RASER Technology: Unlocking Sub-Millihertz Precision in NMR Spectroscopy and Beyond

TO-198 • PT 1.2854 • As of 01/2025
Institute of Energy Technologies (IET)
Institute of Technology and Engineering (ITE-1)

Technology

This innovation addresses the limitations of nuclear magnetic resonance spectroscopy (NMR), which includes factors like signal quality, measurement time, and spectral resolution. To overcome these limitations, we introduce a novel technique which involves continuous oscillations of proton spins in organic molecules within the radiofrequency range. The key innovation is the use of a population inversion technique called Signal Amplification by Reversible Exchange (SABRE) coupled with a high-quality-factor resonator.

Problem addressed

Traditional NMR spectroscopy faces limitations in signal-to-noise ratio, measurement time, and linewidth due to T2 constraints. This technology overcomes these limitations by achieving continuous oscillations of proton spins in the radiofrequency range, creating a population inversion through signal amplification by reversible exchange (SABRE).

Solution

A novel liquid-state organic RASER offers sub-millihertz precision in measuring molecular structures, even at room temperature. It operates at higher temperatures, reducing the need for cryogenic conditions. The technology's multi-mode RASER activity provides unprecedented frequency resolution and sensitivity, surpassing previous methods.

Benefits and Potential Use

This breakthrough technology opens the door to high-precision measurements of magnetic fields, molecular coupling parameters, narrow-band amplifiers, and real-time NMR monitoring of metal-organic catalytic reactions. It also has promising applications in physics, chemistry, and material sciences, paving the way for a new era of precision spectroscopy.

Development Status and Next Steps

Forschungszentrum Jülich has extensive expertise in this field and holds several patents. The Central Institute of Engineering, Electronics and Analytics - Electronic Systems (ZEA-2) Is continuously seeking for cooperation partners and/or licensees in this and adjacent areas of research and applications.

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