoverage BibTeX | EndNote: XML, Text | RIS

Last Modified: 07.01.2026