PET

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Positron emission tomography (PET) is a medical examination method. It makes metabolic processes in body, thus providing information about tumours or inflammations.



How it works

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Patients are injected with a weak radioactive substance, the tracer. This is usually glucose, which contains radioactive fluorine (1).

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In spots with a high metabolic activity, such as tumours and inflammations, a lot of sugar is consumed. That's where the tracer accumulates (2).

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The radioactive fluorine in the tracer decays. This produces photons that are measured by a detector. This can be used to calculate exactly where the tracer has accumulated and how much of it (3).

Fluoreszenz

Characteristic

This is what a PET scan of the brain looks like. Standard PET devices measure with an accuracy of about 4 millimetres. More precise results can be obtained by combining PET with computed tomography (CT), an X-ray technique. Metabolic activity correlates with colour intensity



What is Jülich doing with PET?

  • Understanding basic functions of the brain, such as the sleep process
  • Improving the detection of brain tumours
  • Studying diseases such as schizophrenia
  • Developing new tracers
  • Technically advancing the PET

This text is published in the effzett issue 1-19. Illustrations: Diana Köhne

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Last Modified: 14.03.2025