Sex-Specific Differences in the Brain

9. Dezember 2024

Sex hormones also have an effect on our brain. This can lead to sex-specific differences in the microstructure of the brain, reports an international research team led by Dr. Sofie Valk from Forschungszentrum Jülich and the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig in the journal Nature Communications. The researcher and her colleagues also published a second study on sex differences in the same journal. In the article, they investigated the question of whether sex differences in the functional organization of the brain, i.e. in the processing of signals, depend on certain structural differences in the brain – for example, brain size. However, their results suggest that minor deviations in the functional networks and their connections play a role.

Read more in German

Wie beeinflussen Sexualhormone die Struktur des Gehirns?
AI / Dall-E

Original publications

Küchenhoff, S., Bayrak, Ş., Zsido, R.G. et al. Relating sex-bias in human cortical and hippocampal microstructure to sex hormones. Nat Commun 15, 7279 (2024). DOI: 10.1038/s41467-024-51459-7

Serio, B., Hettwer, M.D., Wiersch, L. et al. Sex differences in functional cortical organization reflect differences in network topology rather than cortical morphometry. Nat Commun 15, 7714 (2024). DOI: 10.1038/s41467-024-51942-1

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  • Institute of Neurosciences and Medicine (INM)
  • Brain and Behaviour (INM-7)
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Dr. Barbara Schunk

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    Last Modified: 16.12.2024