Option for sterile fluid transfer

TO-150 • PT 1.2895 • As of 2/2024
Institute of Bio- and Geosciences
Biotechnology (IBG-1)

Technology

The device consists of two components. The first component is cone-shaped and accessible via a sterile barrier. The second component is a channel, e.g. in the form of a tube, with which the cone can be connected to the peripheral device.

Problem addressed

In biotechnology, the use of bioreactors requires great flexibility in terms of process control, sampling and analysis in order to be able to map the changing issues. The processes of adding and removing liquids, which in many cases must be sterile, are particularly relevant for reactors. The current approach is either a manual procedure or the use of very complex and less flexible system solutions. In order to ensure sterile handling, it is also necessary to work in a sterile environment such as a clean bench.

Solution

This device is a simple, inexpensive and sustainable alternative for sterile handling of sample liquids. Both the removal and addition of liquid can be mapped. It can also be used in an automated or robotized operation. In addition, no sterile room environment is required. The device is compatible with common conventional devices and therefore guarantees a high degree of flexibility.

Benefits and Potential Use

The device can be used in biotechnology for the sterile handling of liquids. This also includes automated or robotized systems.

Development Status and Next Steps

Prototypes are available and their functionality has already been tested.

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